Search Results - "Baarends, WM"

DNA repair mechanisms and gametogenesis by Baarends, WM, van der Laan, R, Grootegoed, JA

“…In mammals, there is a complex and intriguing relationship between DNA repair and gametogenesis. DNA repair mechanisms are involved not only in the repair of…”
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Mouse Sycp1 functions in synaptonemal complex assembly, meiotic recombination, and XY body formation by de Vries, Femke A T, de Boer, Esther, van den Bosch, Mike, Baarends, Willy M, Ooms, Marja, Yuan, Li, Liu, Jian-Guo, van Zeeland, Albert A, Heyting, Christa, Pastink, Albert

“…In meiotic prophase, synaptonemal complexes (SCs) closely appose homologous chromosomes (homologs) along their length. SCs are assembled from two axial…”
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SPO11-independent DNA repair foci and their role in meiotic silencing by Carofiglio, Fabrizia, Inagaki, Akiko, de Vries, Sandra, Wassenaar, Evelyne, Schoenmakers, Sam, Vermeulen, Christie, van Cappellen, Wiggert A, Sleddens-Linkels, Esther, Grootegoed, J Anton, Te Riele, Hein P J, de Massy, Bernard, Baarends, Willy M

“…In mammalian meiotic prophase, the initial steps in repair of SPO11-induced DNA double-strand breaks (DSBs) are required to obtain stable homologous chromosome…”
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Silencing of Unpaired Chromatin and Histone H2A Ubiquitination in Mammalian Meiosis by Baarends, Willy M., Wassenaar, Evelyne, van der Laan, Roald, Hoogerbrugge, Jos, Sleddens-Linkels, Esther, Hoeijmakers, Jan H. J., de Boer, Peter, Grootegoed, J. Anton

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Differential Contributions of Mammalian Rad54 Paralogs to Recombination, DNA Damage Repair, and Meiosis by Wesoly, Joanna, Agarwal, Sheba, Sigurdsson, Stefan, Bussen, Wendy, Van Komen, Stephen, Qin, Jian, van Steeg, Harry, van Benthem, Jan, Wassenaar, Evelyne, Baarends, Willy M., Ghazvini, Mehrnaz, Tafel, Agnieszka A., Heath, Helen, Galjart, Niels, Essers, Jeroen, Grootegoed, J. Anton, Arnheim, Norman, Bezzubova, Olga, Buerstedde, Jean-Marie, Sung, Patrick, Kanaar, Roland

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The rat androgen receptor gene promoter by Baarends, W M, Themmen, A P, Blok, L J, Mackenbach, P, Brinkmann, A O, Meijer, D, Faber, P W, Trapman, J, Grootegoed, J A

“…The androgen receptor (AR) is activated upon binding of testosterone or dihydrotestosterone and exerts regulatory effects on gene expression in androgen target…”
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Targeted inactivation of mouse RAD52 reduces homologous recombination but not resistance to ionizing radiation by Rijkers, T, Van Den Ouweland, J, Morolli, B, Rolink, A G, Baarends, W M, Van Sloun, P P, Lohman, P H, Pastink, A

“…The RAD52 epistasis group is required for recombinational repair of double-strand breaks (DSBs) and shows strong evolutionary conservation. In Saccharomyces…”
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The Ubiquitin-Conjugating DNA Repair Enzyme HR6A Is a Maternal Factor Essential for Early Embryonic Development in Mice by Roest, Henk P., Baarends, Willy M., de Wit, Jan, van Klaveren, Jan W., Wassenaar, Evelyne, Hoogerbrugge, Jos W., van Cappellen, Wiggert A., Hoeijmakers, Jan H. J., Grootegoed, J. Anton

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Histone Ubiquitination and Chromatin Remodeling in Mouse Spermatogenesis by Baarends, Willy M, Hoogerbrugge, Jos W, Roest, Henk P, Ooms, Marja, Vreeburg, Jan, Hoeijmakers, Jan H.J, Grootegoed, J.Anton

“…Male infertility inHR6Bknockout mice is associated with impairment of spermatogenesis. TheHR6Bgene is a mammalian, autosomal homolog of theSaccharomyces…”
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Mutations that affect meiosis in male mice influence the dynamics of the mid-preleptotene and bouquet stages by Liebe, B., Petukhova, G., Barchi, M., Bellani, M., Braselmann, H., Nakano, T., Pandita, T.K., Jasin, M., Fornace, A., Meistrich, M.L., Baarends, W.M., Schimenti, J., de Lange, T., Keeney, S., Camerini-Otero, R.D., Scherthan, H.

“…Meiosis pairs and segregates homologous chromosomes and thereby forms haploid germ cells to compensate the genome doubling at fertilization. Homologue pairing…”
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Anti-müllerian hormone and anti-müllerian hormone type II receptor messenger ribonucleic acid expression in rat ovaries during postnatal development, the estrous cycle, and gonadotropin-induced follicle growth by Baarends, W M, Uilenbroek, J T, Kramer, P, Hoogerbrugge, J W, van Leeuwen, E C, Themmen, A P, Grootegoed, J A

“…During fetal development, anti-müllerian hormone (AMH) is produced only by Sertoli cells, but postnatally, granulosa cells also produce this peptide…”
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Loss of HR6B Ubiquitin-Conjugating Activity Results in Damaged Synaptonemal Complex Structure and Increased Crossing-Over Frequency during the Male Meiotic Prophase by Baarends, Willy M., Wassenaar, Evelyne, Hoogerbrugge, Jos W., van Cappellen, Gert, Roest, Henk P., Vreeburg, Jan, Ooms, Marja, Hoeijmakers, Jan H. J., Grootegoed, J. Anton

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Inactivation of the HR6B Ubiquitin-Conjugating DNA Repair Enzyme in Mice Causes Male Sterility Associated with Chromatin Modification by Roest, H.P, van Klaveren, J, de Wit, J, van Gurp, C.G, Koken, M.H.M, Vermey, M, van Roijen, J.H, Hoogerbrugge, J.W, Vreeburg, J.T.M, Baarends, W.M, Bootsma, D, Grootegoed, J.A, Hoeijmakers, J.H.J

“…The ubiquitin-conjugating yeast enzyme RAD6 and its human homologs hHR6A and hHR6B are implicated in postreplication repair and damage-induced mutagenesis. The…”
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Dynamic localization of human RAD18 during the cell cycle and a functional connection with DNA double-strand break repair by Inagaki, Akiko, van Cappellen, Wiggert A., van der Laan, Roald, Houtsmuller, Adriaan B., Hoeijmakers, Jan H.J., Grootegoed, J. Anton, Baarends, Willy M.

“…The ubiquitin ligase RAD18 is involved in different DNA repair processes. Here, we show that in G1 phase, human RAD18 accumulates in a few relatively large…”
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Molecular and cellular mechanisms in spermatogenesis by Grootegoed, J.Anton, Siep, Michel, Baarends, Willy M.

“…Mammalian spermatogenesis shows a strict control of many specific molecular and cellular events. This control involves Sertoli cell–germ cell interaction, as…”
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Basic helix–loop–helix transcription factor Tcfl5 interacts with the Calmegin gene promoter in mouse spermatogenesis by Siep, Michel, Sleddens-Linkels, Esther, Mulders, Sabine, van Eenennaam, Hans, Wassenaar, Evelyne, Van Cappellen, Wiggert A., Hoogerbrugge, Jos, Grootegoed, J. Anton, Baarends, Willy M.

“…In mouse spermatogenesis, differentiating germ line cells initiate expression of specific genes at subsequent developmental steps. The Calmegin (Clgn) gene is…”
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The ubiquitin system in gametogenesis by Baarends, Willy M., Roest, Henk P., Grootegoed, J.Anton

“…Ubiquitin is a ubiquitous and highly conserved protein of 76 amino acid residues, that can be covalently attached to cellular acceptor proteins. The attachment…”
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Specific aspects of the ubiquitin system in spermatogenesis by Baarends, W M, van der Laan, R, Grootegoed, J A

“…The ubiquitin system is involved in numerous cellular processes, regulating the amounts and/or activities of specific proteins through posttranslational…”
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Chromatin dynamics in the male meiotic prophase by Baarends, W M, Grootegoed, J A

“…During the male meiotic prophase in mouse and man, pairing and recombination of homologous chromosomes is accompanied by changes in chromatin structure. In…”
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A novel member of the transmembrane serine/threonine kinase receptor family is specifically expressed in the gonads and in mesenchymal cells adjacent to the mullerian duct by BAARENDS, W. M, VAN HELMOND, M. J. L, THEMMEN, A. P. N, GROOTEGOED, J, POST, M, VAN DER SCHOOT, P. J. C. M, HOOGERBRUGGE, J. W, DE WINTER, J. P, UILENBROEK, J. T. J, KARELS, B, WILMING, L. G, MEIJERS, J. H. C

“…The activin and TGF-beta type II receptors are members of a separate subfamily of transmembrane receptors with intrinsic protein kinase activity, which also…”
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