Search Results - "Baak, Jan P A"
-
1
Major bioactive chemical compounds in Astragali Radix samples from different vendors vary greatly
Published in PloS one (07-07-2021)“…The worldwide traditional Chinese medicine (TCM) herbs sales figures have increased considerably to 50 billion US$ (2018). Astragali Radix (AR) is amongst the…”
Get full text
Journal Article -
2
Proliferation and immunohistochemistry for p53, CD25 and CK20 in predicting prognosis of non-muscle invasive papillary urothelial carcinomas
Published in PloS one (26-01-2024)“…Non-muscle invasive papillary urothelial carcinoma is a prevalent disease with a high recurrence tendency. Good prognostic and reproducible biomarkers for…”
Get full text
Journal Article -
3
Supersaturation and Precipitation Applicated in Drug Delivery Systems: Development Strategies and Evaluation Approaches
Published in Molecules (Basel, Switzerland) (27-02-2023)“…Supersaturation is a promising strategy to improve gastrointestinal absorption of poorly water-soluble drugs. Supersaturation is a metastable state and…”
Get full text
Journal Article -
4
Comparison of the effect of different techniques for measurement of Ki67 proliferation on reproducibility and prognosis prediction accuracy in breast cancer
Published in Histopathology (01-12-2012)“…Gudlaugsson E, Skaland I, Janssen E A M, Smaaland R, Shao Z, Malpica A, Voorhorst F & Baak J P A (2012) Histopathology Comparison of the effect of different…”
Get full text
Journal Article -
5
Mitotic activity index and CD25+ lymphocytes predict risk of stage progression in non-muscle invasive bladder cancer
Published in PloS one (02-06-2020)“…In urothelial cell type non-muscle invasive urinary bladder carcinoma, TNM stage and WHO grade are widely used to classify patients into low and high-risk…”
Get full text
Journal Article -
6
MiR-18a and miR-18b are expressed in the stroma of oestrogen receptor alpha negative breast cancers
Published in BMC cancer (05-05-2020)“…Previously, we have shown that miR-18a and miR-18b gene expression strongly correlates with high proliferation, oestrogen receptor -negativity (ER ),…”
Get full text
Journal Article -
7
Validation of expression patterns for nine miRNAs in 204 lymph-node negative breast cancers
Published in PloS one (07-11-2012)“…Although lymph node negative (LN-) breast cancer patients have a good 10-years survival (∼85%), most of them still receive adjuvant therapy, while only some…”
Get full text
Journal Article -
8
Validation study of MARCKSL1 as a prognostic factor in lymph node-negative breast cancer patients
Published in PloS one (11-03-2019)“…Protein expression of Myristoylated alanine-rich C kinase substrate like-1 (MARCKSL1) has been identified as a prognostic factor in lymph-node negative (LN-)…”
Get full text
Journal Article -
9
Metabolic consequences of perioperative oral carbohydrates in breast cancer patients - an explorative study
Published in BMC cancer (04-12-2019)“…The metabolic consequences of preoperative carbohydrate load in breast cancer patients are not known. The present explorative study investigated the systemic…”
Get full text
Journal Article -
10
Reproducibility and prognostic value of WHO1973 and WHO2004 grading systems in TaT1 urothelial carcinoma of the urinary bladder
Published in PloS one (07-01-2014)“…European treatment guidelines of TaT1 urinary bladder urothelial carcinomas depend highly on stage and WHO1973-grade but grading reproducibility is wanting…”
Get full text
Journal Article -
11
Prognostic value and reproducibility of different microscopic characteristics in the WHO grading systems for pTa and pT1 urinary bladder urothelial carcinomas
Published in Diagnostic pathology (14-08-2019)“…European treatment guidelines for pTa and pT1 urinary bladder urothelial carcinoma depend highly on stage and WHO-grade. Both the WHO73 and the WHO04 grading…”
Get full text
Journal Article -
12
Can proliferation biomarkers reliably predict recurrence in World Health Organization 2003 defined endometrial stromal sarcoma, low grade?
Published in PloS one (11-10-2013)“…An estimated 1500-3000 invasive Endometrial Stromal Sarcomas (ESS) cases annually occur worldwide. Before 2003, ESS was divided as low and high grade ESS based…”
Get full text
Journal Article -
13
Prognostic value of gene signatures and proliferation in lymph-node-negative breast cancer
Published in PloS one (05-03-2014)“…The overall survival rate is good for lymph-node-negative breast cancer patients, but they still suffer from serious over- and some undertreatments. Prognostic…”
Get full text
Journal Article -
14
Proliferation is the strongest prognosticator in node-negative breast cancer: significance, error sources, alternatives and comparison with molecular prognostic markers
Published in Breast cancer research and treatment (01-05-2009)“…Independent studies have shown that in node negative breast cancer patients less than 71 years, the proliferation marker mitotic activity index (MAI) is the…”
Get full text
Journal Article -
15
Validating the prognostic value of proliferation measured by Phosphohistone H3 (PPH3) in invasive lymph node-negative breast cancer patients less than 71 years of age
Published in Breast cancer research and treatment (01-03-2009)“…We validated and compared the prognostic value of the proliferation marker phosphohistone H3 (PPH3) with classical variables in 241 T₁₋₂N₀M₀ breast cancer…”
Get full text
Journal Article -
16
The prognostic value of MARCKS-like 1 in lymph node-negative breast cancer
Published in Breast cancer research and treatment (01-09-2012)“…There is a need for new biomarkers to more correctly identify node-negative breast cancer patients with a good or bad prognosis. Myristoylated alanine-rich C…”
Get full text
Journal Article -
17
Consistent condom use increases the regression rate of cervical intraepithelial neoplasia 2-3
Published in PloS one (13-09-2012)“…Cervical intraepithelial neoplasia grades 2-3 (CIN2-3) are usually treated by cone excision, although only 30% progress to cancer and 6-50% regress…”
Get full text
Journal Article -
18
Clinical and Biological Interpretation of Survival Curves of Cancer Patients, Exemplified With Stage IV Non-Small Cell Lung Cancers With Long Follow-up
Published in Frontiers in oncology (02-02-2022)“…Worldwide, 18.1 million new invasive cancers and 9.9 million cancer deaths occurred in 2020. Lung cancer is the second most frequent (11.4%) and, with 1.8…”
Get full text
Journal Article -
19
"How Long Have I Got?" in Stage IV NSCLC Patients With at Least 3 Months Up to 10 Years Survival, Accuracy of Long-, Intermediate-, and Short-Term Survival Prediction Is Not Good Enough to Answer This Question
Published in Frontiers in oncology (21-12-2021)“…Most lung cancer patients worldwide [stage IV nonsmall cell lung cancer (NSCLC)] have a poor survival: 25%-30% die <3 months. Yet, of those surviving…”
Get full text
Journal Article -
20
Influence of pre-operative oral carbohydrate loading vs. standard fasting on tumor proliferation and clinical outcome in breast cancer patients ─ a randomized trial
Published in BMC cancer (08-11-2019)“…Conflicting results have been reported on the influence of carbohydrates in breast cancer. To determine the influence of pre-operative per-oral carbohydrate…”
Get full text
Journal Article