Search Results - "BURR, P"

The mitochondrial DNA genetic bottleneck: inheritance and beyond by Zhang, Haixin, Burr, Stephen P, Chinnery, Patrick F

“…mtDNA is a multicopy genome. When mutations exist, they can affect a varying proportion of the mtDNA present within every cell (heteroplasmy). Heteroplasmic…”
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Maternal IgA protects against the development of necrotizing enterocolitis in preterm infants by Gopalakrishna, Kathyayini P., Macadangdang, Benjamin R., Rogers, Matthew B., Tometich, Justin T., Firek, Brian A., Baker, Robyn, Ji, Junyi, Burr, Ansen H. P., Ma, Congrong, Good, Misty, Morowitz, Michael J., Hand, Timothy W.

“…Neonates are protected from colonizing bacteria by antibodies secreted into maternal milk. Necrotizing enterocolitis (NEC) is a disease of neonatal preterm…”
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Mitochondrial DNA Heteroplasmy and Purifying Selection in the Mammalian Female Germ Line by Burr, Stephen P., Pezet, Mikael, Chinnery, Patrick F.

“…Inherited mutations in the mitochondrial (mt)DNA are a major cause of human disease, with approximately 1 in 5000 people affected by one of the hundreds of…”
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The vacuolar-ATPase complex and assembly factors, TMEM199 and CCDC115, control HIF1α prolyl hydroxylation by regulating cellular iron levels by Miles, Anna L, Burr, Stephen P, Grice, Guinevere L, Nathan, James A

“…Hypoxia Inducible transcription Factors (HIFs) are principally regulated by the 2-oxoglutarate and Iron(II) prolyl hydroxylase (PHD) enzymes, which hydroxylate…”
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Extrinsic Defects in Crystalline MoO3: Solubility and Effect on the Electronic Structure by Lambert, D. S, Lennon, A, Burr, P. A

“…The effect of six potential contaminants (Cu, In, Ga, Se, Sn, and Zn) and five potential dopants (Ti, Mn, Sc, V, and Y) on the electronic and optical…”
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Mitochondrial Protein Lipoylation and the 2-Oxoglutarate Dehydrogenase Complex Controls HIF1α Stability in Aerobic Conditions by Burr, Stephen P., Costa, Ana S.H., Grice, Guinevere L., Timms, Richard T., Lobb, Ian T., Freisinger, Peter, Dodd, Roger B., Dougan, Gordon, Lehner, Paul J., Frezza, Christian, Nathan, James A.

“…Hypoxia-inducible transcription factors (HIFs) control adaptation to low oxygen environments by activating genes involved in metabolism, angiogenesis, and…”
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LRPPRC and SLIRP synergize to maintain sufficient and orderly mammalian mitochondrial translation by Rubalcava-Gracia, Diana, Bubb, Kristina, Levander, Fredrik, Burr, Stephen P, August, Amelie V, Chinnery, Patrick F, Koolmeister, Camilla, Larsson, Nils-Göran

“…Abstract In mammals, the leucine-rich pentatricopeptide repeat protein (LRPPRC) and the stem-loop interacting RNA-binding protein (SLIRP) form a complex in the…”
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The thermodynamics of hydride precipitation: The importance of entropy, enthalpy and disorder by Lumley, S.C., Grimes, R.W., Murphy, S.T., Burr, P.A., Chroneos, A., Chard-Tuckey, P.R., Wenman, M.R.

“…The precipitation of zirconium hydrides from Zr solid solution was investigated using first-principles lattice dynamics simulations. These included the…”
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MARCH6 and TRC8 facilitate the quality control of cytosolic and tail‐anchored proteins by Stefanovic‐Barrett, Sandra, Dickson, Anna S, Burr, Stephen P, Williamson, James C, Lobb, Ian T, van den Boomen, Dick JH, Lehner, Paul J, Nathan, James A

“…Misfolded or damaged proteins are typically targeted for destruction by proteasome‐mediated degradation, but the mammalian ubiquitin machinery involved is…”
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ABHD11 maintains 2-oxoglutarate metabolism by preserving functional lipoylation of the 2-oxoglutarate dehydrogenase complex by Bailey, Peter S. J., Ortmann, Brian M., Martinelli, Anthony W., Houghton, Jack W., Costa, Ana S. H., Burr, Stephen P., Antrobus, Robin, Frezza, Christian, Nathan, James A.

“…2-oxoglutarate (2-OG or α-ketoglutarate) relates mitochondrial metabolism to cell function by modulating the activity of 2-OG dependent dioxygenases involved…”
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Cell lineage-specific mitochondrial resilience during mammalian organogenesis by Burr, Stephen P., Klimm, Florian, Glynos, Angelos, Prater, Malwina, Sendon, Pamella, Nash, Pavel, Powell, Christopher A., Simard, Marie-Lune, Bonekamp, Nina A., Charl, Julia, Diaz, Hector, Bozhilova, Lyuba V., Nie, Yu, Zhang, Haixin, Frison, Michele, Falkenberg, Maria, Jones, Nick, Minczuk, Michal, Stewart, James B., Chinnery, Patrick F.

“…Mitochondrial activity differs markedly between organs, but it is not known how and when this arises. Here we show that cell lineage-specific expression…”
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Formation of intrinsic and silicon defects in MoO3 under varied oxygen partial pressure and temperature conditions: an ab initio DFT investigation by Lambert, D. S, Murphy, S. T, Lennon, A, Burr, P. A

“…Molybdenum trioxide (MoO 3 ) is a promising material for energy conversion applications, including recent uses as a hole selective contact in silicon…”
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The speciation of niobium in the oxide layer of an irradiated Low-Tin ZIRLO nuclear material by Hawes, J., Warnicke, P., Burr, P., Ferreira Sanchez, D., Grolimund, D., Partezana, J., Chiu, Y.-L., Abolhassani, S.

“…•Zirconium based material irradiated in a nuclear reactor.•XANES providing percentages of Nb0, Nb2+, Nb3+, Nb4+ and Nb5+.•Adding verification to current XANES…”
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Hydrogen accommodation in Zr second phase particles: Implications for H pick-up and hydriding of Zircaloy-2 and Zircaloy-4 by Burr, P.A., Murphy, S.T., Lumley, S.C., Wenman, M.R., Grimes, R.W.

“…Ab-initio computer simulations have been used to predict the energies associated with the accommodation of H atoms at interstitial sites in α, β-Zr and Zr–M…”
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The stability of alloying additions in Zirconium by Lumley, S.C., Murphy, S.T., Burr, P.A., Grimes, R.W., Chard-Tuckey, P.R., Wenman, M.R.

“…The interactions of Cr, Fe, Nb, Ni, Sn, V and Y with Zr are simulated using density functional theory. Thermodynamic stabilities of various different Zr based…”
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Hydrogen solubility in zirconium intermetallic second phase particles by Burr, P.A., Murphy, S.T., Lumley, S.C., Wenman, M.R., Grimes, R.W.

“…The enthalpies of solution of H in Zr binary intermetallic compounds formed with Cu, Cr, Fe, Mo, Ni, Nb, Sn and V were calculated by means of density…”
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Solubility and vacancy-mediated inter-diffusion in the Zr-Nb-Cr system by Tuli, Vidur, Claisse, Antoine, Messina, Luca, Burr, P.A.

“…To better understand the microstructural evolution of Cr-coated Zr alloy cladding, we investigate, using density functional theory calculations, the…”
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Rural water asset management practices in Ghana: the gaps and needs by Kumasi, T. C., Agbemor, B. D., Burr, P.

“…This study evaluates primary and secondary data from two districts to assess the status of asset management practices, and to examine requirements for improved…”
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Crystal structure, thermodynamics, magnetics and disorder properties of Be–Fe–Al intermetallics by Burr, P.A., Middleburgh, S.C., Grimes, R.W.

“…The elastic and magnetic properties, thermodynamical stability, deviation from stoichiometry and order/disorder transformations of phases that are relevant to…”
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Modeling and simulation of severe slugging in air–water pipeline–riser systems by Baliño, J.L., Burr, K.P., Nemoto, R.H.

“…A mathematical model, numerical simulations and stability and flow regime maps corresponding to severe slugging in pipeline–riser systems, are presented. In…”
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