Search Results - "BUSBY, W. F"

Effect of methanol, ethanol, dimethyl sulfoxide, and acetonitrile on in vitro activities of cDNA-expressed human cytochromes P-450 by BUSBY, W. F, ACKERMANN, J. M, CRESPI, C. L

“…The effects of methanol, ethanol, dimethyl sulfoxide (DMSO), and acetonitrile were studied in vitro on nine individual, cDNAexpressed cytochrome P-450…”
Get full text

Bioassay-Directed Chemical Analysis of Los Angeles Airborne Particulate Matter Using a Human Cell Mutagenicity Assay by Hannigan, Michael P, Cass, Glen R, Penman, Bruce W, Crespi, Charles L, Lafleur, Arthur L, Busby, William F, Thilly, William G, Simoneit, Bernd R. T

“…The human cell mutagenicity of Los Angeles airborne fine particulate matter is examined via bioassay-directed chemical analysis. A 1993 composite fine particle…”
Get full text

Human Lymphoblast Mutagens in Urban Airborne Particles by Durant, John L, Lafleur, Arthur L, Plummer, Elaine F, Taghizadeh, Koli, Busby, William F, Thilly, William G

“…While it is known that urban airborne particles typically contain trace levels of bacterial mutagens and rodent carcinogens, little work has been done to…”
Get full text

Comparative tumorigenicity of the cyclopenta-fused polycyclic aromatic hydrocarbons aceanthrylene, dihydroaceanthrylene and acephenanthrylene in preweanling CD-1 and BLU:Ha mouse bioassays by Wang, Jia-Sheng, He, Xia, Mulder, Patrick P.J., Boere, Ben B., Cornelisse, Jan, Lugtenburg, Johan, Busby Jr, William F.

“…Cyclopenta-fused polycyclic aromatic hydrocarbons are ubiquitous environmental pollutants and potential human health biohazards. In this study, the…”
Get full text

Subinhibitory concentrations of cefpodoxime alter membrane protein expression of Actinobacillus actinomycetemcomitans and enhance its susceptibility to killing by neutrophils by BAKER, P. J, BUSBY, W. F, WILSON, M. E

“…Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon…”
Get full text

Effects of PAH isomerizations on mutagenicity of combustion products by Howard, Jack B., Longwell, John P., Marr, Joseph A., Pope, Christopher J., Busby, William F., Lafleur, Arthur L., Taghizadeh, Koli

“…Most of the mutagenicity of mixtures of polycyclic aromatic hydrocarbons (PAH) mixtures found in combustion exhaust gases is contributed by a relatively small…”
Get full text

Dose-response relationships of the tumorigenicity of cyclopenta[cd]pyrene, benzo[a]pyrene and 6-nitrochrysene in a newborn mouse lung adenoma bioassay by Busby, Jr, W F, Stevens, E K, Kellenbach, E R, Cornelisse, J, Lugtenburg, J

“…Cyclopenta[cd]pyrene (CPP) was a potent tumorigen when tested over a 5-fold dose range in the newborn mouse assay. A 20-fold increase in lung tumor…”
Get more information

Formation and persistence of DNA adducts in organs of CD-1 mice treated with a tumorigenic dose of fluoranthene by Wang, J S, Busby, Jr, W F, Wogan, G N

“…Fluoranthene (FA) is tumorigenic to the lung when injected i.p. into CD-1 mice 1, 8 and 15 days after birth (Wang, J.-S. and Busby, W.F. Jr, Carcinogenesis,…”
Get more information

Structural identification of the major DNA adduct formed by aflatoxin B1 in vitro by J M Essigmann, R G Croy, A M Nadzan, W F Busby, Jr, V N Reinhold, G Büchi, G N Wogan

“…The covalent binding of the hepatocarcinogen aflatoxin B1 by rat liver microsomes to calf thymus DNA resulted in a binding level equal to one aflatoxin residue…”
Get full text

Percutaneous Absorption and Tissue Distribution of [3H]Diacetoxyscirpenol (Anguidine) in Rats and Mice by Wang, Jia-Sheng, Busby, Jr, William F., Wogan, Gerald N.

“…Acute toxicity, absorption, excretion, and tissue distribution of topically administered diacetoxyscirpenol (DAS, anguidine) were studied in Fischer rats and…”
Get full text

Mutagenicity of the atmospheric transformation products 2-nitrofluoranthene and 2-nitrodibenzopyranone in Salmonella and human cell forward mutation assays by Busby Jr, William F, Smith, Henrietta, Crespi, Charles L, Penman, Bruce W, Lafleur, Arthur L

“…The mutagenicity of the atmospheric transformation products 2-nitrofluoranthene (2-NF) and 2-nitrodibenzopyranone (2-NDBP), as well as a related isomer…”
Get full text

Mutagenicity of cyclopenta-fused polynuclear aromatic hydrocarbons and a non-polar fraction from a fuel combustion sample in a Salmonella forward mutation assay without exogenous metabolic activation by Busby Jr, William F, Smith, Henrietta, Plummer, Elaine F, Lafleur, Arthur L, Mulder, Patrick P.J, Boere, Ben B, Cornelisse, Jan, Lugtenburg, Johan

“…A series of cyclopenta-fused polynuclear aromatic hydrocarbons (PAH) were tested for mutagenicity in a bacterial forward mutation assay based on resistance to…”
Get full text

Induction of lung and liver tumors by fluoranthene in a preweanling CD-1 mouse bioassay by Wang, J S, Busby, Jr, W F

“…Fluoranthene (FA), a major environmental pollutant, induced lung and liver tumors 6-9 months after intraperitoneal injection of 0.7, 1.75 and 3.5 mg FA into…”
Get more information

Lung tumorigenicity of benzene oxide, benzene dihydrodiols and benzene diolepoxides in the BLU:Ha newborn mouse assay by Busby, Jr, W F, Wang, J S, Stevens, E K, Padykula, R E, Aleksejczyk, R A, Berchtold, G A

“…Metabolic activation of benzene may occur by a pathway analogous to that accepted for polynuclear aromatic hydrocarbons (PAHs) involving ring epoxidation,…”
Get more information

Tumorigenicity of fluoranthene in a newborn mouse lung adenoma bioassay by Busby, Jr, W F, Goldman, M E, Newberne, P M, Wogan, G N

“…A 24 week lung adenoma bioassay using newborn mice was employed to determine the tumorigenicity of fluoranthene, a common environmental polynuclear aromatic…”
Get more information

Comparative lung tumorigenicity of parent and mononitro-polynuclear aromatic hydrocarbons in the BLU:Ha newborn mouse assay by Busby, Jr, W F, Stevens, E K, Martin, C N, Chow, F L, Garner, R C

“…A BLU:Ha newborn mouse lung adenoma bioassay was employed to compare the tumorigenicity of selected mononitroarenes and unsubstituted parent compounds 6 months…”
Get more information

Human Cell Mutagens in Los Angeles Air by Hannigan, Michael P, Cass, Glen R, Penman, Bruce W, Crespi, Charles L, Lafleur, Arthur L, Busby, William F, Thilly, William G

“…The human cell mutagenicity of particulate air pollution samples collected in southern California is measured. The human cell mutation assay used in this study…”
Get full text

Carcinogenicity in rats of the nitrosated bile acid conjugates N-nitrosoglycocholic acid and N-nitrosotaurocholic acid by BUSBY, W. F. JR, SHUKER, D. E. G, CHARNLEY, G, NEWBERNE, P. M, TANNENBAUM, S. R, WOGAN, G. N

“…Two nitrosated bile acid conjugates, N-nitrosoglycocholic acid and N-nitrosotaurocholic acid, were examined for carcinogenicity in a 2-year study with male…”
Get full text

Human cell mutagenicity of oxygenated, nitrated and unsubstituted polycyclic aromatic hydrocarbons associated with urban aerosols by Durant, John L., Busby, William F., Lafleur, Arthur L., Penman, Bruce W., Crespi, Charles L.

“…Polycyclic aromatic compounds (PAC) are ubiquitous pollutants in urban air that may pose risks to human health. In order to better assess the health risks…”
Get full text

Seasonal and Spatial Variation of the Bacterial Mutagenicity of Fine Organic Aerosol in Southern California by Hannigan, Michael P., Cass, Glen R., Lafleur, Arthur L., Busby, William F., Thilly, William G.

“…The bacterial mutagenicity of a set of 1993 urban particulate air pollution samples is examined using the Salmonella typhimurium TM677 forward mutation assay…”
Get full text