Search Results - "BUSH, C"

Single-cell transcriptomics of human T cells reveals tissue and activation signatures in health and disease by Szabo, Peter A., Levitin, Hanna Mendes, Miron, Michelle, Snyder, Mark E., Senda, Takashi, Yuan, Jinzhou, Cheng, Yim Ling, Bush, Erin C., Dogra, Pranay, Thapa, Puspa, Farber, Donna L., Sims, Peter A.

“…Human T cells coordinate adaptive immunity in diverse anatomic compartments through production of cytokines and effector molecules, but it is unclear how…”
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Single-Cell Genomics Reveals a Novel Cell State During Smooth Muscle Cell Phenotypic Switching and Potential Therapeutic Targets for Atherosclerosis in Mouse and Human by Pan, Huize, Xue, Chenyi, Auerbach, Benjamin J., Fan, Jiaxin, Bashore, Alexander C., Cui, Jian, Yang, Dina Y., Trignano, Sarah B., Liu, Wen, Shi, Jianting, Ihuegbu, Chinyere O., Bush, Erin C., Worley, Jeremy, Vlahos, Lukas, Laise, Pasquale, Solomon, Robert A., Connolly, Edward S., Califano, Andrea, Sims, Peter A., Zhang, Hanrui, Li, Mingyao, Reilly, Muredach P.

“…BACKGROUND:Smooth muscle cells (SMC) play significant roles in atherosclerosis via phenotypic switching, a pathological process in which SMC dedifferentiation,…”
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Single-cell transcriptome analysis of lineage diversity in high-grade glioma by Yuan, Jinzhou, Levitin, Hanna Mendes, Frattini, Veronique, Bush, Erin C, Boyett, Deborah M, Samanamud, Jorge, Ceccarelli, Michele, Dovas, Athanassios, Zanazzi, George, Canoll, Peter, Bruce, Jeffrey N, Lasorella, Anna, Iavarone, Antonio, Sims, Peter A

“…Despite extensive molecular characterization, we lack a comprehensive understanding of lineage identity, differentiation, and proliferation in high-grade…”
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PLATE-Seq for genome-wide regulatory network analysis of high-throughput screens by Bush, Erin C., Ray, Forest, Alvarez, Mariano J., Realubit, Ronald, Li, Hai, Karan, Charles, Califano, Andrea, Sims, Peter A.

“…Pharmacological and functional genomic screens play an essential role in the discovery and characterization of therapeutic targets and associated…”
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Comparative Structural and Antigenic Characterization of Genetically Distinct Flavobacterium psychrophilum O -Polysaccharides by Cisar, John O, Bush, C Allen, Wiens, Gregory D

“…Little is known about the underlying basis of serotype specificity among strains of , the agent of rainbow trout fry syndrome and bacterial cold-water disease…”
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xenoGI 3: using the DTLOR model to reconstruct the evolution of gene families in clades of microbes by Liu, Nuo, Gonzalez, Tonatiuh A, Fischer, Jacob, Hong, Chan, Johnson, Michelle, Mawhorter, Ross, Mugnatto, Fabrizia, Soh, Rachael, Somji, Shifa, Wirth, Joseph S, Libeskind-Hadas, Ran, Bush, Eliot C

“…To understand genome evolution in a group of microbes, we need to know the timing of events such as duplications, deletions and horizontal transfers. A common…”
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De novo gene signature identification from single‐cell RNA‐seq with hierarchical Poisson factorization by Levitin, Hanna Mendes, Yuan, Jinzhou, Cheng, Yim Ling, Ruiz, Francisco JR, Bush, Erin C, Bruce, Jeffrey N, Canoll, Peter, Iavarone, Antonio, Lasorella, Anna, Blei, David M, Sims, Peter A

“…Common approaches to gene signature discovery in single‐cell RNA‐sequencing (scRNA‐seq) depend upon predefined structures like clusters or pseudo‐temporal…”
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Skeletal muscle diffusion tensor‐MRI fiber tracking: rationale, data acquisition and analysis methods, applications and future directions by Damon, Bruce M., Froeling, Martijn, Buck, Amanda K. W., Oudeman, Jos, Ding, Zhaohua, Nederveen, Aart J., Bush, Emily C., Strijkers, Gustav J.

“…The mechanical functions of muscles involve the generation of force and the actuation of movement by shortening or lengthening under load. These functions are…”
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Imaging the May 2024 Extreme Aurora With Ionospheric Total Electron Content by Foster, J. C., Erickson, P. J., Nishimura, Y., Zhang, S. R., Bush, D. C., Coster, A. J., Meade, P. E., Franco‐Diaz, E.

“…The continental United States is well instrumented with facilities for mid‐latitude upper atmosphere research that operate on a continuous basis. In addition,…”
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Epilepsy and the smell of fear by Maa, E.H., Arnold, J., Bush, C.K.

“…•Menthone has been identified as the dominant constituent of seizure-scented sweat.•Canines were unable to distinguish between fear-scented and seizure-scented…”
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Neurobartonelloses: emerging from obscurity by Bush, Janice C, Robveille, Cynthia, Maggi, Ricardo G, Breitschwerdt, Edward B

“…Bartonella species are fastidious, intracellular bacteria responsible for an expanding array of human pathologies. Most are considered to be transmitted by…”
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Identification and genetic engineering of pneumococcal capsule-like polysaccharides in commensal oral streptococci by Wu, Ren, Nahm, Moon, Yang, Jinghua, Bush, C Allen, Wu, Hui

“…Capsular polysaccharides (CPS) in are pivotal for bacterial virulence and present extensive diversity. While oral streptococci show pronounced antigenicity…”
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Cold exposure induces dynamic, heterogeneous alterations in human brown adipose tissue lipid content by Coolbaugh, Crystal L., Damon, Bruce M., Bush, Emily C., Welch, E. Brian, Towse, Theodore F.

“…Brown adipose tissue undergoes a dynamic, heterogeneous response to cold exposure that can include the simultaneous synthesis, uptake, and oxidation of fatty…”
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Genome-Wide Transcriptional Response to Varying RpoS Levels in Escherichia coli K-12 by Wong, Garrett T, Bonocora, Richard P, Schep, Alicia N, Beeler, Suzannah M, Lee Fong, Anna J, Shull, Lauren M, Batachari, Lakshmi E, Dillon, Moira, Evans, Ciaran, Becker, Carla J, Bush, Eliot C, Hardin, Johanna, Wade, Joseph T, Stoebel, Daniel M

“…The alternative sigma factor RpoS is a central regulator of many stress responses in The level of functional RpoS differs depending on the stress. The effect…”
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Effects of Noise on the Behavioral and Neural Categorization of Speech by Bidelman, Gavin M, Bush, Lauren C, Boudreaux, Alex M

“…We investigated whether the categorical perception (CP) of speech might also provide a mechanism that aids its perception in noise. We varied signal-to-noise…”
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Adipose tissue fatty acid storage factors: effects of depot, sex and fat cell size by Hames, K C, Koutsari, C, Santosa, S, Bush, N C, Jensen, M D

“…Background/objectives: Patterns of postabsorptive adipose tissue fatty acid storage correlate with sex-specific body fat distribution. Some proteins and…”
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Structures of Capsular Polysaccharide Serotypes 35F and 35C of Streptococcus pneumoniae Determined by Nuclear Magnetic Resonance and Their Relation to Other Cross-Reactive Serotypes by Bush, C Allen, Cisar, John O, Yang, Jinghua

“…The structures of Streptococcus pneumoniae capsular polysaccharides (CPSs) are essential for defining the antigenic as well as genetic relationships between…”
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Viability and Desiccation Resistance of Bartonella henselae in Biological and Non-Biological Fluids: Evidence for Pathogen Environmental Stability by Bush, Janice C, Maggi, Ricardo G, Breitschwerdt, Edward B

“…Pathogen environmental stability is an often-neglected research priority for pathogens that are known to be vector-transmitted. , the etiologic agent of Cat…”
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WciG O -Acetyltransferase Functionality Differentiates Pneumococcal Serotypes 35C and 42 by Geno, K Aaron, Bush, C Allen, Wang, Mengnan, Jin, Cheng, Nahm, Moon H, Yang, Jinghua

“…expresses capsular polysaccharides (CPSs) to protect itself from opsonophagocytic killing. The genes responsible for capsules synthesized by the Wzy-dependent…”
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Chemical Structures of Streptococcus pneumoniae Capsular Polysaccharide Type 39 (CPS39), CPS47F, and CPS34 Characterized by Nuclear Magnetic Resonance Spectroscopy and Their Relation to CPS10A by Bush, C. Allen, Yang, Jinghua, Yu, Bingwu, Cisar, John O

“…Structural characterization of Streptococcus pneumoniae capsular polysaccharides (CPS) is a prerequisite for unraveling both antigenic and genetic…”
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