Search Results - "Baamonde, Ana"
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Spinal CCL2 and microglial activation are involved in paclitaxel-evoked cold hyperalgesia
Published in Brain research bulletin (01-06-2013)“…Highlights • We study CCR2 and CCL2 involvement in paclitaxel-evoked cold hyperalgesia in mice. • The i.t. injection of a CCR2 antagonist or a CCL2 antibody…”
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A low pKa ligand inhibits cancer-associated pain in mice by activating peripheral mu-opioid receptors
Published in Scientific reports (29-10-2020)“…The newly designed fentanyl derivative [( ±)-N-(3-fluoro-1-phenethylpiperidine-4-yl)-N-phenyl propionamide] (NFEPP) was recently shown to produce analgesia…”
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Involvement of CC Chemokine Receptor 1 and CCL3 in Acute and Chronic Inflammatory Pain in Mice
Published in Basic & clinical pharmacology & toxicology (01-07-2016)“…Chemokines are chemotactic cytokines whose involvement in nociceptive processing is being increasingly recognized. Based on the previous description of the…”
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Topical l -Menthol for Postradiotherapy Neuropathic Pain: A Case Report
Published in Journal of pain and symptom management (01-09-2015)Get full text
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Metalloproteinase MT5-MMP is an essential modulator of neuro-immune interactions in thermal pain stimulation
Published in Proceedings of the National Academy of Sciences - PNAS (22-09-2009)“…Peripheral interactions between nociceptive fibers and mast cells contribute to inflammatory pain, but little is known about mechanisms mediating neuro-immune…”
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Analgesic effects evoked by a CCR2 antagonist or an anti-CCL2 antibody in inflamed mice
Published in Fundamental & clinical pharmacology (01-06-2016)“…Chemokine CCL2, also known as monocyte chemoattractant protein‐1 (MCP‐1), is a molecule that in addition to its well‐established role in chemotaxis can also…”
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Unilateral hot plate test: a simple and sensitive method for detecting central and peripheral hyperalgesia in mice
Published in Journal of neuroscience methods (15-01-2002)“…The application of thermal noxious stimuli forms the basis of some widely used tests to detect either hyperalgesic or analgesic reactions. In the classical hot…”
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Involvement of Gi/o proteins and GIRK channels in the potentiation of morphine-induced spinal analgesia in acutely inflamed mice
Published in Naunyn-Schmiedeberg's archives of pharmacology (2010)“…The analgesic efficacy of opiates can be enhanced in inflammatory states due to peripheral and spinal alterations. We describe here that the analgesic effect…”
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A Role for Tachykinins in Female Mouse and Rat Reproductive Function
Published in Biology of reproduction (01-09-2003)“…Tachykinins may be involved in reproduction. A reverse transcription-polymerase chain reaction assay was used to analyze the expression of tachykinins and…”
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The analgesic effect induced by capsaicin is enhanced in inflammatory states
Published in Life sciences (1973) (14-05-2004)“…Agonists of the vanilloid receptor type 1 (VR1), such as capsaicin, induce an analgesic effect following an initial excitatory response. It has been…”
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Experiences and reflections about behavioral pain assays in laboratory animals
Published in Journal of neuroscience methods (15-02-2023)“…Pharmacological assays based on the measurement of nociceptive responses in laboratory animals are a fundamental tool to assess analgesic strategies. During…”
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Nociceptive reaction and thermal hyperalgesia induced by local ET-1 in mice: a behavioral and Fos study
Published in Naunyn-Schmiedeberg's archives of pharmacology (01-01-2003)“…The peptide endothelin-1 (ET-1) has been involved in nociception independently of its vasoconstrictor effects. We have studied the direct nociceptive behavior…”
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Involvement of CD4+ and CD8+ T-lymphocytes in the modulation of nociceptive processing evoked by CCL4 in mice
Published in Life sciences (1973) (15-02-2022)“…To explore the mechanisms involved in the transformation of analgesia produced by low doses of CCL4 (pg/kg) to hyperalgesia when higher doses (ng/kg) are…”
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Involvement of endogenous endothelins in thermal and mechanical inflammatory hyperalgesia in mice
Published in Naunyn-Schmiedeberg's archives of pharmacology (01-02-2004)Get full text
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Hyperalgesic Effect Evoked by il-16 and its Participation in Inflammatory Hypernociception in Mice
Published in Journal of neuroimmune pharmacology (17-08-2024)“…The systemic administration of interleukin-16 (IL-16, 3–30 ng/kg) induced thermal hyperalgesia in mice, that was prevented by the acute injection of an…”
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The Systemic Administration of the Chemokine CCL1 Evokes Thermal Analgesia in Mice Through the Activation of the Endocannabinoid System
Published in Cellular and molecular neurobiology (01-11-2019)“…Apart from its involvement in immune functions, the chemokine CCL1 can participate in the modulation of nociceptive processing. Previous studies have…”
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Dual dose-related effects evoked by CCL4 on thermal nociception after gene delivery or exogenous administration in mice
Published in Biochemical pharmacology (01-05-2020)“…[Display omitted] •CCL4 gene delivery provokes long-lasting hyperalgesia followed by analgesia in mice.•Low doses of CCL4 (pg/kg) evoke analgesia but higher…”
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Involvement of glutamate NMDA and AMPA receptors, glial cells and IL-1β in the spinal hyperalgesia evoked by the chemokine CCL2 in mice
Published in Neuroscience letters (20-09-2011)“…► CCL2 produces spinal hyperalgesia in mice. ► CCR2, AMPA and NMDA receptor antagonists inhibit it. ► Astroglia and microglia activation seems involved. ►…”
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Kappa‐opioid receptor‐mediated thermal analgesia evoked by the intrathecal administration of the chemokine CCL1 in mice
Published in Fundamental & clinical pharmacology (01-12-2021)“…Background The chemokine CC motif ligand 1 (CCL1) participates in immune cell recruitment and, as other chemokines, is also involved in nociceptive processing…”
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The Chemokine CCL4 (MIP-1β) Evokes Antinociceptive Effects in Mice: a Role for CD4+ Lymphocytes and Met-Enkephalin
Published in Molecular neurobiology (01-03-2019)“…In the present study, we characterize the antinociceptive effects produced by the chemokine CCL4 in mice. The intraplantar administration of very low doses of…”
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