Search Results - "BURNS, NIGEL R."

Analysis of TYA Protein Regions Necessary for Formation of the Ty1 Virus-like Particle Structure by Brookman, Jayne L., Stott, Andrew J., Cheeseman, Philip J., Adamson, Catherine S., Holmes, David, Cole, Julie, Burns, Nigel R.

“…The yeast retrotransposon, Ty1, produces a macromolecular structure known as a virus-like particle (VLP) as an essential part of its replication cycle. The Ty1…”
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Induction of HIV-specific cytotoxic T lymphocytes in vivo with hybrid HIV-1 V3:Ty-virus-like particles by Layton, GT, Harris, SJ, Gearing, AJ, Hill-Perkins, M, Cole, JS, Griffiths, JC, Burns, NR, Kingsman, AJ, Adams, SE

“…In general, it has proven difficult to induce CTL responses using simple proteins or peptides without resorting to specialized adjuvants. In this study we show…”
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Hybrid human immunodeficiency virus Gag particles as an antigen carrier system: induction of cytotoxic T-cell and humoral responses by a Gag:V3 fusion by GRIFFITHS, J. C, HARRIS, S. J, LAYTON, G. T, BERRIE, E. L, FRENCH, T. J, BURNS, N. R, ADAMS, S. E, KINGSMAN, A. J

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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An Immunological Analysis of Ty1 Virus-like Particle Structure by Brookman, Jayne L., Stott, Andrew J., Cheeseman, Philip J., Burns, Nigel R., Adams, Sally E., Kingsman, Alan J., Gull, K.

“…We present an immunological characterization of the Ty1 virus-like particle (VLP). A panel of monoclonal and polyclonal antibodies were raised against the TYA…”
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Cryo-electron microscopy structure of yeast Ty retrotransposon virus-like particles by Palmer, K.J. (Birkbeck College, London.), Tichelaar, W, Myers, N, Burns, N.R, Butcher, S.J, Kingsman, A.J, Fuller, S.D, Saibil, H.R

“…The virus-like particles (VLPs) produced by the yeast retrotransposon Ty1 are functionally related to retroviral cores. These particles are unusual in that…”
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Yeast retrotransposon particles as antigen delivery systems by Kingsman, A J, Burns, N R, Layton, G T, Adams, S E

“…The development of technologies to produce recombinant proteins for use in the pharmaceutical industry has made substantial advances, in particular in the area…”
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Identification of Immunodominant Regions and Linear B Cell Epitopes of the gE Envelope Protein of Varicella-Zoster Virus by FOWLER, WENDY J., GARCIA-VALCARCEL, MERCEDES, HILL-PERKINS, MICHELE S., MURPHY, GARY, HARPER, DAVID R., JEFFRIES, DONALD J., BURNS, NIGEL R., ADAMS, SALLY E., KINGSMAN, ALAN J., LAYTON, GUY T.

“…The envelope proteins of varicella-zoster virus (VZV) are highly immunogenic and one of the most abundant is glycoprotein E (gE). However, its immunodominant…”
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Symmetry, flexibility and permeability in the structure of yeast retrotransposon virus-like particles by Burns, N.R, Saibil, H.R, White, N.S, Pardon, J.F, Timmins, P.A, Richardson, S.M.H, Richards, B.M, Adams, S.E, Kingsman, S.M, Kingsman, A.J

“…The virus-like particles (VLPs) of the yeast retrotransposon Ty are genetically, structurally and functionally analogous to retroviral nucleocapsids or cores…”
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Hybrid Ty virus-like particles by Adams, S E, Burns, N R, Layton, G T, Kingsman, A J

“…Vaccines need to activate antigen presenting cells, overcome genetic restriction in T-cell responses and elicit both T and B memory cells. In order to produce…”
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A novel method for the purification of HIV-1 p24 protein from hybrid Ty virus-like particles (Ty-VLPs) by Gilmour, J E, Senior, J M, Burns, N R, Esnouf, M P, Gull, K, Kingsman, S M, Kingsman, A J, Adams, S E

“…The self-assembly properties of a protein encoded by the yeast retrotransposon Ty can be exploited to produce large amounts of recombinant, particulate fusion…”
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Production and purification of hybrid ty-VLPs by Burns, N.R. (British Bio-Technology Ltd., Oxford, UK.), Gilmour, J.E.M, Kingsman, S.M, Kingsman, A.J, Adams, S.E

“…This article describes how pure Ty-VLPs (virus-like particles) can be prepared from hybrid Ty-VLPs. Many different hybrid Ty-VLPs have been produced and may be…”
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Performance characteristics of a novel immunoassay based on hybrid Ty virus-like particles (Ty-VLPs): rapid differentiation between HIV-1 and HIV-2 infection by Gilmour, J E, Read, S J, Eglin, R, Ryan, C, Burns, N R, Graff, N, Stenner, N, Kingsman, S M, Kingsman, A J, Adams, S E

“…Recombinant antigens containing all or parts of the HIV-1 proteins p24, Nef and gp41 and HIV-2 gp36 have been purified and used to develop a rapid immunoassay…”
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