Search Results - "BUSQUETS, Silvia"

Cachexia and sarcopenia: mechanisms and potential targets for intervention by Argilés, Josep M, Busquets, Silvia, Stemmler, Britta, López-Soriano, Francisco J

“…Highlights • Cachexia and sarcopenia share common trends: altered protein synthesis and degradation. • Cachexia and sarcopenia are both driven by inflammation…”
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Autophagy Exacerbates Muscle Wasting in Cancer Cachexia and Impairs Mitochondrial Function by Penna, Fabio, Ballarò, Riccardo, Martinez-Cristobal, Paula, Sala, David, Sebastian, David, Busquets, Silvia, Muscaritoli, Maurizio, Argilés, Josep M., Costelli, Paola, Zorzano, Antonio

“…Cancer cachexia is a multifactorial syndrome characterized by anorexia, weight loss and muscle wasting that impairs patients' quality of life and survival. Aim…”
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Therapeutic strategies against cancer cachexia by Argilés, Josep M., López-Soriano, Francisco Javier, Stemmler, Britta, Busquets, Silvia

“…Cancer cachexia has two main components: anorexia and metabolic alterations. The main changes associated with the development of this multi-organic syndrome…”
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Complete reversal of muscle wasting in experimental cancer cachexia: Additive effects of activin type II receptor inhibition and [beta]-2 agonist by Toledo, Míriam, Busquets, Sílvia, Penna, Fabio, Zhou, Xiaolan, Marmonti, Enrica, Betancourt, Angelica, Massa, David, Lopez-Soriano, Francisco J, Han, HQ, Argiles, Josep M

“…Formoterol is a highly potent [beta]2-adrenoceptor-selective agonist, which is a muscle growth promoter in many animal species. Myostatin/activin inhibition…”
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Mitochondrial and sarcoplasmic reticulum abnormalities in cancer cachexia: Altered energetic efficiency? by Fontes-Oliveira, Cibely Cristine, Busquets, Sílvia, Toledo, Míriam, Penna, Fabio, Aylwin, Maria Paz, Sirisi, Sònia, Silva, Ana Paula, Orpí, Marcel, García, Albert, Sette, Angelica, Genovese, Maria Inês, Olivan, Mireia, López-Soriano, Francisco J., Argilés, Josep M.

“…Cachexia is a wasting condition that manifests in several types of cancer, and the main characteristic is the profound loss of muscle mass. The Yoshida AH-130…”
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Myostatin blockage using actRIIB antagonism in mice bearing the Lewis lung carcinoma results in the improvement of muscle wasting and physical performance by Busquets, Sílvia, Toledo, Míriam, Orpí, Marcel, Massa, David, Porta, Maria, Capdevila, Eva, Padilla, Núria, Frailis, Valentina, López-Soriano, Francisco J., Han, H. Q., Argilés, Josep M.

“…Background Cachexia is a multiorganic syndrome associated with cancer, characterized by body weight loss, muscle and adipose tissue wasting and inflammation…”
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Effects of the beta2 agonist formoterol on atrophy signaling, autophagy, and muscle phenotype in respiratory and limb muscles of rats with cancer-induced cachexia by Salazar-Degracia, Anna, Busquets, Sílvia, Argilés, Josep M., Bargalló-Gispert, Núria, López-Soriano, Francisco J., Barreiro, Esther

“…Muscle mass loss and wasting are characteristic features of patients with chronic conditions including cancer. Beta-adrenoceptors attenuate muscle wasting. We…”
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Combination of exercise training and erythropoietin prevents cancer-induced muscle alterations by Pin, Fabrizio, Busquets, Silvia, Toledo, Miriam, Camperi, Andrea, Lopez-Soriano, Francisco J, Costelli, Paola, Argilés, Josep M, Penna, Fabio

“…Cancer cachexia is a syndrome characterized by loss of skeletal muscle mass, inflammation, anorexia and anemia, contributing to patient fatigue and reduced…”
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Differential structural features in soleus and gastrocnemius of carnitine‐treated cancer cachectic rats by Busquets, Sílvia, Pérez‐Peiró, Maria, Salazar‐Degracia, Anna, Argilés, Josep M., Serpe, Roberto, Rojano‐Toimil, Alba, López‐Soriano, Francisco J., Barreiro, Esther

“…Muscle wasting is associated with chronic diseases and cancer. Elucidation of the biological mechanism involved in the process of muscle mass loss and cachexia…”
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Are there any benefits of exercise training in cancer cachexia? by Argilés, Josep M., Busquets, Sílvia, López-Soriano, Francisco J., Costelli, Paola, Penna, Fabio

“…Cancer cachexia is a complex syndrome characterized by inflammation, body weight loss, muscle, and adipose tissue wasting that is responsible for the death of…”
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Nonmuscle Tissues Contribution to Cancer Cachexia by Argilés, Josep M., Stemmler, Britta, López-Soriano, Francisco J., Busquets, Silvia

“…Cachexia is a syndrome associated with cancer, characterized by body weight loss, muscle and adipose tissue wasting, and inflammation, being often associated…”
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Redox balance and carbonylated proteins in limb and heart muscles of cachectic rats by Marin-Corral, Judith, Fontes, Cibely C, Pascual-Guardia, Sergi, Sanchez, Francisco, Olivan, Mireia, Argilés, Josep M, Busquets, Sílvia, López-Soriano, Francisco J, Barreiro, Esther

“…In fast- and slow-twitch limb and heart muscles of cachectic rats, redox balance and muscle structure were explored. The nature of the oxidatively modified…”
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Inhibition of xanthine oxidase reduces wasting and improves outcome in a rat model of cancer cachexia by Springer, Jochen, Tschirner, Anika, Hartman, Kai, Palus, Sandra, Wirth, Eva K., Ruis, Silvia Busquets, Möller, Nadine, von Haehling, Stephan, Argiles, Josep M., Köhrle, Josef, Adams, Volker, Anker, Stefan D., Doehner, Wolfram

“…Cachexia is a common co‐morbidity in cancer occurring in up to 80% of patients depending on the type of cancer. Uric acid (UA), the end‐product of the purine…”
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A Rat Immobilization Model Based on Cage Volume Reduction: A Physiological Model for Bed Rest? by Marmonti, Enrica, Busquets, Sílvia, Toledo, Míriam, Ricci, Marina, Beltrà, Marc, Gudiño, Victòria, Oliva, Francesc, López-Pedrosa, José M, Manzano, Manuel, Rueda, Ricardo, López-Soriano, Francisco J, Argilés, Josep M

“…Bed rest has been an established treatment in the past prescribed for critically illness or convalescing patients, in order to preserve their body metabolic…”
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A multifactorial anti‐cachectic approach for cancer cachexia in a rat model undergoing chemotherapy by Toledo, Míriam, Penna, Fabio, Oliva, Francesc, Luque, Melania, Betancourt, Angelica, Marmonti, Enrica, López‐Soriano, Francisco J., Argilés, Josep M., Busquets, Sílvia

“…Background The effectiveness of drugs aimed at counteracting cancer cachexia is generally tested in pre‐clinical rodent models, where only the tumour‐induced…”
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Effects of S‐pindolol in mouse pancreatic and lung cancer cachexia models by Springer, Jochen, Jové, Queralt, Lima Junior, Edson Alves, Ladrón, Natalia Álvarez, López‐Soriano, Francisco Javier, Busquets, Silvia, Argiles, Josep M., Marks, Daniel L.

“…Background It is known that S‐pindolol attenuates muscle loss in animal models of cancer cachexia and sarcopenia. In cancer cachexia, it also significantly…”
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Formoterol in the treatment of experimental cancer cachexia: effects on heart function by Toledo, Míriam, Springer, Jochen, Busquets, Sílvia, Tschirner, Anika, López-Soriano, Francisco J., Anker, Stefan D., Argilés, Josep M.

“…Background and aims Formoterol is a highly potent β2-adrenoceptor-selective agonist, which is a muscle growth promoter in many animal species, resulting in…”
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Anabolic deficits and divergent unfolded protein response underlie skeletal and cardiac muscle growth impairments in the Yoshida hepatoma tumor model of cancer cachexia by Belcher, Daniel J., Kim, Nina, Navarro‐Llinas, Blanca, Möller, Maria, López‐Soriano, Francisco J., Busquets, Silvia, Nader, Gustavo A.

“…Cancer cachexia manifests as whole body wasting, however, the precise mechanisms governing the alterations in skeletal muscle and cardiac anabolism have yet to…”
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Formoterol reduces muscle wasting in mice undergoing doxorubicin chemotherapy by de Lima Junior, Edson Alves, Teixeira, Alexandre Abilio de Souza, Silveira, Loreana Sanches, Jové, Queralt, Ladrón, Natalia Álvarez, Pereira, Marcelo G, López-Soriano, Francisco Javier, Argilés, Josep M, Brum, Patrícia Chakur, Busquets, Silvia, Neto, José Cesar Rosa

“…Even though doxorubicin (DOX) chemotherapy promotes intense muscle wasting, this drug is still widely used in clinical practice due to its remarkable…”
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Editorial: Biological Mechanism-Based and Patient-Centered Management of Cancer-Related Symptoms and Syndromes by Macciò, Antonio, Busquets, Silvia, Madeddu, Clelia, Argilés, Josep M

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