Search Results - "BUSTOS, Matilde"
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New insights into IL-6 family cytokines in metabolism, hepatology and gastroenterology
Published in Nature reviews. Gastroenterology & hepatology (01-11-2021)“…IL-6 family cytokines are defined by the common use of the signal-transducing receptor chain glycoprotein 130 (gp130). Increasing evidence indicates that these…”
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Physiopathology of Lifestyle Interventions in Non-Alcoholic Fatty Liver Disease (NAFLD)
Published in Nutrients (12-11-2020)“…Non-alcoholic fatty liver disease (NAFLD) is a major health problem, and its prevalence has increased in recent years. Diet and exercise interventions are the…”
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Serotonin skews human macrophage polarization through HTR2B and HTR7
Published in The Journal of immunology (1950) (01-03-2013)“…Besides its role as a neurotransmitter, serotonin (5-hydroxytryptamine, 5HT) regulates inflammation and tissue repair via a set of receptors (5HT(1-7)) whose…”
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Role of obesity-associated dysfunctional adipose tissue in cancer: A molecular nutrition approach
Published in Biochimica et biophysica acta (01-06-2011)“…Obesity is a complex disease caused by the interaction of a myriad of genetic, dietary, lifestyle and environmental factors, which favors a chronic positive…”
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Identification of IL-6 Signalling Components as Predictors of Severity and Outcome in COVID-19
Published in Frontiers in immunology (13-05-2022)“…IL-6 is one of the major mediators of the hyper-inflammatory responses with complex biological functions as it can signal different modes of action. IL-6 by…”
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Cardiotrophin-1 Is a Key Regulator of Glucose and Lipid Metabolism
Published in Cell metabolism (03-08-2011)“…Cardiotrophin-1 (CT-1) is a member of the gp130 family of cytokines. We observed that ct-1 −/− mice develop mature-onset obesity, insulin resistance, and…”
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The Gene Signature of Activated M-CSF-Primed Human Monocyte-Derived Macrophages Is IL-10-Dependent
Published in Journal of innate immunity (01-05-2022)“…During inflammatory responses, monocytes are recruited into inflamed tissues, where they become monocyte-derived macrophages and acquire pro-inflammatory and…”
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Cardiotrophin-1 stimulates lipolysis through the regulation of main adipose tissue lipases[S]
Published in Journal of lipid research (01-12-2014)“…Cardiotrophin-1 (CT-1) is a cytokine with antiobesity properties and with a role in lipid metabolism regulation and adipose tissue function. The aim of this…”
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Cardiotrophin-1 Promotes a High Survival Rate in Rabbits with Lethal Fulminant Hepatitis of Viral Origin
Published in Journal of Virology (01-12-2011)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Eicosapentaenoic acid stimulates AMP-activated protein kinase and increases visfatin secretion in cultured murine adipocytes
Published in Clinical science (1979) (14-08-2009)“…Visfatin is an adipokine highly expressed in visceral AT (adipose tissue) of humans and rodents, the production of which seems to be dysregulated in excessive…”
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Role of cardiotrophin‐1 in the regulation of metabolic circadian rhythms and adipose core clock genes in mice and characterization of 24‐h circulating CT‐1 profiles in normal‐weight and overweight/obese subjects
Published in The FASEB journal (01-04-2017)“…Cardiotrophin (CT)‐1 is a regulator of glucose and lipid homeostasis. In the present study, we analyzed whether CT‐1 also acts to peripherally regulate…”
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Eicosapentaenoic acid up-regulates apelin secretion and gene expression in 3T3-L1 adipocytes
Published in Molecular nutrition & food research (01-05-2010)“…Recent studies have shown the ability of apelin to restore glucose tolerance in obese and insulin-resistant mice. Eicosapentaenoic acid (EPA) is a…”
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The pathogen receptor liver and lymph node sinusoidal endotelial cell C‐type lectin is expressed in human Kupffer cells and regulated by PU.1
Published in Hepatology (Baltimore, Md.) (01-01-2009)“…Human LSECtin (liver and lymph node sinusoidal endothelial cell C‐type lectin, CLEC4G) is a C‐type lectin encoded within the L‐SIGN/DC‐SIGN/CD23 gene cluster…”
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Protection against liver damage by cardiotrophin-1: a hepatocyte survival factor up-regulated in the regenerating liver in rats
Published in Gastroenterology (New York, N.Y. 1943) (01-07-2003)“…Cardiotrophin-1 (CT-1) is a member of the interleukin 6 (IL-6) family of cytokines, which protect cardiac myocytes against thermal and ischemic insults. In…”
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Interplay among cardiotrophin-1, prostaglandins, and vascular endothelial growth factor in rat liver regeneration
Published in Hepatology (Baltimore, Md.) (01-03-2005)“…Prostaglandins are hepatoprotective molecules generated in liver regeneration by the rapid induction of cyclooxygenase-2 (COX-2). Cardiotrophin-1 (CT-1) and…”
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Role of cardiotrophin-1 in obesity and insulin resistance
Published in Adipocyte (01-04-2012)“…Cardiotrophin-1 (CT-1) is a member of the gp130 family of cytokines. In a recent study we examined the metabolic features of ct-1 null mice and the effects on…”
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Gp130 Signaling in NOD2-Driven Crohn’s Disease: A Key Player in Fibrosis and a Novel Target for Refractory Patients
Published in Gastroenterology (New York, N.Y. 1943) (01-09-2021)Get full text
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FRI-288-Physiological levels of cardiotrophin-1 (CT-1) contribute to fasting-induced free fatty acid mobilization
Published in Journal of hepatology (01-04-2019)Get full text
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Cardiotrophin-1: A multifaceted cytokine
Published in Cytokine & growth factor reviews (01-10-2015)“…Highlights • A detailed overview of the biological actions of cardiotrophin-1 is given. • The role of cardiotrophin-1 in metabolism is briefly reviewed. • The…”
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Cardiotrophin‐1 contributes to metabolic adaptations through the regulation of lipid metabolism and to the fasting‐induced fatty acid mobilization
Published in The FASEB journal (01-12-2020)“…It is becoming clear that several human pathologies are caused by altered metabolic adaptations. During liver development, there are physiological changes,…”
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