Search Results - "BURNETT, J. C"
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Changes in renal function during hospitalization and soon after discharge in patients admitted for worsening heart failure in the placebo group of the EVEREST trial
Published in European heart journal (01-10-2011)“…Aim To provide an in-depth clinical characterization and analysis of outcomes of the patients hospitalized for heart failure (HF) who subsequently develop…”
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PTH: Potential role in management of heart failure
Published in Clinica chimica acta (10-06-2014)“…Biomarkers play an important role for the diagnosis and prognosis of heart failure (HF), a disease with high morbidity and mortality as well as a huge impact…”
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Insulin/glucose induces natriuretic peptide clearance receptor in human adipocytes: a metabolic link with the cardiac natriuretic pathway
Published in American journal of physiology. Regulatory, integrative and comparative physiology (01-07-2016)“…Cardiac natriuretic peptides (NP) are involved in cardiorenal regulation and in lipolysis. The NP activity is largely dependent on the ratio between the…”
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Low-dose nesiritide in human anterior myocardial infarction suppresses aldosterone and preserves ventricular function and structure: a proof of concept study
Published in Heart (British Cardiac Society) (01-08-2009)“…B-type natriuretic peptide (BNP, nesiritide) has anti-fibrotic, anti-hypertrophic, anti-inflammatory, vasodilating, lusitropic and aldosterone-inhibiting…”
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Effects of tolvaptan on dyspnoea relief from the EVEREST trials
Published in European heart journal (01-09-2009)“…Aims To describe the effects of tolvaptan therapy on dyspnoea relief based on timing of delivery, influence of concomitant therapies, and baseline patient and…”
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Natriuretic peptide levels in Atrial fibrillation : A prospective hormonal and doppler-echocardiographic study
Published in Journal of the American College of Cardiology (01-04-2000)“…The objective was to determine the independent association between atrial fibrillation (A-Fib) and activation of natriuretic peptides. The association of A-Fib…”
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Long-term L-arginine supplementation improves small-vessel coronary endothelial function in humans
Published in Circulation (New York, N.Y.) (02-06-1998)“…Coronary endothelial dysfunction is characterized by an imbalance between endothelium-derived vasodilating and vasoconstricting factors and coronary…”
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Pharmacophore-guided lead optimization: The rational design of a non-zinc coordinating, sub-micromolar inhibitor of the botulinum neurotoxin serotype a metalloprotease
Published in Bioorganic & medicinal chemistry letters (01-10-2009)“…The 3-zone pharmacophore for botulinum neurotoxin serotype A metalloprotease inhibition guided the design of a potent regioisomeric pair possessing a K i = 600…”
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Superiority of Brain Natriuretic Peptide as a Hormonal Marker of Ventricular Systolic and Diastolic Dysfunction and Ventricular Hypertrophy
Published in Hypertension (Dallas, Tex. 1979) (01-12-1996)“…Atrial and brain natriuretic peptides (ANP and BNP) are produced by the heart, and their plasma concentrations are increased in human chronic congestive heart…”
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Tumor Necrosis Factor Downregulates an Endothelial Nitric Oxide Synthase mRNA by Shortening Its Half-life
Published in Circulation research (01-07-1993)“…Nitric oxide (NO), which accounts for the biological properties of endothelium-derived relaxing factor, is generated by NO synthase (NOS). The vascular…”
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Endothelin in human congestive heart failure
Published in Circulation (New York, N.Y.) (01-04-1994)“…Although recent investigations report the elevation of plasma endothelin (ET) in congestive heart failure (CHF), it remains unclear if this elevation is that…”
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Clinical course and predictive value of congestion during hospitalization in patients admitted for worsening signs and symptoms of heart failure with reduced ejection fraction: findings from the EVEREST trial
Published in European heart journal (01-03-2013)“…Signs and symptoms of congestion are the most common cause for hospitalization for heart failure (HHF). The clinical course and prognostic value of congestion…”
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Renal localization and actions of adrenomedullin: a natriuretic peptide
Published in The American journal of physiology (01-04-1995)“…Adrenomedullin (ADM) is a newly described 52-amino acid peptide originally isolated from extracts of human pheochromocytoma and, more recently, detected in…”
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Evaluation of brain natriuretic peptide as marker of left ventricular dysfunction and hypertrophy in the population
Published in Journal of hypertension (01-08-2000)“…OBJECTIVETo evaluate brain natriuretic peptide (BNP) as marker of left ventricular (LV) dysfunction and hypertrophy in a population-based sample of 610…”
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Elevation of circulating and ventricular adrenomedullin in human congestive heart failure
Published in Circulation (New York, N.Y.) (01-08-1995)“…Adrenomedullin (ADM) is a newly discovered vasodilating and natriuretic peptide that may play an important role in cardiorenal regulation. Although ADM was…”
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Endothelin in coronary endothelial dysfunction and early atherosclerosis in humans
Published in Circulation (New York, N.Y.) (01-11-1995)“…The endothelium modulates vascular tone through release of vasodilating substances, such as endothelium-derived relaxing factors, and vasoconstricting…”
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Natriuretic peptide system in human heart failure
Published in Circulation (New York, N.Y.) (01-09-1993)“…Atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP), and C-type natriuretic peptide (CNP) are a family of structurally related peptides that…”
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Augmentation of the cardiac natriuretic peptides by beta-receptor antagonism: evidence from a population-based study
Published in Journal of the American College of Cardiology (01-12-1998)“…Objectives. The present retrospective analysis of data derived from a population-based study examined the relationship between intake of beta-receptor…”
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Circulating and Tissue Endothelin Immunoreactivity in Advanced Atherosclerosis
Published in The New England journal of medicine (03-10-1991)“…ATHEROSCLEROSIS may be initiated by endothelial injury, which then leads to the proliferation of intimal smooth-muscle cells. 1 The atherogenic smooth-muscle…”
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Vasopeptidase inhibitors: A new therapeutic concept in cardiovascular disease?
Published in Circulation (New York, N.Y.) (09-10-2001)“…The cardiovascular system is regulated by hemodynamic and neurohumoral mechanisms. These regulatory systems play a key role in modulating cardiac function,…”
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