Search Results - "BYERS, T. L"

Repair of DNA containing O6-alkylguanine by Pegg, A E, Byers, T L

“…O6-Alkylguanines, important DNA adducts formed by alkylating agents, can lead to mutations and to cell death unless repaired. The major pathway of repair…”
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Properties and physiological function of the polyamine transport system by Byers, T L, Pegg, A E

“…Polyamine transport was examined in Chinese hamster ovary (CHO) cells because of the unique potential these cells hold for utilizing genetic approaches to…”
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The role of hypusine depletion in cytostasis induced by S-adenosyl-L-methionine decarboxylase inhibition: new evidence provided by 1-methylspermidine and 1,12-dimethylspermine by Byers, T L, Lakanen, J R, Coward, J K, Pegg, A E

“…The abilities of the natural polyamines, spermidine and spermine, and of the synthetic analogues, 1-methylspermidine and 1,12-dimethylspermine, to reverse the…”
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Antitrypanosomal effects of polyamine biosynthesis inhibitors correlate with increases in Trypanosoma brucei brucei S-adenosyl-L-methionine by BYERS, T. L, BUSH, T. L, MCCANN, P. P, BITONTI, A. J

“…We reported recently that administration of ([(Z)-4-amino-2-butenyl]methylamino)-5'-deoxyadenosine (MDL 73811), an enzyme-activated irreversible inhibitor of…”
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Cure of Trypanosoma brucei brucei and Trypanosoma brucei rhodesiense infections in mice with an irreversible inhibitor of S-adenosylmethionine decarboxylase by Bitonti, A J, Byers, T L, Bush, T L, Casara, P J, Bacchi, C J, Clarkson, Jr, A B, McCann, P P, Sjoerdsma, A

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Effects of the S-adenosylmethionine decarboxylase inhibitor, 5'-{[(Z)-4-amino-2-butenyl]methylamino}-5'-deoxyadenosine, on cell growth and polyamine metabolism and transport in Chinese hamster ovary cell cultures by BYERS, T. L, WECHTER, R. S, REI-HUANG HU, PEGG, A. E

“…The regulation of polyamine transport and the roles of polyamine transport and synthesis in cell growth were investigated using cultured Chinese hamster ovary…”
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Uptake of the antitrypanosomal drug 5'-{[(Z)-4-amino-2-butenyl]methylamino}-5'-deoxyadenosine (MDL 73811) by the purine transport system of Trypanosoma brucei brucei by BYERS, T. L, CASARA, P, BITONTI, A. J

“…An irreversible inhibitor of S-adenosyl-L-methionine decarboxylase (AdoMetDC), 5′-([(Z)-4-amino-2-butenyl]methylamino)-5′-deoxyadenosine (MDL 73811), was found…”
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Regulation of polyamine transport in Chinese hamster ovary cells by Byers, T L, Pegg, A E

“…Control Chinese hamster ovary (CHO) cells and mutant CHO cells lacking ornithine decarboxylase activity (CHODC-) were used to study the regulation of polyamine…”
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Multiple pathways for uptake of paraquat, methylglyoxal bis(guanylhydrazone), and polyamines by Byers, T.L, Kameji, R, Rannels, D.E, Pegg, A.E

“…The uptake of polyamines, methylglyoxal bis(guanylhydrazone) (MGBG), and paraquat [N,N-dimethyl-4,4'-bipyridylium] into control Chinese hamster ovary (CHO)…”
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Expression of a human gene for polyamine transport in Chinese-hamster ovary cells by Byers, T L, Wechter, R, Nuttall, M E, Pegg, A E

“…A molecular-genetic approach towards isolating mammalian polyamine-transport genes and their encoded proteins was devised involving the production of…”
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Cytostasis induced in L1210 murine leukaemia cells by the S-adenosyl-L-methionine decarboxylase inhibitor 5'-{[(Z)-4-amino-2-butenyl]methylamino}-5'-deoxyadenosine may be due to hypusine depletion by BYERS, T. L, GANEM, B, PEGG, A. E

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bis(benzyl)polyamine analogues are substrates for a mammalian cell-transport system which is distinct from the polyamine-transport system by Byers, T L, Bitonti, A J, McCann, P P

“…Bis(benzyl)polyamine analogues (e.g. NN'-bis(3-[(phenylmethyl)amino]propyl)-1,8-diamino-octane [C6H5CH2NH-(CH2)3NH(CH2)8NH(CH2)3NHCH2C6H5]) have previously…”
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Mechanism of inactivation of human O6-alkylguanine-DNA alkyltransferase by O6-benzylguanine by Pegg, Anthony E, Boosalis, Michael, Samson, Leona, Moschel, Robert C, Byers, Timothy L, Swenn, Kristin, Dolan, M. Eileen

“…Human O6-alkylguanine-DNA alkyltransferase was rapidly inactivated by low concentrations of O6-benzylguanine, but the alkyltransferase from the Escherichia…”
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Cytostasis induced in L1210 murine leukaemia cells by the S-adenosyl-L-methionine decarboxylase inhibitor 5'-([(Z)-4-amino-2-butenyl]methylamino)-5'-deoxyadenosine may be due to hypusine depletion by Byers, T L, Ganem, B, Pegg, A E

“…The effects of inhibition of the capacity to form spermidine and spermine on cell growth were investigated using murine leukaemia L1210 cells and…”
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Surgical Treatment of an Intrastromal Epithelial Corneal Cyst by Mifflin, Mark D, Byers, Timothy L, Elliot, Richard, Hoffman, Robert

“…PURPOSE.To describe corneal intrastromal epithelial cysts and present a minimally invasive surgical technique successfully used to treat such a lesion…”
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Irreversible inhibition of S-adenosylmethionine decarboxylase in Plasmodium falciparum-infected erythrocytes: growth inhibition in vitro by Wright, P S, Byers, T L, Cross-Doersen, D E, McCann, P P, Bitonti, A J

“…Blocking spermidine and spermine synthesis in Plasmodium falciparum-infected erythrocytes with irreversible inhibitors of S-adenosylmethionine decarboxylase…”
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Uptake of the antitrypanosomal drug 5'-([(Z)-4-amino-2-butenyl]methylamino)-5'-deoxyadenosine (MDL 73811) by the purine transport system of Trypanosoma brucei brucei by Byers, T L, Casara, P, Bitonti, A J

“…An irreversible inhibitor of S-adenosyl-L-methionine decarboxylase (AdoMetDC), 5'-([(Z)-4-amino-2-butenyl]methylamino)-5'-deoxyadenosine (MDL 73811), was found…”
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Effects of the S-adenosylmethionine decarboxylase inhibitor, 5'-([(Z)-4-amino-2-butenyl]methylamino)-5'-deoxyadenosine, on cell growth and polyamine metabolism and transport in Chinese hamster ovary cell cultures by Byers, T L, Wechter, R S, Hu, R H, Pegg, A E

“…The regulation of polyamine transport and the roles of polyamine transport and synthesis in cell growth were investigated using cultured Chinese hamster ovary…”
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Effects of the S -adenosylmethionine decarboxylase inhibitor, 5′-{[(Z)-4-amino-2-butenyl]methylamino)-5′-deoxyadenosine, on cell growth and polyamine metabolism and transport in Chinese hamster ovary cell cultures by Byers, T L, Wechter, R S, Hu, R H, Pegg, A E

“…The regulation of polyamine transport and the roles of polyamine transport and synthesis in cell growth were investigated using cultured Chinese hamster ovary…”
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Effects of chronic 5′-{[( Z )-4-amino-2-butenyl]methylamino)-5′-deoxy- adenosine (AbeAdo) treatment on polyamine and eIF-5A metabolism in AbeAdo-sensitive and -resistant L1210 murine leukaemia cells by Byers, T L, Wiest, L, Wechter, R S, Pegg, A E

“…We have previously reported that prolonged chronic exposure to the S-adenosyl-L-methionine decarboxylase (AdoMetDC) inhibitor,…”
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