Search Results - "BURSTEIN, Haim"

Artificial miRNAs mitigate shRNA-mediated toxicity in the brain: Implications for the therapeutic development of RNAi by McBride, Jodi L, Boudreau, Ryan L, Harper, Scott Q, Staber, Patrick D, Monteys, Alex Mas, Martins, Inâs, Gilmore, Brian L, Burstein, Haim, Peluso, Richard W, Polisky, Barry, Carter, Barrie J, Davidson, Beverly L

“…Huntington's disease (HD) is a fatal, dominant neurodegenerative disease caused by a polyglutamine repeat expansion in exon 1 of the HD gene, which encodes the…”
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Secretion of a TNFR:Fc Fusion Protein following Pulmonary Administration of Pseudotyped Adeno-Associated Virus Vectors by SANDALON, Ziv, BRUCKHEIMER, Elizabeth M, LUSTIG, Kurt H, ROGERS, Linda C, PELUSO, Richard W, BURSTEIN, Haim

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Recombinant adeno-associated virus preferentially transduces human, compared to mouse, synovium: implications for arthritis therapy by Katakura, Shigeki, Jennings, Kristi, Watanabe, Shohei, Adachi, Eijiroh, Thornton, Sherry, Gao, Guang-ping, Wilson, James M., Burstein, Haim, Trapnell, Bruce, Hirsch, Raphael

“…Abstract Despite a number of published reports, including from our own laboratory, suggesting that adeno-associated virus (AAV) transduces mouse synovium, a…”
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AAV2 1-TNFR:Fc gene delivery prevents periodontal disease progression by Cirelli, J A, Park, C H, MacKool, K, Taba, M, Lustig, K H, Burstein, H, Giannobile, W V

“…Periodontal disease is a chronic inflammatory condition induced by tooth-associated microbial biofilms that induce a host immune response. Therapeutic control…”
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Long-term Suppression of Experimental Arthritis Following Intramuscular Administration of a Pseudotyped AAV2/1-TNFR:Fc Vector by Sandalon, Ziv, Bruckheimer, Elizabeth M, Lustig, Kurt H, Burstein, Haim

“…We previously reported that administration of an adeno-associated virus 2 (AAV2) vector encoding a rat tumor necrosis factor (TNF) receptor–immunoglobulin Fc…”
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578. Suppression of Inflammation Following Intramuscular Administration of Pseudotyped AAV-TNFR:Fc Vectors in a Rat Model of Arthritis by Burstein, Haim, Lustig, Kurt, Sandalon, Ziv

“…TNF-α antagonists such as anti-TNF-α monoclonal antibodies or soluble tumor necrosis factor receptor have proven to be useful therapeutics for the treatment of…”
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983. Repeat Intra-Articular Administration of AAV2 Vectors to Rat Joints by Burstein, Haim, Lustig, Kurt, Sandalon, Ziv

“…Rheumatoid arthritis is a chronic autoimmune disease characterized by synovial inflammation, leading to the destruction of cartilage and bone. Previously, we…”
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Intraarticular Gene Transfer of TNFR:Fc Suppresses Experimental Arthritis with Reduced Systemic Distribution of the Gene Product by Chan, James M.K., Villarreal, Gilda, Jin, Wen Wen, Stepan, Tony, Burstein, Haim, Wahl, Sharon M.

“…Tumor necrosis factor α (TNFα) plays a pivotal role in the pathogenesis of rheumatoid arthritis (RA). Blockage of TNFα actions by systemic administration of…”
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Persistent liver expression of murine apoA-l using vectors based on adeno-associated viral vectors serotypes 5 and 1 by Kitajima, Ken, Marchadier, Dawn H.L., Burstein, Haim, Rader, Daniel J.

“…Plasma levels of high-density lipoprotein-cholesterol (HDL-C) and apolipoprotein A-l (apoA-l) are inversely related to risk for coronary heart disease…”
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499. Improving the Stability of Ad-AAV Hybrid Vectors by Burstein, Haim, Peluso, Richard, Sandalon, Ziv, Lustig, Kurt, Stepan, Tony

“…The Ad/AAV hybrid vector is an E1 gene-deleted adenovirus containing a transgene cassette flanked on its 5' and 3' ends by AAV ITR vector sequences. After…”
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Persistent liver expression of murine apoA-1 using vectors based on adeno-associated viral vectors serotypes 5 and 1 by KITAJIMA, Ken, MARCHADIER, Dawn H. L, BURSTEIN, Haim, RADER, Daniel J

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99. Long-term Expression of Soluble TNFR:Fc Protein Following Multiple Administrations of AAV-TNFR:Fc Vector Pseudotyped with Capsids of Alternate Serotypes by Sandalon, Ziv, Lustig, Kurt, Burstein, Haim

“…Recently, we have demonstrated that local (intraarticular) or systemic (intramuscular) administration of an AAV-ratTNFR:Fc vector, encoding the rat tumor…”
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880. Suppression of Inflammation in a Rat Model of Arthritis Following Intramuscular Administration of AAV-TNFR:Fc Vector Pseudotyped with AAV Type 1 Capsid by Sandalon, Ziv, Lustig, Kurt, Burstein, Haim

“…TNF-alpha antagonists such as anti-TNF-alpha monoclonal antibodies or soluble tumor necrosis factor receptors have proven to be useful therapeutics for the…”
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414. Non-Allele Specific RNA Interference in the CAG140 Knock-In Mouse Model of Huntington's Disease by McBride, Jodi L., Harper, Scott Q., Staber, Patrick D., Martins, Ines H., Burstein, Haim, Peluso, Richard W., Polisky, Barry, Carter, Barrie J., Davidson, Beverly L.

“…We and others have demonstrated that RNA interference (RNAi) to silence human huntingtin transgenes in mouse models of Huntington's disease (HD) prevented…”
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Recombinant adeno-associated virus preferentially transduces human, compared to mouse, synovium: implications for arthritis therapy by Katakura, Shigeki, Jennings, Kristi, Watanabe, Shohei, Adachi, Eijiroh, Thornton, Sherry, Gao, Guang-ping, Wilson, James M, Burstein, Haim, Trapnell, Bruce, Hirsch, Raphael

“…Despite a number of published reports, including from our own laboratory, suggesting that adeno-associated virus (AAV) transduces mouse synovium, a careful…”
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Assembly and processing of avian retroviral gag polyproteins containing linked protease dimers by BURSTEIN, H, BIZUB, D, SKALKA, A. M

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Analysis of substrate interactions of the Rous sarcoma virus wild type and mutant proteases and human immunodeficiency virus-1 protease using a set of systematically altered peptide substrates by GRINDE, B, CAMERON, C. E, LEIS, J, WEBER, I. T, WLODAWER, A, BURSTEIN, H, SKALKA, A. M

“…In the preceding study, mutant Rous sarcoma virus (RSV) proteases are described in which three amino acids found in the human immunodeficiency virus-1 (HIV-1)…”
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Mutations that alter the activity of the Rous sarcoma virus protease by GRINDE, B, CAMERON, C. E, LEIS, J, WEBER, I. T, WLODOWER, A, BURSTEIN, H, BIZUB, D, SKALKA, A. M

“…Mutations designed by analysis of the Rous sarcoma virus (RSV) and human immunodeficiency virus (HIV)-1 protease (PR) crystal structures were introduced into…”
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Mutational analysis of the substrate binding pockets of the Rous sarcoma virus and human immunodeficiency virus-1 proteases by CAMERON, C. E, RIDKY, T. W, SHULENIN, S, LEIS, J, WEBER, I. R, COPELAND, T, WLODAWER, A, BURSTEIN, H, BIZUB-BENDER, D, SKALKA, A. M

“…Mutations, designed by analysis of the crystal structures of Rous sarcoma virus (RSV) and human immunodeficiency virus type 1 (HIV-1) protease (PR), were…”
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Processing of avian retroviral gag polyprotein precursors is blocked by a mutation at the NC-PR cleavage site by BURSTEIN, H, BIZUB, D, KOTLER, M, SCHATZ, G, VOGT, V. M, SKALKA, A. M

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