Search Results - "Baatjes, Adrian"

IL-25 Receptor Expression on Airway Dendritic Cells after Allergen Challenge in Subjects with Asthma by Tworek, Damian, Smith, Steven G, Salter, Brittany M, Baatjes, Adrian J, Scime, Tara, Watson, Rick, Obminski, Caitlin, Gauvreau, Gail M, O'Byrne, Paul M

“…IL-25 is an epithelial-derived cytokine, whose effects are mediated by the IL-25 receptor (IL-17RB), and that has been implicated in the pathogenesis of…”
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Antisense Therapy against CCR3 and the Common Beta Chain Attenuates Allergen-induced Eosinophilic Responses by Gauvreau, Gail M, Boulet, Louis Philippe, Cockcroft, Donald W, Baatjes, Adrian, Cote, Johanne, Deschesnes, Francine, Davis, Beth, Strinich, Tara, Howie, Karen, Duong, MyLinh, Watson, Richard M, Renzi, Paolo M, O'Byrne, Paul M

“…The drug product TPI ASM8 contains two modified phosphorothioate antisense oligonucleotides designed to inhibit allergic inflammation by down-regulating human…”
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The effect of montelukast, budesonide alone, and in combination on exercise-induced bronchoconstriction by Duong, MyLinh, MBBS, Amin, Reshma, MD, Baatjes, Adrian J., MSc, Kritzinger, Fiona, MBChB, Qi, Ying, MSc, Meghji, Zahida, MSc, Lou, Wendy, PhD, Grasemann, Hartmut, PhD, O'Byrne, Paul M., MB, Subbarao, Padmaja, MD

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Natural regulatory T cells in isolated early responders compared with dual responders with allergic asthma by Kinoshita, Takashi, MD, Baatjes, Adrian, MSc, Smith, Steven G., PhD, Dua, Benny, MSc, Watson, Richard, BSc, Kawayama, Tomotaka, MD, Larche, Mark, PhD, Gauvreau, Gail M., PhD, O’Byrne, Paul M., MD, FRCPI

“…Background Natural regulatory T (Treg) cells are implicated in the regulation of the inflammatory response in patients with allergic asthma. Objectives We…”
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Toll‐like receptor‐mediated eosinophil–basophil differentiation: autocrine signalling by granulocyte–macrophage colony‐stimulating factor in cord blood haematopoietic progenitors by Reece, Pia, Baatjes, Adrian J., Cyr, Michael M., Sehmi, Roma, Denburg, Judah A.

“…Summary Eosinophils are multi‐functional leucocytes that play a role in inflammatory processes including allergy and infection. Although bone marrow (BM)…”
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Evaluation of peroxisome proliferator‐activated receptor agonists on interleukin‐5‐induced eosinophil differentiation by Smith, Steven G., Hill, Mike, Oliveria, John‐Paul, Watson, Brittany M., Baatjes, Adrian J., Dua, Benny, Howie, Karen, Campbell, Heather, Watson, Rick M., Sehmi, Roma, Gauvreau, Gail M.

“…Summary Peroxisome proliferator‐activated receptor (PPAR) agonists have been suggested as novel therapeutics for the treatment of inflammatory lung disease,…”
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Expression of functional cysteinyl leukotriene receptors by human basophils by Gauvreau, Gail M., Plitt, Jim R., Baatjes, Adrian, MacGlashan, Donald W.

“…Synthesis of leukotriene (LT) C 4 by basophils and mast cells is an important component of IgE-mediated inflammation, resulting in increased levels of the…”
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The effect of cysteinyl leukotrienes on growth of eosinophil progenitors from peripheral blood and bone marrow of atopic subjects by Braccioni, Fausto, Dorman, Sandra C., O'Byrne, Paul M., Inman, Mark D., Denburg, Judah A., Parameswaran, Krishnan, Baatjes, Adrian J., Foley, Ronan, Gauvreau, Gail M.

“…Background: The accumulation of eosinophils into the peripheral blood and airways of asthmatic subjects is, in part, dependent on cysteinyl leukotrienes…”
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Effects of a cysteinyl leukotriene receptor antagonist on eosinophil recruitment in experimental allergic rhinitis by Saito, Hiroko, Morikawa, Hiroshi, Howie, Karen, Crawford, Lynn, Baatjes, Adrian J., Denburg, Elisha, Cyr, Michael M., Denburg, Judah A.

“…Summary The cysteinyl leukotrienes (cysLTs) are potent lipid mediators in allergic disease, acting through a receptor (cysLT1‐R) which can be targeted in…”
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The effect of desloratadine on eosinophil/basophil progenitors and other inflammatory markers in seasonal allergic rhinitis: a placebo-controlled randomized study by Cyr, Michael M, Hayes, Lisa M, Crawford, Lynn, Baatjes, Adrian J, Keith, Paul K, Denburg, Judah A

“…Eosinophil/basophil (Eo/B) progenitors fluctuate in the peripheral circulation during seasonal allergen exposure in atopic subjects. Several drugs have been…”
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Anti-allergic therapies: effects on eosinophil progenitors by Baatjes, Adrian J, Sehmi, Roma, Saito, Hiroko, Cyr, Michael M, Dorman, Sandra C, Inman, Mark D, O'Byrne, Paul M, Denburg, Judah A

“…Marked eosinophilic infiltration is the typical inflammatory response associated with allergic inflammation. Previous research involving animal and human…”
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In vitro effects of budesonide on eosinophil-basophil lineage commitment by Cyr, Michael M, Baatjes, Adrian J, Dorman, Sandra C, Crawford, Lynn, Sehmi, Roma, Foley, Ronan, Alam, Rafeul, Byrne, Paul O', Denburg, Judah A

“…IL-5 is the primary cytokine that stimulates the production and survival of eosinophils and basophils from progenitor cells. The inhaled glucocorticoid,…”
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Biologic therapy in rare eosinophil-associated disorders: remaining questions and translational research opportunities by Khoury, Paneez, Roufosse, Florence, Kuang, Fei Li, Ackerman, Steven J, Akuthota, Praveen, Bochner, Bruce S, Johansson, Mats W, Mathur, Sameer K, Ogbogu, Princess U, Spencer, Lisa A, Wechsler, Michael E, Zimmermann, Nives, Klion, Amy D

“…Rare eosinophil-associated disorders (EADs), including hypereosinophilic syndrome, eosinophilic granulomatosis with polyangiitis, and eosinophilic…”
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Allergen-induced Changes in Bone Marrow and Airway Dendritic Cells in Subjects with Asthma by El-Gammal, Amani, Oliveria, John-Paul, Howie, Karen, Watson, Richard, Mitchell, Patrick, Chen, Ruchong, Baatjes, Adrian, Smith, Steven, Al-Sajee, Dhuha, Hawke, Thomas J, Killian, Kieran J, Gauvreau, Gail M, O'Byrne, Paul M

“…Dendritic cells (DCs) are antigen-presenting cells essential for the initiation of T-cell responses. Allergen inhalation increases the number of airway DCs and…”
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Type 2 innate lymphoid cells expressing death receptor 3 are increased in airway of mild atopic asthmatic subject following allergen inhalation challenge by Machida, Kentaro, Baatjes, Adrian, Watson, Richard, Scime, Tara, Gauvreau, Gail M., O'Byrne, Paul M., Sehmi, Roma

“…To understand novel mechanisms of ILC2 activation, we investigated the role of death receptor 3 (DR3) and its cognate ligand, tumor necrosis factor like…”
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Allergen‐induced fluctuation in CC chemokine receptor 3 expression on bone marrow CD34+ cells from asthmatic subjects: significance for mobilization of haemopoietic progenitor cells in allergic inflammation by Sehmi, Roma, Dorman, Sandra, Baatjes, Adrian, Watson, Rick, Foley, Ronan, Ying, Sun, Robinson, Douglas S., Kay, A. Barry, O'Byrne, Paul M., Denburg, Judah A.

“…Summary There is increasing evidence that primitive progenitors migrate from the bone marrow (BM) via the peripheral circulation to tissue sites where they…”
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effects of montelukast on tissue inflammatory and bone marrow responses in murine experimental allergic rhinitis: interaction with interleukin-5 deficiency by Roa, Johanna, Morikawa, Hiroshi, Crawford, Lynn, Baatjes, Adrian, Duong, Mylinh, Denburg, Judah A

“…The cysteinyl leukotrienes (cysLTs) are potent lipid mediators in allergic disease, acting through the receptors, cysLT1R and cysLTR2, and are produced by…”
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Proceedings of the Canadian society of allergy and clinical immunology annual scientific meeting 2015 by Côté, Marie-Ève, Boulay, Marie-Ève, Plante, Sophie, Chakir, Jamila, Boulet, Louis-Philippe, Ahmed, Hanan, Ospina, Maria-Beatriz, Sideri, Kyriaki, Vliagoftis, Harissios, Johnson, Sara F., Woodgate, Roberta L., Cros, Guilhem, Teira, Pierre, Cellot, Sonia, Bittencourt, Henrique, Decaluwe, Helene, Vachon, Marie France, Duval, Michel, Haddad, Elie, Kim, Vy H. D., Pham-Huy, Anne, Grunebaum, Eyal, Oliveria, John-Paul, Phan, Stephanie, Tenn, Mark W., Tworek, Damian, Smith, Steven G., Baatjes, Adrian J., Obminski, Caitlin D., Munoz, Caroline E., Scime, Tara X., Sehmi, Roma, Gauvreau, Gail M., Salter, Brittany M., Schlatman, Abbey, Watson, Rick, Sherkat, Roya, Khoshnevisan, Razieh, Sheikhbahaei, Saba, Betschel, Stephen, Warrington, Richard, Schellenberg, Robert, Fein, Michael N., Pelletier, Jean-Philippe, Kan, Manstein, Labrosse, Roxane, Mak, Raymond, Loh, James, Kanani, Amin, Nowak, Dominik A., Keith, Paul K., Pannozzo, Daniel, Lima, Hermenio C., Pham, Diana, Pham, Hoang, Alvarez, Gonzalo G., Bencze, Istvan T., Sharma, Krishna B., Smith, Mark, Aaron, Shawn, Block, Jennifer, Keays, Tara, Leech, Judith, Schneidermen, David, Cameron, Jodi, Forgie, Jennifer, Ring, Alicia, O’Quinn, John W., Santucci, Stephanie, Yang, William H., Gaudet, Ena, Voisin, Mathew R., Borici-Mazi, Rozita, Vostretsova, Kateryna, Stark, Donald F., Yeboah, Elizabeth, Martin-Rhee, Michelle, Gula, Cheryl, Cheng, Clare, Paltser, Geoff, Dery, Alizée, Clarke, Ann, Nadeau, Kari, Harada, Laurie, Weatherall, Kimberley, Greenwood, Celia, Daley, Denise, Asai, Yuka, Ben-Shoshan, Moshe, Ling, Ling, Ospina, Maria B., Protudjer, Jennifer L. P., Vetander, Mirja, van Hage, Marianne, Olén, Ola, Wickman, Magnus, Bergström, Anna, Teoh, Timothy, Mill, Christopher, Wong, Tiffany

“…A1 Role of fibrocytes in allergic rhinitis Marie-Ève Côté, Marie-Ève Boulay, Sophie Plante, Jamila Chakir, Louis-Philippe Boulet A2 Patterns of aeroallergens…”
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Allergen-induced fluctuation in CC chemokine receptor 3 expression on bone marrow CD34(+) cells from asthmatic subjects: Significance for mobilization of haemopoietic progenitor by Sehmi, Roma, Dorman, Sandra, Baatjes, Adrian, Watson, Rick

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The effect of desloratadine on eosinophil/basophil progenitors and other inflammatory markers in seasonal allergic rhinitis: A placebo-controlled randomized study by Cyr, Michael M, Baatjes, Adrian J, Hayes, Lisa M, Crawford, Lynn, Denburg, Judah A

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