Search Results - "BYRNE, Maria M"

The clinical management of hyperglycemia in pregnancy complicated by maturity-onset diabetes of the young by Bacon, Siobhan, MD, Schmid, Jasmin, MSc, McCarthy, Ailbhe, RGN, Edwards, Jackie, RGN, RM, Pg Dip Diabetes, Fleming, Aileen, RGN, Kinsley, Brendan, MD, Firth, Richard, MD, Byrne, Bridgette, MD, Gavin, Claire, MD, Byrne, Maria M., MD

“…Objective Women with maturity-onset diabetes of the young (MODY) are often first identified and diagnosed with diabetes during pregnancy. Genetics and…”
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Case report: Glycaemic management and pregnancy outcomes in a woman with an insulin receptor mutation, p.Met1180Lys by Crowley, Mairéad T, Goulden, Eirena, Sanchez-Lechuga, Begona, Fleming, Aileen, Kennelly, Maria, McDonnell, Ciara, Byrne, Maria M

“…Heterozygous insulin receptor mutations (INSR) are associated with insulin resistance, hyperglycaemia and hyperinsulinaemic hypoglycaemia in addition to…”
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Metastatic medullary thyroid carcinoma presenting as ectopic Cushing’s syndrome by Forde, Hannah E, Mehigan-Farrelly, Niamh, Ryan, Katie, Moran, Tom, Greally, Megan, Duffy, Austin G, Byrne, Maria M

“…Summary A 41-year-old male presented to the Emergency Department with a 6-month history of back and hip pain. Skeletal survey revealed bilateral pubic rami…”
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An evolving spectrum of diabetes in a woman with GCK-MODY by Garrahy, Aoife, Mijares Zamuner, Matilde Bettina, Byrne, Maria M

“…Summary Coexistence of autoimmune diabetes and maturity-onset diabetes of the young (MODY) is rare. We report the first case of coexisting latent autoimmune…”
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Primary hyperparathyroidism in a patient with familial hypocalciuric hypercalcaemia due to a novel mutation in the calcium-sensing receptor gene by Egan, Aoife M., Ryan, James, Aziz, Mardiana A., O’Dwyer, Tadhg P., Byrne, Maria M.

“…We describe the clinical and genetic findings in pedigree with a novel mutation in the calcium sensing receptor (CaSR) gene and the unusual coexistence of…”
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Circulating CD36 is reduced in HNF1A-MODY carriers by Bacon, Siobhan, Kyithar, Ma P, Schmid, Jasmin, Costa Pozza, Andre, Handberg, Aase, Byrne, Maria M

“…Premature atherosclerosis is a significant cause of morbidity and mortality in type 2 diabetes mellitus. Maturity onset diabetes of the young (MODY) accounts…”
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Successful Use of a GLP-1 Receptor Agonist as Add-on Therapy to Glibenclamide in a Young Adult With KCNJ11 Permanent Neonatal Diabetes by Crowley, Mairéad T, Roarty, Sarah, O'Shea, Helen, Hattersley, Andrew T, Byrne, Maria M

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Serum levels of pancreatic stone protein (PSP)/reg1A as an indicator of beta-cell apoptosis suggest an increased apoptosis rate in hepatocyte nuclear factor 1 alpha (HNF1A-MODY) carriers from the third decade of life onward by Bacon, Siobhan, Kyithar, Ma Peyh, Schmid, Jasmin, Rizvi, Syed R, Bonner, Caroline, Graf, Rolf, Prehn, Jochen Hm, Byrne, Maria M

“…Mutations in the transcription factor hepatocyte nuclear factor-1-alpha (HNF1A) result in the commonest type of maturity onset diabetes of the young (MODY)…”
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Letter to the Editor: “Alemtuzumab-Induced Thyroid Dysfunction Exhibits Distinctive Clinical and Immunological Features” by Garrahy, Aoife, Murphy, Nuala P, Byrne, Maria M

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Effects of hepatocyte nuclear factor-1A and -4A on pancreatic stone protein/regenerating protein and C-reactive protein gene expression: implications for maturity-onset diabetes of the young by Kyithar, Ma P, Bonner, Caroline, Bacon, Siobhan, Kilbride, Seán M, Schmid, Jasmin, Graf, Rolf, Prehn, Jochen H M, Byrne, Maria M

“…There is a significant clinical overlap between patients with hepatocyte nuclear factor (HNF)-1A and HNF4A maturity-onset diabetes of the young (MODY), two…”
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Circulating miR-330-3p in Late Pregnancy is Associated with Pregnancy Outcomes Among Lean Women with GDM by Pfeiffer, Shona, Sánchez-Lechuga, Begoña, Donovan, Paul, Halang, Luise, Prehn, Jochen H. M., Campos-Caro, Antonio, Byrne, Maria M., López-Tinoco, Cristina

“…Gestational Diabetes Mellitus (GDM) is characterised by insulin resistance accompanied by reduced beta-cell compensation to increased insulin demand, typically…”
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Evaluation of pregnancy outcomes in women with GCK‐MODY by López Tinoco, Cristina, Sánchez Lechuga, Begoña, Bacon, Siobhan, Colclough, Kevin, Ng, Nicholas, Wong, Eleanor, Goulden, Eirena L., Edwards, Jackie, Fleming, Aileen, Byrne, Bridgette, Byrne, Maria M.

“…Aims To determine the fetal and maternal outcomes in pregnant women with Glucokinase‐Maturity onset diabetes of the young (GCK‐MODY). Methods We studied the…”
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Acute presentation of a giant intrathyroidal parathyroid adenoma: a case report by Rutledge, Stephanie, Harrison, Michele, O'Connell, Martin, O'Dwyer, Tadhg, Byrne, Maria M

“…We report the case of a giant intrathyroidal parathyroid adenoma weighing 59 g in a young woman presenting acutely with severe hypercalcemia requiring…”
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MicroRNA-224 is Readily Detectable in Urine of Individuals with Diabetes Mellitus and is a Potential Indicator of Beta-Cell Demise by Bacon, Siobhán, Engelbrecht, Britta, Schmid, Jasmin, Pfeiffer, Shona, Gallagher, Ross, McCarthy, Ailbhe, Burke, Marie, Concannon, Caoimhín, Prehn, Jochen H M, Byrne, Maria M

“…MicroRNA (miRNA) are a class of non-coding, 19-25 nucleotide RNA critical for network-level regulation of gene expression. miRNA serve as paracrine signaling…”
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AMP-activated Protein Kinase Mediates Apoptosis in Response to Bioenergetic Stress through Activation of the Pro-apoptotic Bcl-2 Homology Domain-3-only Protein BMF by Kilbride, Seán M., Farrelly, Angela M., Bonner, Caroline, Ward, Manus W., Nyhan, Kristine C., Concannon, Caoimhín G., Wollheim, Claes B., Byrne, Maria M., Prehn, Jochen H.M.

“…Heterozygous loss-of-function mutations in the hepatocyte nuclear factor 1A (HNF1A) gene result in the pathogenesis of maturity-onset diabetes-of-the-young…”
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Sleepiness, performance, and neuroendocrine function during sleep deprivation: effects of exposure to bright light or exercise by Leproult, R, Van Reeth, O, Byrne, M M, Sturis, J, Van Cauter, E

“…The temporal profiles of subjective fatigue (as assessed by the Stanford Sleepiness Scale), of cognitive performance (on a digit symbol substitution test and a…”
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INS-1 Cells Undergoing Caspase-Dependent Apoptosis Enhance the Regenerative Capacity of Neighboring Cells by BONNER, Caroline, BACON, Siobhán, WOLLHEIM, Claes B, GRAF, Rolf, BYRNE, Maria M, PREHN, Jochen H. M, CONCANNON, Caoimhín G, RIZVI, Syed R, BAQUIE, Mathurin, FARRELLY, Angela M, KILBRIDE, Seán M, DUSSMANN, Heiko, WARD, Manus W, BOULANGER, Chantal M

“…In diabetes, β-cell mass is not static but in a constant process of cell death and renewal. Inactivating mutations in transcription factor 1 (tcf-1)/hepatocyte…”
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Bone Morphogenetic Protein 3 Controls Insulin Gene Expression and Is Down-regulated in INS-1 Cells Inducibly Expressing a Hepatocyte Nuclear Factor 1A–Maturity-onset Diabetes of the Young Mutation by Bonner, Caroline, Farrelly, Angela M., Concannon, Caoimhín G., Dussmann, Heiko, Baquié, Mathurin, Virard, Isabelle, Wobser, Hella, Kögel, Donat, Wollheim, Claes B., Rupnik, Marjan, Byrne, Maria M., König, Hans-Georg, Prehn, Jochen H.M.

“…Inactivating mutations in the transcription factor hepatocyte nuclear factor (HNF) 1A cause HNF1A–maturity-onset diabetes of the young (HNF1A-MODY), the most…”
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Rapamycin protects against dominant negative-HNF1A-induced apoptosis in INS-1 cells by Farrelly, Angela M., Kilbride, Seán M., Bonner, Caroline, Prehn, Jochen H. M., Byrne, Maria M.

“…HNF1A-maturity onset diabetes of the young (HNF1A-MODY) is caused by mutations in Hnf1a gene encoding the transcription factor hepatocyte nuclear factor 1alpha…”
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Altered insulin secretory responses to glucose in diabetic and nondiabetic subjects with mutations in the diabetes susceptibility gene MODY3 on chromosome 12 by BYRNE, M. M, STURIS, J, BELL, G. I, POLONSKY, K. S, MENZEL, S, YAMAGATA, K, FAJANS, S. S, DRONSFIELD, M. J, BAIN, S. C, HATTERSLEY, A. T, VELHO, G, FROGUEL, P

“…One form of maturity-onset diabetes of the young (MODY) results from mutations in a gene, designated MODY3, located on chromosome 12 in band q24. The present…”
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