Search Results - "BURKHART, Richard A"

Cross-Species Single-Cell Analysis of Pancreatic Ductal Adenocarcinoma Reveals Antigen-Presenting Cancer-Associated Fibroblasts by Elyada, Ela, Bolisetty, Mohan, Laise, Pasquale, Flynn, William F, Courtois, Elise T, Burkhart, Richard A, Teinor, Jonathan A, Belleau, Pascal, Biffi, Giulia, Lucito, Matthew S, Sivajothi, Santhosh, Armstrong, Todd D, Engle, Dannielle D, Yu, Kenneth H, Hao, Yuan, Wolfgang, Christopher L, Park, Youngkyu, Preall, Jonathan, Jaffee, Elizabeth M, Califano, Andrea, Robson, Paul, Tuveson, David A

“…Cancer-associated fibroblasts (CAF) are major players in the progression and drug resistance of pancreatic ductal adenocarcinoma (PDAC). CAFs constitute a…”
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Survival in Locally Advanced Pancreatic Cancer After Neoadjuvant Therapy and Surgical Resection by Gemenetzis, Georgios, Groot, Vincent P, Blair, Alex B, Laheru, Daniel A, Zheng, Lei, Narang, Amol K, Fishman, Elliot K, Hruban, Ralph H, Yu, Jun, Burkhart, Richard A, Cameron, John L, Weiss, Matthew J, Wolfgang, Christopher L, He, Jin

“…OBJECTIVE:The aim of the study was to identify the survival of patients with locally advanced pancreatic cancer (LAPC) and assess the effect of surgical…”
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Intraductal Transplantation Models of Human Pancreatic Ductal Adenocarcinoma Reveal Progressive Transition of Molecular Subtypes by Miyabayashi, Koji, Baker, Lindsey A, Deschênes, Astrid, Traub, Benno, Caligiuri, Giuseppina, Plenker, Dennis, Alagesan, Brinda, Belleau, Pascal, Li, Siran, Kendall, Jude, Jang, Gun Ho, Kawaguchi, Risa Karakida, Somerville, Tim D D, Tiriac, Hervé, Hwang, Chang-Il, Burkhart, Richard A, Roberts, Nicholas J, Wood, Laura D, Hruban, Ralph H, Gillis, Jesse, Krasnitz, Alexander, Vakoc, Christopher R, Wigler, Michael, Notta, Faiyaz, Gallinger, Steven, Park, Youngkyu, Tuveson, David A

“…Pancreatic ductal adenocarcinoma (PDAC) is the most lethal common malignancy, with little improvement in patient outcomes over the past decades. Recently,…”
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Main Duct Dilatation Is the Best Predictor of High-grade Dysplasia or Invasion in Intraductal Papillary Mucinous Neoplasms of the Pancreas by Del Chiaro, Marco, Beckman, Ross, Ateeb, Zeeshan, Orsini, Nicola, Rezaee, Neda, Manos, Lindsey, Valente, Roberto, Yuan, Chunhui, Ding, Ding, Margonis, Georgios A., Yin, Lingdi, Cameron, John L., Makary, Martin A., Burkhart, Richard A., Weiss, Matthew J., He, Jin, Arnelo, Urban, Yu, Jun, Wolfgang, Christopher L.

“…OBJECTIVE:The purpose of this study is to determine preoperative factors that are predictive of malignancy in patients undergoing pancreatic resection for…”
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Perioperative Outcomes of Robotic Pancreaticoduodenectomy: a Propensity-Matched Analysis to Open and Laparoscopic Pancreaticoduodenectomy by van Oosten, A. Floortje, Ding, Ding, Habib, Joseph R., Irfan, Ahmer, Schmocker, Ryan K., Sereni, Elisabetta, Kinny-Köster, Benedict, Wright, Michael, Groot, Vincent P., Molenaar, I. Quintus, Cameron, John L., Makary, Martin, Burkhart, Richard A., Burns, William R., Wolfgang, Christopher L., He, Jin

“…Introduction Robotic pancreaticoduodenectomy is slowly gaining acceptance within pancreatic surgery. Advantages have been demonstrated for robotic surgery in…”
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Implications of the Pattern of Disease Recurrence on Survival Following Pancreatectomy for Pancreatic Ductal Adenocarcinoma by Groot, Vincent P., Gemenetzis, Georgios, Blair, Alex B., Ding, Ding, Javed, Ammar A., Burkhart, Richard A., Yu, Jun, Borel Rinkes, Inne H., Molenaar, I. Quintus, Cameron, John L., Fishman, Elliot K., Hruban, Ralph H., Weiss, Matthew J., Wolfgang, Christopher L., He, Jin

“…Background After radical resection of pancreatic ductal adenocarcinoma (PDAC), approximately 80% of patients will develop disease recurrence. It remains…”
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Grit: A marker of residents at risk for attrition? by Burkhart, Richard A., MD, Tholey, Renee M., MD, Guinto, Donna, Yeo, Charles J., MD, Chojnacki, Karen A., MD

“…Background Attrition from general surgery residency remains constant at approximately 20% despite nearly a decade of work-hour reform and studies aiming to…”
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Recurrence after neoadjuvant therapy and resection of borderline resectable and locally advanced pancreatic cancer by Groot, Vincent P., Blair, Alex B., Gemenetzis, Georgios, Ding, Ding, Burkhart, Richard A., Yu, Jun, Borel Rinkes, Inne H.M., Molenaar, I. Quintus, Cameron, John L., Weiss, Matthew J., Wolfgang, Christopher L., He, Jin

“…The incidence, timing, and implications of recurrence in patients who underwent neoadjuvant treatment and surgical resection of borderline resectable (BRPC) or…”
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Recurrence in Patients Achieving Pathological Complete Response After Neoadjuvant Treatment for Advanced Pancreatic Cancer by Blair, Alex B., Yin, Ling-Di, Pu, Ning, Yu, Jun, Groot, Vincent P., Rozich, Noah S., Javed, Ammar A., Zheng, Lei, Cameron, John L., Burkhart, Richard A., Weiss, Matthew J., Wolfgang, Christopher L., He, Jin

“…OBJECTIVE:The aim of this study was to characterize the patterns and treatment of disease recurrence in patients achieving a pathological complete response…”
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Preoperative risk factors for conversion and learning curve of minimally invasive distal pancreatectomy by Hua, Yongfei, Javed, Ammar A., Burkhart, Richard A., Makary, Martin A., Weiss, Matthew J., Wolfgang, Christopher L., He, Jin

“…Although laparoscopic distal pancreatectomy is considered a standard approach, 10% to 40% of these are converted. The preoperative risk factors for conversion…”
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Personalized therapy in hepatocellular carcinoma: Molecular markers of prognosis and therapeutic response by Burkhart, Richard A, Ronnekleiv-Kelly, Sean M, Pawlik, Timothy M

“…Abstract Hepatocellular carcinoma (HCC) represents a growing worldwide health crisis with rising incidence, limited effective therapies and persistently poor…”
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HuR Posttranscriptionally Regulates WEE1: Implications for the DNA Damage Response in Pancreatic Cancer Cells by LAI, Shruti, BURKHART, Richard A, SAWICKI, Janet A, WINTER, Jordan M, RIGOUTSOS, Isidore, YEN, Timothy J, BRODY, Jonathan R, BEEHARRY, Neil, BHATTACHARJEE, Vikram, LONDIN, Eric R, COZZITORTO, Joseph A, ROMEO, Carmella, JIMBO, Masaya, NORRIS, Zoë A, YEO, Charles J

“…HuR (ELAV1), an RNA-binding protein abundant in cancer cells, primarily resides in the nucleus, but under specific stress (e.g., gemcitabine), HuR translocates…”
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Incidence and Severity of Pancreatogenic Diabetes After Pancreatic Resection by Burkhart, Richard A., Gerber, Susan M., Tholey, Renee M., Lamb, Kathleen M., Somasundaram, Anitha, McIntyre, Caitlin A., Fradkin, Eliza C., Ashok, Annie P., Felte, Robert F., Mehta, Jaya M., Rosato, Ernest L., Lavu, Harish, Jabbour, Serge A., Yeo, Charles J., Winter, Jordan M.

“…Background While many patients experience prolonged survival after pancreatic resection for benign or malignant disease, the long-term risk of pancreatogenic…”
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Inhibition of focal adhesion kinase enhances antitumor response of radiation therapy in pancreatic cancer through CD8+ T cells by Osipov, Arsen, Blair, Alex B, Liberto, Juliane, Wang, Jianxin, Li, Keyu, Herbst, Brian, Xu, Yao, Li, Shiqi, Niu, Nan, Rashid, Rufiaat, Ding, Ding, Liu, Yanan, Wang, Zaiqi, Wolfgang, Christopher L, Burkhart, Richard A, Laheru, Daniel, Zheng, Lei

“…Pancreatic ductal adenocarcinoma (PDAC) is a deadly malignancy, due in large part to its resistance to conventional therapies, including radiotherapy (RT)…”
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In vivo CRISPR screening identifies geranylgeranyl diphosphate as a pancreatic cancer tumor growth dependency by Kubota, Casie S., Myers, Stephanie L., Seppälä, Toni T., Burkhart, Richard A., Espenshade, Peter J.

“…Cancer cells must maintain lipid supplies for their proliferation and do so by upregulating lipogenic gene programs. The sterol regulatory element-binding…”
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Isolated pulmonary recurrence after resection of pancreatic cancer: the effect of patient factors and treatment modalities on survival by Groot, Vincent P., Blair, Alex B., Gemenetzis, Georgios, Ding, Ding, Burkhart, Richard A., van Oosten, A. Floortje, Molenaar, I. Quintus, Cameron, John L., Weiss, Matthew J., Yang, Stephen C., Wolfgang, Christopher L., He, Jin

“…The literature suggests favorable survival for patients with isolated pulmonary recurrence after resection of pancreatic ductal adenocarcinoma (PDAC) as…”
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Reducing colorectal surgical site infections: a novel, resident-driven, quality initiative by Hewitt, Daniel Brock, M.D., M.P.H, Tannouri, Sami S., M.D, Burkhart, Richard A., M.D, Altmark, Randi, R.N, Goldstein, Scott D., M.D, Isenberg, Gerald A., M.D, Phillips, Benjamin R., M.D, Yeo, Charles J., M.D, Cowan, Scott W., M.D

“…Abstract Background Surgical site infections (SSIs) cause significant patient morbidity and increase costs. This work prospectively examines our institutional…”
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Management of Type 9 Hepatic Arterial Anatomy at the time of Pancreaticoduodenectomy: Considerations for Preservation and Reconstruction of a Completely Replaced Common Hepatic Artery by Hicks, Caitlin W., Burkhart, Richard. A., Weiss, Matthew J., Wolfgang, Christopher L., Cameron, Andrew M., Pawlik, Timothy M.

“…Recognition and management of aberrant hepatic arterial anatomy for patients undergoing pancreaticoduodenectomy (PD) are critical to ensure safe completion of…”
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Role of exosomes in treatment of hepatocellular carcinoma by Moris, Demetrios, MD, MSc, PhD, MACS, Beal, Eliza W., MD, Chakedis, Jeffery, MD, Burkhart, Richard A., MD, Schmidt, Carl, MD, Dillhoff, Mary, MD, Zhang, Xufeng, MD, Theocharis, Stamatios, MD, PhD, Pawlik, Timothy M., MD, MPH, PhD, FACS, FRACS (Hon.)

“…Abstract Exosomes are nanovesicles that may play a role in intercellular communication by acting as carriers of functional contents such as proteins, lipids,…”
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Long-term survival after resection of sarcomatoid carcinoma of the pancreas: an updated experience by Blair, Alex B., MD, Burkhart, Richard A., MD, Griffin, James, MD, Miller, James A., MD, Weiss, Matthew J., MD, Cameron, John L., MD, Wolfgang, Christopher L., MD, PhD, He, Jin, MD, PhD

“…Abstract Background Sarcomatoid carcinoma of the pancreas (SCP) is a rare histologic subtype of undifferentiated pancreatic carcinoma. Historically, this has…”
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