Search Results - "Bárcena, José Antonio"

A conserved cysteine‐based redox mechanism sustains TFEB/HLH‐30 activity under persistent stress by Martina, José A, Guerrero‐Gómez, David, Gómez‐Orte, Eva, Antonio Bárcena, José, Cabello, Juan, Miranda‐Vizuete, Antonio, Puertollano, Rosa

“…Mammalian TFEB and TFE3, as well as their ortholog in Caenorhabditis elegans HLH‐30, play an important role in mediating cellular response to a variety of…”
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General Statistical Framework for Quantitative Proteomics by Stable Isotope Labeling by Navarro, Pedro, Trevisan-Herraz, Marco, Bonzon-Kulichenko, Elena, Núñez, Estefanía, Martínez-Acedo, Pablo, Pérez-Hernández, Daniel, Jorge, Inmaculada, Mesa, Raquel, Calvo, Enrique, Carrascal, Montserrat, Hernáez, María Luisa, García, Fernando, Bárcena, José Antonio, Ashman, Keith, Abian, Joaquín, Gil, Concha, Redondo, Juan Miguel, Vázquez, Jesús

“…The combination of stable isotope labeling (SIL) with mass spectrometry (MS) allows comparison of the abundance of thousands of proteins in complex mixtures…”
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Tumoral Malignancy Decreases Coupled with Higher ROS and Lipid Peroxidation in HCT116 Colon Cancer Cells upon Loss of PRDX6 by Lagal, Daniel J, Montes-Osuna, Antonio M, Ortiz-Olivencia, Alberto, Arribas-Parejas, Candela, Ortiz-Alcántara, Ángel, Pescuezo-Castillo, Cristina, Bárcena, José Antonio, Padilla, Carmen Alicia, Requejo-Aguilar, Raquel

“…Peroxiredoxin 6 (PRDX6) is an atypical member of the peroxiredoxin family that presents not only peroxidase but also phospholipase A2 and…”
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Shotgun redox proteomics identifies specifically modified cysteines in key metabolic enzymes under oxidative stress in Saccharomyces cerevisiae by McDonagh, Brian, Ogueta, Samuel, Lasarte, Guillermo, Padilla, C. Alicia, Bárcena, José Antonio

“…Postranslational redox modification of thiol groups can form the molecular basis of antioxidative protection and redox control. We have implemented a shotgun…”
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Thioredoxin Downregulation Enhances Sorafenib Effects in Hepatocarcinoma Cells by López-Grueso, María José, González, Raúl, Muntané, Jordi, Bárcena, José Antonio, Padilla, C. Alicia

“…Sorafenib is the first-line recommended therapy for patients with advanced hepatocarcinoma (HCC) in de-differentiation stage (presenting epithelial–mesenchymal…”
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Peroxiredoxin 6 Down-Regulation Induces Metabolic Remodeling and Cell Cycle Arrest in HepG2 Cells by López Grueso, María José, Tarradas Valero, Rosa María, Carmona-Hidalgo, Beatriz, Lagal Ruiz, Daniel José, Peinado, José, McDonagh, Brian, Requejo Aguilar, Raquel, Bárcena Ruiz, José Antonio, Padilla Peña, Carmen Alicia

“…Peroxiredoxin 6 (Prdx6) is the only member of 1-Cys subfamily of peroxiredoxins in human cells. It is the only Prdx acting on phospholipid hydroperoxides…”
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Deficiency of Parkinson’s Related Protein DJ-1 Alters Cdk5 Signalling and Induces Neuronal Death by Aberrant Cell Cycle Re-entry by López-Grueso, María José, Padilla, Carmen Alicia, Bárcena, José Antonio, Requejo-Aguilar, Raquel

“…DJ-1 is a multifunctional protein involved in Parkinson disease (PD) that can act as antioxidant, molecular chaperone, protease, glyoxalase, and…”
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Selection of thiol- and disulfide-containing proteins of Escherichia coli on activated thiol-Sepharose by Hu, Wentao, Tedesco, Sara, McDonagh, Brian, Bárcena, José Antonio, Keane, Catherine, Sheehan, David

“…Activated thiol-Sepharose (ATS) facilitates selection of thiol-containing proteins. In control- and menadione-treated Escherichia coli, batch selection…”
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Biosynthetic and Iron Metabolism Is Regulated by Thiol Proteome Changes Dependent on Glutaredoxin-2 and Mitochondrial Peroxiredoxin-1 in Saccharomyces cerevisiae by McDonagh, Brian, Padilla, C. Alicia, Pedrajas, José Rafael, Bárcena, José Antonio

“…Redoxins are involved in maintenance of thiol redox homeostasis, but their exact sites of action are only partly known. We have applied a combined redox…”
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Thiol Redox Sensitivity of Two Key Enzymes of Heme Biosynthesis and Pentose Phosphate Pathways : Uroporphyrinogen Decarboxylase and Transketolase by McDonagh, Brian, Pedrajas, José Rafael, Padilla, C. Alicia, Bárcena, José Antonio

“…Uroporphyrinogen decarboxylase (Hem12p) and transketolase (Tkl1p) are key mediators of two critical processes within the cell, heme biosynthesis, and the…”
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Redox proteomics by Sheehan, David, McDonagh, Brian, Bárcena, José Antonio

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Changes in the Proteome of Functional and Regressing Corpus Luteum During Pregnancy and Lactation in the Rat1 by González-Fernández, Raquel, Martínez-Galisteo, Emilia, Gaytán, Francisco, Bárcena, JoséAntonio, Sánchez-Criado, JoséEugenio

“…The corpus luteum (CL) is an exquisitely regulated transitory endocrine gland necessary for the onset and maintenance of pregnancy in mammals. Most of the data…”
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Report on the First Congress of the Spanish Proteomics Society by Jorrín, Jesús, Bárcena, José Antonio, Moreno, Angela, Calvete, Juan J.

“…This report describes the first congress of the Spanish Proteomics Society (SEProt) and the Foundation Meeting of the European Proteomics Association (EuPA),…”
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Knockout of PRDX6 induces mitochondrial dysfunction and cell cycle arrest at G2/M in HepG2 hepatocarcinoma cells by López-Grueso, María José, Lagal, Daniel José, García-Jiménez, Álvaro Fernando, Tarradas, Rosa María, Carmona-Hidalgo, Beatriz, Peinado, José, Requejo-Aguilar, Raquel, Bárcena, José Antonio, Padilla, Carmen Alicia

“…Peroxiredoxin 6 (PRDX6) has been associated with tumor progression and cancer metastasis. Its acting on phospholipid hydroperoxides and its phospholipase-A2…”
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Glutathione Is the Resolving Thiol for Thioredoxin Peroxidase Activity of 1-Cys Peroxiredoxin Without Being Consumed During the Catalytic Cycle by Pedrajas, José Rafael, McDonagh, Brian, Hernández-Torres, Francisco, Miranda-Vizuete, Antonio, González-Ojeda, Raúl, Martínez-Galisteo, Emilia, Padilla, C Alicia, Bárcena, José Antonio

“…A three-step catalytic cycle is common to all peroxiredoxins (Prxs), despite structural and kinetic differences. The second step in 1-Cys type Prxs is a matter…”
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OUT OF CÓRDOBA by Bárcena, José Antonio, Calvete, Juan José, Moreno-López, Angela, Jorrín-Novo, Jesús V.

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Glutaredoxin participates in the reduction of peroxides by the mitochondrial 1-CYS peroxiredoxin in Saccharomyces cerevisiae by Pedrajas, José Rafael, Padilla, C Alicia, McDonagh, Brian, Bárcena, José Antonio

“…The mechanism for regeneration of the active-site "peroxidatic" cysteine in 1-Cys peroxiredoxins is a matter of debate. Saccharomyces cerevisiae Prx1 is a…”
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Regulation of Nrf2 signaling during the antitumoral activity of Sorafenib in hepatoma cells by González, Raúl, Rodríguez-Hernández, María A., José López-Grueso, María, Isabel Rojo, Ana, Navarro-Villarán, Elena, Padillo, Javier, Antonio Bárcena, José, Cuadrado, Antonio, Alicia Padilla, Carmen, Muntane, Jordi

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P 222 - Regulation of Nrf2 signaling during the antitumoral activity of Sorafenib in hepatoma cells by González, Raúl, Rodríguez-Hernández, María A., José López-Grueso, María, Isabel Rojo, Ana, Navarro-Villarán, Elena, Padillo, Javier, Antonio Bárcena, José, Cuadrado, Antonio, Alicia Padilla, Carmen, Muntane, Jordi

“…Sorafenib is the accepted treatment for patients in advanced stage of hepatocarcinoma. Goal: The study evaluated the regulation of the endoplasmic reticulum…”
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Improved integrative analysis of the thiol redox proteome using filter-aided sample preparation by Bonzon-Kulichenko, Elena, Camafeita, Emilio, López, Juan Antonio, Gómez-Serrano, María, Jorge, Inmaculada, Calvo, Enrique, Núñez, Estefanía, Trevisan-Herraz, Marco, Bagwan, Navratan, Bárcena, José Antonio, Peral, Belén, Vázquez, Jesús

“…[Display omitted] Changes in the oxidation state of protein Cys residues are involved in cell signalling and play a key role in a variety of pathophysiological…”
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