Search Results - "BURRONE, Oscar R"
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Recombinant Rotaviruses Rescued by Reverse Genetics Reveal the Role of NSP5 Hyperphosphorylation in the Assembly of Viral Factories
Published in Journal of virology (12-12-2019)“…Rotavirus (RV) replicates in round-shaped cytoplasmic viral factories, although how they assemble remains unknown. During RV infection, NSP5 undergoes…”
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2
VSV-G-Enveloped Vesicles for Traceless Delivery of CRISPR-Cas9
Published in Molecular therapy. Nucleic acids (07-09-2018)“…The method of delivery of CRISPR-Cas9 into target cells is a strong determinant of efficacy and specificity in genome editing. Even though high efficiency of…”
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3
Role of Capsid Anchor in the Morphogenesis of Zika Virus
Published in Journal of virology (15-11-2018)“…The flavivirus capsid protein (C) is separated from the downstream premembrane (PrM) protein by a hydrophobic sequence named capsid anchor (Ca). During…”
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4
DENV2 Pseudoviral Particles with Unprocessed Capsid Protein Are Assembled and Infectious
Published in Viruses (25-12-2019)“…Proteolytic processing of flavivirus polyprotein is a uniquely controlled process. To date, the sequential cleavage of the capsid anchor sequence at the…”
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5
The recruitment of TRiC chaperonin in rotavirus viroplasms correlates with virus replication
Published in mBio (10-04-2024)“…Rotavirus (RV) replication takes place in the viroplasms, cytosolic inclusions that allow the synthesis of virus genome segments and their encapsidation in the…”
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6
DNA-immunisation with dengue virus E protein domains I/II, but not domain III, enhances Zika, West Nile and Yellow Fever virus infection
Published in PloS one (25-07-2017)“…Dengue virus (DENV), the causative agent of dengue disease, is among the most important mosquito-borne pathogens worldwide. DENV is composed of four closely…”
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7
The VCP/p97 and YOD1 Proteins Have Different Substrate-dependent Activities in Endoplasmic Reticulum-associated Degradation (ERAD)
Published in The Journal of biological chemistry (20-11-2015)“…Endoplasmic reticulum-associated degradation (ERAD) is an essential quality control mechanism of the folding state of proteins in the secretory pathway that…”
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Thiazolides, a New Class of Antiviral Agents Effective against Rotavirus Infection, Target Viral Morphogenesis, Inhibiting Viroplasm Formation
Published in Journal of Virology (01-10-2013)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Rotavirus viroplasm fusion and perinuclear localization are dynamic processes requiring stabilized microtubules
Published in PloS one (23-10-2012)“…Rotavirus viroplasms are cytosolic, electron-dense inclusions corresponding to the viral machinery of replication responsible for viral template transcription,…”
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10
Engineered tobacco etch virus (TEV) protease active in the secretory pathway of mammalian cells
Published in Journal of biotechnology (20-10-2015)“…•The TEV protease targeted to the secretory pathway is inactivated by N-glycosylation.•We show an engineered TEV protease active in the secretory pathway of…”
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11
Efficient detection of proteins retro-translocated from the ER to the cytosol by in vivo biotinylation
Published in PloS one (24-08-2011)“…Retro-translocation from the ER to the cytosol of proteins within the secretory pathway takes place on misfolded molecules that are targeted for degradation by…”
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12
An Inhibitory Motif on the 5'UTR of Several Rotavirus Genome Segments Affects Protein Expression and Reverse Genetics Strategies
Published in PloS one (15-11-2016)“…Rotavirus genome consists of eleven segments of dsRNA, each encoding one single protein. Viral mRNAs contain an open reading frame (ORF) flanked by relatively…”
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13
New tags for recombinant protein detection and O-glycosylation reporters
Published in PloS one (06-05-2014)“…Monoclonal antibodies (mAbs), because of their unique specificity, are irreplaceable tools for scientific research. Precise mapping of the antigenic…”
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14
Cdc42-mediated MTOC polarization in dendritic cells controls targeted delivery of cytokines at the immune synapse
Published in The Journal of experimental medicine (22-11-2010)“…The immune synapse (IS) forms as dendritic cells (DCs) and T cells interact in lymph nodes during initiation of adaptive immunity. Factors that contribute to…”
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15
Dengue E Protein Domain III-Based DNA Immunisation Induces Strong Antibody Responses to All Four Viral Serotypes
Published in PLoS neglected tropical diseases (2015)“…Dengue virus (DENV) infection is a major emerging disease widely distributed throughout the tropical and subtropical regions of the world affecting several…”
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16
CD4 and BST-2/Tetherin Proteins Retro-translocate from Endoplasmic Reticulum to Cytosol as Partially Folded and Multimeric Molecules
Published in The Journal of biological chemistry (03-01-2014)“…CD4 and BST-2/Tetherin are cellular membrane proteins targeted to degradation by the HIV-1 protein Vpu. In both cases proteasomal degradation following…”
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Rotavirus Viroplasm Proteins Interact with the Cellular SUMOylation System: Implications for Viroplasm-Like Structure Formation
Published in Journal of Virology (01-01-2013)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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18
Immunogenicity and Efficacy of Zika Virus Envelope Domain III in DNA, Protein, and ChAdOx1 Adenoviral-Vectored Vaccines
Published in Vaccines (Basel) (16-06-2020)“…The flavivirus envelope protein domain III (EDIII) was an effective immunogen against dengue virus (DENV) and other related flaviviruses. Whether this can be…”
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Tobacco Etch Virus protease: A shortcut across biotechnologies
Published in Journal of biotechnology (10-08-2016)“…•TEV protease is the most popular endopeptidase for biotechnological applications.•The unique features of TEV protease are described.•The main in vitro and in…”
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Characterization of rotavirus NSP2/NSP5 interactions and the dynamics of viroplasm formation
Published in Journal of general virology (01-03-2004)“…1 International Centre for Genetic Engineering and Biotechnology, Padriciano 99, 34012 Trieste, Italy 2 Department of Biología Molecular y Celular, Centro…”
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