Search Results - "Babiaka, Smith"

StreptomeDB 3.0: an updated compendium of streptomycetes natural products by Moumbock, Aurélien F A, Gao, Mingjie, Qaseem, Ammar, Li, Jianyu, Kirchner, Pascal A, Ndingkokhar, Bakoh, Bekono, Boris D, Simoben, Conrad V, Babiaka, Smith B, Malange, Yvette I, Sauter, Florian, Zierep, Paul, Ntie-Kang, Fidele, Günther, Stefan

“…Abstract Antimicrobial resistance is an emerging global health threat necessitating the rapid development of novel antimicrobials. Remarkably, the vast…”
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AfroDb: a select highly potent and diverse natural product library from African medicinal plants by Ntie-Kang, Fidele, Zofou, Denis, Babiaka, Smith B, Meudom, Rolande, Scharfe, Michael, Lifongo, Lydia L, Mbah, James A, Mbaze, Luc Meva'a, Sippl, Wolfgang, Efange, Simon M N

“…Computer-aided drug design (CADD) often involves virtual screening (VS) of large compound datasets and the availability of such is vital for drug discovery…”
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StreptomeDB 4.0: a comprehensive database of streptomycetes natural products enriched with protein interactions and interactive spectral visualization by Feng, Yue, Qaseem, Ammar, Moumbock, Aurélien F A, Pan, Shuling, Kirchner, Pascal A, Simoben, Conrad V, Malange, Yvette I, Babiaka, Smith B, Gao, Mingjie, Günther, Stefan

“…Streptomycetes remain an important bacterial source of natural products (NPs) with significant therapeutic promise, particularly in the fight against…”
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Natural products in Cyperus rotundus L. (Cyperaceae): an update of the chemistry and pharmacological activities by Babiaka, Smith B., Moumbock, Aurélien F. A., Günther, Stefan, Ntie-Kang, Fidele

“…Cyperus rotundus L. (Nutgrass, family Cyperaceae) is a notorious weed which is widespread in temperate tropical and subtropical regions of the world. Owing to…”
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Challenges in natural product-based drug discovery assisted with in silico -based methods by Simoben, Conrad V, Babiaka, Smith B, Moumbock, Aurélien F A, Namba-Nzanguim, Cyril T, Eni, Donatus Bekindaka, Medina-Franco, José L, Günther, Stefan, Ntie-Kang, Fidele, Sippl, Wolfgang

“…The application of traditional medicine by humans for the treatment of ailments as well as improving the quality of life far outdates recorded history. To…”
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Natural Products as Potential Lead Compounds for Drug Discovery Against SARS-CoV-2 by Ebob, Oyere Tanyi, Babiaka, Smith B., Ntie-Kang, Fidele

“…For the past 2 years, the coronavirus responsible for the COVID-19 infection has become a world pandemic, ruining the lives and economies of several nations in…”
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Alkaloids with Anti-Onchocercal Activity from Voacanga africana Stapf (Apocynaceae): Identification and Molecular Modeling by Babiaka, Smith B, Simoben, Conrad V, Abuga, Kennedy O, Mbah, James A, Karpoormath, Rajshekhar, Ongarora, Dennis, Mugo, Hannington, Monya, Elvis, Cho-Ngwa, Fidelis, Sippl, Wolfgang, Loveridge, E Joel, Ntie-Kang, Fidele

“…A new iboga-vobasine-type isomeric bisindole alkaloid named voacamine A ( ), along with eight known compounds-voacangine ( ), voacristine ( ), coronaridine (…”
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Filaricidal activity of Daniellia oliveri and Psorospermum febrifugum extracts by Abongwa, Melanie, Samje, Moses, Ayimele, Godfred A, Babiaka, Smith B, Bulman, Christina, Sakanari, Judy, Koszewski, Nick J, Verma, Saurabh, Goff, Jesse, Cho-Ngwa, Fidelis, Martin, Richard J, Robertson, Alan P

“…Drugs currently used for controlling onchocerciasis and lymphatic filariasis (LF) are mainly microfilaricidal, with minimal or no effect on the adult worms…”
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Croton oligandrus Pierre & Hutch (Euphorbiaceae) Extracts and Isolated Compounds Reverse HIV-1 Latency by Emade Nkwelle, Chantal, Babiaka, Smith, Metuge, Clovis, Liang, Kimberly, Stephens, Unique, Esemu, Seraphine, Zuzga, David, Shuda McGuire, Kristy, Montaner, Luis, Ndip, Roland, Tietjen, Ian, Ntie-Kang, Fidele

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Leaf-Methanolic Extract of Pseudopanax arboreus (Araliaceae) (L. F. Phillipson) Reverses Amitriptyline-Induced Sexual Dysfunction in Male Rats by Kamanyi, Albert, Babiaka, Smith B., Ateufack, G., Besong, Egbe B.

“…The people of the Bayangi tribe (Manyu Division) of Cameroon have used the leaves of Pseudopanax arboreus (Araliaceae) traditionally for decades as an…”
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Bioassay-guided discovery of antibacterial agents: in vitro screening of Peperomia vulcanica, Peperomia fernandopoioana and Scleria striatinux by Mbah, James A, Ngemenya, Moses N, Abawah, Ashime Louis, Babiaka, Smith B, Nubed, Lina N, Nyongbela, Kennedy D, Lemuh, Njimoh Dieudonne, Efange, Simon M N

“…The global burden of bacterial infections is high and has been further aggravated by increasing resistance to antibiotics. In the search for novel…”
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In Vitro Antibacterial Potential against Multidrug-Resistant Salmonella, Cytotoxicity, and Acute Biochemical Effects in Mice of Annona muricata Leaf Extracts by Ngemenya, Moses Njutain, Asongana, Rodolph, Zofou, Denis, Ndip, Rita Ayuk, Itoe, Lamson Ottotoh, Babiaka, Smith Borakaeyabe

“…The treatment of Salmonella infections is threatened by multidrug resistance necessitating the search for alternative treatments, such as from medicinal…”
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Computational Applications in Secondary Metabolite Discovery (CAiSMD): an online workshop by Ntie-Kang, Fidele, Telukunta, Kiran K., Fobofou, Serge A. T., Chukwudi Osamor, Victor, Egieyeh, Samuel A., Valli, Marilia, Djoumbou-Feunang, Yannick, Sorokina, Maria, Stork, Conrad, Mathai, Neann, Zierep, Paul, Chávez-Hernández, Ana L., Duran-Frigola, Miquel, Babiaka, Smith B., Tematio Fouedjou, Romuald, Eni, Donatus B., Akame, Simeon, Arreyetta-Bawak, Augustine B., Ebob, Oyere T., Metuge, Jonathan A., Bekono, Boris D., Isa, Mustafa A., Onuku, Raphael, Shadrack, Daniel M., Musyoka, Thommas M., Patil, Vaishali M., van der Hooft, Justin J. J., da Silva Bolzani, Vanderlan, Medina-Franco, José L., Kirchmair, Johannes, Weber, Tilmann, Tastan Bishop, Özlem, Medema, Marnix H., Wessjohann, Ludger A., Ludwig-Müller, Jutta

“…We report the major conclusions of the online open-access workshop “Computational Applications in Secondary Metabolite Discovery (CAiSMD)” that took place from…”
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A Bioactivity Versus Ethnobotanical Survey of Medicinal Plants from Nigeria, West Africa by Lifongo, Lydia L., Simoben, Conrad V., Ntie-Kang, Fidele, Babiaka, Smith B., Judson, Philip N.

“…Traditional medicinal practices play a key role in health care systems in countries with developing economies. The aim of this survey was to validate the use…”
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In vitro activity against multi-drug resistant bacteria and cytotoxicity of lichens collected from Mount Cameroon by Bate, Petuel Ndip Ndip, Orock, Ayuk Elizabeth, Nyongbela, Kennedy Dohjinga, Babiaka, Smith Borakaeyabe, Kukwah, Anthony, Ngemenya, Moses N.

“…Natural products remain a promising source of new efficacious antimicrobials to counter increasing resistance and prevent emergence of multidrug and…”
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Molecular modeling of plant metabolites with anti-Onchocerca activity by Metuge, Jonathan Alunge, Ntie-Kang, Fidele, Ngwa, Valery Fuh, Babiaka, Smith B., Samje, Moses, Cho-Ngwa, Fidelis

“…Onchocerciasis or river blindness is a parasitic disease of man, caused by the filarial worm Onchocerca volvulus. It afflicts an estimated 37 million people,…”
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In vivo antibacterial activity of the methanol extract of Voacanga africana Stapf (Apocynaceae) stem bark against clinical multidrug-resistant Salmonella Typhimurium in Wistar rats by Awah, Laupy Anne, Taïwe, Germain Sotoing, Babiaka, Smith Borakaeyabe, Cho-Ngwa, Fidelis, Ngemenya, Moses Njutain

“…The emergence of multidrug-resistant (MDR) Salmonella has increased the burden of its infections. Voacanga africana, used traditionally to treat some bacterial…”
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Anti-onchocerca Metabolites from Cyperus articulatus: Isolation, In Vitro Activity and In Silico ‘Drug-Likeness’ by Metuge, Jonathan Alunge, Babiaka, Smith B., Mbah, James A., Ntie-Kang, Fidele, Ayimele, Godfred A., Cho-Ngwa, Fidelis

“…The aims of this investigation were to isolate active ingredients from the roots/rhizomes of Cyperus articulatus used as herbal medicine in Cameroon for the…”
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Antioxidant potential of flavonoid glycosides from Manniophyton fulvum Müll. (Euphorbiaceae): Identification and molecular modeling by Babiaka, Smith B., Nia, Rene, Abuga, Kennedy O., Mbah, James A., Nziko, Vincent de Paul N., Paper, Dietrich H., Ntie-Kang, Fidele

“…Chemical investigation of the leaves of Manniophyton fulvum led to the isolation of seven flavonoid glycosides: myricetin-3-O-β-Dd-rhamnoside (1),…”
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Filaricidal activities on Onchocerca ochengi and Loa loa, toxicity and phytochemical screening of extracts of Tragia benthami and Piper umbellatum by Cho-Ngwa, Fidelis, Monya, Elvis, Azantsa, Boris K, Manfo, Faustin Pascal T, Babiaka, Smith B, Mbah, James A, Samje, Moses

“…Onchocerciasis is the world's second leading infectious cause of blindness. Its control is currently hampered by the lack of a macrofilaricidal drug and by…”
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