Search Results - "BURNSTOCK, GEOFFREY"

Purinergic Signaling in the Cardiovascular System by Burnstock, Geoffrey

“…There is nervous control of the heart by ATP as a cotransmitter in sympathetic, parasympathetic, and sensory-motor nerves, as well as in intracardiac neurons…”
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Purinergic Signalling: Therapeutic Developments by Burnstock, Geoffrey

“…Purinergic signalling, i.e., the role of nucleotides as extracellular signalling molecules, was proposed in 1972. However, this concept was not well accepted…”
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Physiology and Pathophysiology of Purinergic Neurotransmission by Burnstock, Geoffrey

“…Autonomic Neuroscience Centre, Royal Free and University College Medical School, London, United Kingdom This review is focused on purinergic neurotransmission,…”
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Purinergic Signalling and Neurological Diseases: An Update by Burnstock, Geoffrey

“…Purinergic signalling, i.e. ATP as an extracellular signalling molecule and cotransmitter in both peripheral and central neurons, is involved in the physiology…”
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Purinergic signaling and blood vessels in health and disease by Burnstock, Geoffrey, Ralevic, Vera

“…Purinergic signaling plays important roles in control of vascular tone and remodeling. There is dual control of vascular tone by ATP released as a…”
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Pathophysiology and Therapeutic Potential of Purinergic Signaling by Burnstock, Geoffrey

“…The concept of a purinergic signaling system, using purine nucleotides and nucleosides as extracellular messengers, was first proposed over 30 years ago. After…”
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Autonomic Neurotransmission : 60 Years Since Sir Henry Dale by BURNSTOCK, Geoffrey

“…In the early twentieth century, Sir Henry Dale and others described brilliant studies of autonomic neurotransmission utilizing acetylcholine and noradrenaline…”
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Purinergic cotransmission by Burnstock, Geoffrey

“…Adenosine 5′-triphosphate (ATP) is a cotransmitter with classical transmitters in most nerves in the peripheral and central nervous systems, although the…”
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Purinergic receptors and pain by Burnstock, Geoffrey

“…There is a brief summary of the early background literature about purinergic signalling and its involvement in pain, of ATP storage, release and ectoenzymatic…”
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Purinergic Signalling and Endothelium by Burnstock, Geoffrey

“…Purinergic signalling is involved in the control of vascular tone and remodelling. Endothelial cells release purines and pyrimidines in response to changes in…”
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Control of vascular tone by purines and pyrimidines by Burnstock, Geoffrey

“…In this Commentary, the roles of uridine adenosine tetraphosphate as an endothelium‐derived contracting or relaxing factor described in the paper by Tölle et…”
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Historical review: ATP as a neurotransmitter by Burnstock, Geoffrey

“…Purinergic signalling is now recognized to be involved in a wide range of activities of the nervous system, including neuroprotection, central control of…”
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Purinergic Signalling: Pathophysiology and Therapeutic Potential by Burnstock, Geoffrey

“…The article begins with a review of the main conceptual steps involved in the development of our understanding of purinergic signalling, including…”
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Unresolved issues and controversies in purinergic signalling by Burnstock, Geoffrey

“…Some areas of current interest in the rapidly expanding purinergic signalling field that are controversial or are unresolved are highlighted in this review…”
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Purinergic Mechanosensory Transduction and Visceral Pain by Burnstock, Geoffrey

“…In this review, evidence is presented to support the hypothesis that mechanosensory transduction occurs in tubes and sacs and can initiate visceral pain…”
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Purinergic Signaling and Vascular Cell Proliferation and Death by Burnstock, Geoffrey

“…ABSTRACT—Evidence for the role of purinergic signaling (via P1 and P2Y receptors) in the proliferation of vascular smooth muscle and endothelial cells is…”
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Purinergic signalling in neuroregeneration by Burnstock, Geoffrey

“…Purinergic signalling,adenosine 5′-triphosphate（ATP）as an extracellular signalling molecule,was proposed in 1972（Burnstock,1972）.However,it was not generally…”
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Microglia: Proliferation and activation driven by the P2X7 receptor by Monif, Mastura, Burnstock, Geoffrey, Williams, David A.

“…Microglial activation is associated with the pathogenesis and progression of conditions such as Alzheimer's disease (AD), Parkinsons’ disease, prion disease,…”
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Introduction: P2 receptors by Burnstock, Geoffrey

“…The current status of ligand gated ion channel P2X and G protein-coupled P2Y receptor subtypes is described. This is followed by a summary of what is known of…”
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Introduction and perspective, historical note by Burnstock, Geoffrey

“…P2 nucleotide receptors were proposed to consist of two subfamilies based on pharmacology in 1985, named P2X and P2Y receptors. Later, this was confirmed…”
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