Search Results - "BUTOUR, Jean‐Luc"
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Isolation and structure of the endogenous agonist of opioid receptor-like ORL1 receptor
Published in Nature (London) (12-10-1995)“…The ORL1 receptor, an orphan receptor whose human and murine complementary DNAs have recently been characterized, structurally resembles opioid receptors and…”
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Recognition and activation of the opioid receptor-like ORL1 receptor by nociceptin, nociceptin analogs and opioids
Published in European journal of pharmacology (19-02-1997)“…Nociceptin, also known as orphanin FQ, was recently identified as the naturally occurring agonist of orphan opioid receptor-like ORL1 receptor (Meunier et al.,…”
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Agonist-independent localization of the NOP receptor in detergent-resistant membrane rafts
Published in Biochemical and biophysical research communications (17-12-2004)“…A lipid rafts/detergent-resistant membrane (DRM) fraction was prepared from recombinant HEK293 cells stably expressing the human NOP receptor fused to the…”
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ORL1, a novel member of the opioid receptor family: Cloning, functional expression and localization
Published in FEBS letters (14-03-1994)“…Selective PCR amplification of human and mouse genomic DNAs with oligonucleotides encoding highly conserved regions of the δ-opioid and somatostatin receptors…”
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Biophysical studies of the modification of DNA by antitumour platinum coordination complexes
Published in Biophysical chemistry (01-04-1990)“…Cisplatin (cis-diamminedichloroplatinum(II] is widely used in the treatment of various human tumours. A large body of experimental evidence indicates that the…”
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[Phe1ψ(CH2-NH)Gly2]nociceptin-(1-13)-NH2 is an agonist of the nociceptin (ORL1) receptor
Published in European journal of pharmacology (15-05-1998)“…[Phe1psi(CH2-NH)Gly2]nociceptin-(1-13)-NH2, a pseudopeptide analog of nociceptin, has been shown to be a selective 'antagonist' of the nociceptin receptor in…”
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Distinct mechanisms for activation of the opioid receptor-like 1 and kappa-opioid receptors by nociceptin and dynorphin A
Published in Molecular pharmacology (01-02-1999)“…To understand how two structurally analogous ligand-receptor systems, the nociceptin/opioid receptor-like 1 (ORL1) and dynorphin A/kappa-opioid receptor 1…”
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Differentiation of DNA-platinum complexes by fluorescence. The use of an intercalating dye as a probe
Published in European journal of biochemistry (01-09-1977)Get full text
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NMR Study of the Interaction of Platinum Salts with a Tetrapeptide Containing Cysteinyl Residues
Published in Inorganic chemistry (01-10-1994)Get full text
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Replacement of Gln280 by His in TM6 of the human ORL1 receptor increases affinity but reduces intrinsic activity of opioids
Published in FEBS letters (14-10-1996)“…The ORL1 (pioid eceptor‐ike) receptor is the G protein‐coupled receptor whose amino acid sequence is closest to those of opioid receptors. Residues that are…”
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ORL1, a novel member of the opioid receptor family
Published in FEBS letters (14-03-1994)“…Selective PCR amplification of human and mouse genomic DNAs with oligonucleotides encoding highly conserved regions of the δ‐opioid and somatostatin receptors…”
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A fluorimetric method for measuring lipase activity based on umbelliferyl esters
Published in Lipids (01-10-1990)“…A new fluorimetric method for measuring lipase activity is described. The fluorescent compound umbelliferone (UMB) was esterified with various unsaturated and…”
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Kinetic studies of the hydrolysis of platinum-DNA complexes by nuclease S1
Published in Chemico-biological interactions (1990)“…The antitumor agent cis-diamminedichloroplatinum(II) (cis-DDP) reacts covalently with DNA and disrupts its secondary structure. Damaged DNA, but not native…”
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Effect of the amine non‐leaving group on the structure and stability of DNA complexes with cis‐[Pt(R‐NH2)2(NO3)2]
Published in European journal of biochemistry (18-12-1991)“…The antitumor compound cis‐[Pt(NH3)2Cl2] (cisplatin), conserves two ammine ligands during gthe reaction with its cellular garget DNA. Modifications of these…”
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Platinum determination in DNA--platinum complexes by fluorescence spectrophotometry
Published in Analytical biochemistry (15-08-1978)Get more information
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Different domains of the ORL1 and κ-opioid receptors are involved in recognition of nociceptin and dynorphin A
Published in FEBS letters (08-05-1998)“…In order to gain further insight into the functional architecture of structurally related G protein-coupled receptors, the ORL1 (nociceptin) and opioid…”
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[Phe 1ψ(CH 2-NH)Gly 2]nociceptin-(1-13)-NH 2 is an agonist of the nociceptin (ORL1) receptor
Published in European journal of pharmacology (1998)“…[Phe 1 ψ(CH 2-NH)Gly 2]nociceptin-(1-13)-NH 2, a pseudopeptide analog of nociceptin, has been shown to be a selective `antagonist' of the nociceptin receptor…”
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Implication of the First and Third Extracellular Loops of the μ‐Opioid Receptor in the Formation of the Ligand Binding Site: A Study Using Chimeric μ‐Opioid/Angiotensin Receptors
Published in Journal of neurochemistry (01-05-1998)“…: Recent studies on chimeric μ/δ‐, μ/κ‐ and δ/κ‐opioid receptors have suggested that extracellular loops of the receptors were involved in the discriminatory…”
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