Search Results - "Babcock, Gerald T"

How Oxygen Is Activated and Reduced in Respiration by Babcock, Gerald T.

“…In aerobic biochemistry, oxygen is used in a plethora of synthetic reactions that are fundamental to almost all aspects of cell growth, development, and…”
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A Metalloradical Mechanism for the Generation of Oxygen from Water in Photosynthesis by Hoganson, Curtis W., Babcock, Gerald T.

“…In plants and algae, photosystem II uses light energy to oxidize water to oxygen at a metalloradical site that comprises a tetranuclear manganese cluster and a…”
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Oxygen Activation and Reduction in Respiration: Involvement of Redox-Active Tyrosine 244 by Proshlyakov, Denis A., Pressler, Michelle A., DeMaso, Catherine, Leykam, Joseph F., DeWitt, David L., Babcock, Gerald T.

“…Cytochrome oxidase activates and reduces O2to water to sustain respiration and uses the energy released to drive proton translocation and adenosine…”
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Dioxygen activation and bond cleavage by mixed-valence cytochrome c oxidase by Proshlyakov, D.A. (Michigan State University, East Lansing, MI.), Pressler, M.A, Babcock, G.T

“…Elucidating the structures of intermediates in the reduction of O2 to water by cytochrome c oxidase is crucial to understanding both oxygen activation and…”
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Direct Electrochemistry of Cytochrome c at Nanocrystalline Boron-Doped Diamond by Haymond, Shannon, Babcock, Gerald T, Swain, Greg M

“…Direct electron transfer of horse heart cytochrome c is measured at a nanocrystalline boron-doped diamond thin-film electrode. A quasi-reversible,…”
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Inhibition of Soluble Guanylate Cyclase by ODQ by Zhao, Yunde, Brandish, Philip E, DiValentin, Marilena, Schelvis, Johannes P. M, Babcock, Gerald T, Marletta, Michael A

“…The heme in soluble guanylate cyclases (sGC) as isolated is ferrous, high-spin, and 5-coordinate. [1H-[1,2,4]oxadiazolo-[4,3-a]quinoxalin-1-one] (ODQ) has been…”
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Oxygen activation and the conservation of energy in cell respiration by Babcock, Gerald T, Wikström, Mårten

“…Many of the membrane-associated oxidases that catalyse respiratory reduction of O2 to water simultaneously couple this exergonic reaction to the translocation…”
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Identification of Histidine 105 in the β1 Subunit of Soluble Guanylate Cyclase as the Heme Proximal Ligand by Zhao, Yunde, Schelvis, Johannes P. M, Babcock, Gerald T, Marletta, Michael A

“…Soluble guanylate cyclase isolated from bovine and rat lung is a heterodimeric hemoprotein composed of α1 and β1 subunits. The heme binding region has been…”
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Cytochrome c and Cytochrome c Oxidase:  Monolayer Assemblies and Catalysis by Haas, Alan S, Pilloud, Denis L, Reddy, Konda S, Babcock, Gerald T, Moser, Christopher C, Blasie, J. Kent, Dutton, P. Leslie

“…A novel electrochemical system has been designed and assembled to study the kinetic activity of cytochrome c oxidase. Gold electrodes coated with…”
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Modeling Cytochrome Oxidase:  A Quantum Chemical Study of the O−O Bond Cleavage Mechanism by Blomberg, Margareta R. A, Siegbahn, Per E. M, Babcock, Gerald T, Wikström, Mårten

“…The mechanism of O−O bond cleavage at the binuclear center in cytochrome oxidase has been investigated by using hybrid density functional theory (B3LYP). A…”
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Vibrational spectroscopy of the oxygen-evolving complex and of manganese model compounds by Chu, Hsiu-An, Hillier, Warwick, Law, Neil A, Babcock, Gerald T

“…A number of molecularly specific models for the oxygen-evolving complex in photosystem II (PSII) and of manganese–substrate water intermediates that may occur…”
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Spin-Density Distribution, Conformation, and Hydrogen Bonding of the Redox-Active Tyrosine YZ in Photosystem II from Multiple-Electron Magnetic-Resonance Spectroscopies: Implications for Photosynthetic Oxygen Evolution by Tommos, Cecilia, Tang, Xiao-Song, Warncke, Kurt, Hoganson, Curtis W, Styring, Stenbjoern, McCracken, John, Diner, Bruce A, Babcock, Gerald T

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High-Field EPR Study of Tyrosyl Radicals in Prostaglandin H2 Synthase-1 by Dorlet, Pierre, Seibold, Steve A, Babcock, Gerald T, Gerfen, Gary J, Smith, William L, Tsai, Ah-lim, Un, Sun

“…Various tyrosyl radicals generated by reaction of both native and indomethacin-inhibited ovine prostaglandin H synthase-1 with ethyl hydrogen peroxide were…”
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Role of the Conserved Arginine Pair in Proton and Electron Transfer in Cytochrome c Oxidase by Qian, Jie, Mills, Denise A, Geren, Lois, Wang, Keifei, Hoganson, Curt W, Schmidt, Bryan, Hiser, Carrie, Babcock, Gerald T, Durham, Bill, Millett, Francis, Ferguson-Miller, Shelagh

“…A hydrogen-bonded network is observed above the hemes in all of the high-resolution crystal structures of cytochrome oxidases. It includes water and a pair of…”
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Identification of a Mn−O−Mn Cluster Vibrational Mode of the Oxygen-Evolving Complex in Photosystem II by Low-Frequency FTIR Spectroscopy by Chu, Hsiu-An, Sackett, Heather, Babcock, Gerald T

“…We have developed conditions for recording the low-frequency S2/S1 Fourier transform infrared difference spectrum of hydrated PSII samples. By exchanging PSII…”
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D1-Asp170 Is Structurally Coupled to the Oxygen Evolving Complex in Photosystem II As Revealed by Light-Induced Fourier Transform Infrared Difference Spectroscopy by Chu, Hsiu-An, Debus, Richard J, Babcock, Gerald T

“…We report both mid-frequency (1800−1200 cm-1) and low-frequency (670−350 cm-1) S2/S1 FTIR difference spectra of photosystem II (PSII) particles isolated from…”
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A Quantum Chemical Study of Hydrogen Abstraction from Manganese-Coordinated Water by a Tyrosyl Radical:  A Model for Water Oxidation in Photosystem II by Blomberg, Margareta R. A, Siegbahn, Per E. M, Styring, Stenbjörn, Babcock, Gerald T, Åkermark, Björn, Korall, Peter

“…Recently, water oxidation in photosystem II was proposed to involve direct abstraction of hydrogen atoms from water molecules terminally ligated to manganese…”
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Origin of the Transient Electron Paramagnetic Resonance Signals in DNA Photolyase by Gindt, Yvonne M, Vollenbroek, Esther, Westphal, Kristi, Sackett, Heather, Sancar, Aziz, Babcock, Gerald T

“…DNA photolyase repairs pyrimidine dimer lesions in DNA through light-induced electron donation to the dimer. During isolation of the enzyme, the flavin…”
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Oxygen Production in Nature:  A Light-Driven Metalloradical Enzyme Process by Tommos, Cecilia, Babcock, Gerald T.

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Structural Changes in the Heme Proximal Pocket Induced by Nitric Oxide Binding to Soluble Guanylate Cyclase by Zhao, Yunde, Hoganson, Curtis, Babcock, Gerald T, Marletta, Michael A

“…When expressed in Escherichia coli, the heme domain [β1(1−385)] of rat lung soluble guanylate cyclase (sGC) is isolated with a stoichiometric amount of bound…”
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