Search Results - "BURKHARDT, Ute"

Haematological malignancies: at the forefront of immunotherapeutic innovation by Bachireddy, Pavan, Burkhardt, Ute E., Rajasagi, Mohini, Wu, Catherine J.

“…Key Points The impressive potency of novel cancer immunotherapies has refocused attention on this class of agents for both solid and haematological cancers,…”
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Serving up whatever you wish: CRISPR-base editing generates novel cancer-restricted antigens for immunotherapy by Burkhardt, Ute E., Fritsch, Edward F.

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Personal Neoantigen Cancer Vaccines: A Road Not Fully Paved by Fritsch, Edward F, Burkhardt, Ute E, Hacohen, Nir, Wu, Catherine J

“…Personal neoantigen-based cancer vaccines are designed to target antigens arising from tumor-specific mutations within individual cancers and present a…”
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A cloning and expression system to probe T-cell receptor specificity and assess functional avidity to neoantigens by Hu, Zhuting, Anandappa, Annabelle J., Sun, Jing, Kim, Jintaek, Leet, Donna E., Bozym, David J., Chen, Christina, Williams, Louise, Shukla, Sachet A., Zhang, Wandi, Tabbaa, Diana, Steelman, Scott, Olive, Oriol, Livak, Kenneth J., Kishi, Hiroyuki, Muraguchi, Atsushi, Guleria, Indira, Stevens, Jonathan, Lane, William J., Burkhardt, Ute E., Fritsch, Edward F., Neuberg, Donna, Ott, Patrick A., Keskin, Derin B., Hacohen, Nir, Wu, Catherine J.

“…Recent studies have highlighted the promise of targeting tumor neoantigens to generate potent antitumor immune responses and provide strong motivation for…”
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Autologous CLL cell vaccination early after transplant induces leukemia-specific T cells by Burkhardt, Ute E, Hainz, Ursula, Stevenson, Kristen, Goldstein, Natalie R, Pasek, Mildred, Naito, Masayasu, Wu, Di, Ho, Vincent T, Alonso, Anselmo, Hammond, Naa Norkor, Wong, Jessica, Sievers, Quinlan L, Brusic, Ana, McDonough, Sean M, Zeng, Wanyong, Perrin, Ann, Brown, Jennifer R, Canning, Christine M, Koreth, John, Cutler, Corey, Armand, Philippe, Neuberg, Donna, Lee, Jeng-Shin, Antin, Joseph H, Mulligan, Richard C, Sasada, Tetsuro, Ritz, Jerome, Soiffer, Robert J, Dranoff, Glenn, Alyea, Edwin P, Wu, Catherine J

“…Patients with advanced hematologic malignancies remain at risk for relapse following reduced-intensity conditioning (RIC) allogeneic hematopoietic stem cell…”
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CD40L-Tri, a novel formulation of recombinant human CD40L that effectively activates B cells by Naito, Masayasu, Hainz, Ursula, Burkhardt, Ute E., Fu, Buyin, Ahove, Deborah, Stevenson, Kristen E., Rajasagi, Mohini, Zhu, Baogong, Alonso, Anselmo, Witten, Elizabeth, Matsuoka, Ken-ichi, Neuberg, Donna, Duke-Cohan, Jonathan S., Wu, Catherine J., Freeman, Gordon J.

“…CD40L has a well-established role in enhancing the immunostimulatory capacity of normal and malignant B cells, but a formulation suitable for clinical use has…”
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Boosting leukemia-specific T cell responses in patients following stem cell transplantation by Burkhardt, Ute E, Wu, Catherine J

“…Whole tumor cell-based vaccines administered within the first 2 to 3 months after allogeneic stem cell transplantation stand out as a promising approach to…”
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Toward the next waves of cancer immunotherapy: 11th Annual Meeting of the Association for Cancer Immunotherapy (CIMT), Mainz, Germany, May 14–16, 2013 by Kloke, Björn-Philipp, Rae, Richard, Mahr, Andrea, Burkhardt, Ute E., Kvistborg, Pia, Britten, Cedrik M.

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IL-15 augments antitumoral activity of an ErbB2/HER2 cancer vaccine targeted to professional antigen-presenting cells by Burkhardt, Ute E., Sloots, Arjen, Jakobi, Vera, Wei, Wei-Zen, Cavallo, Federica, Kloke, Björn-Philipp, Wels, Winfried S.

“…Targeted delivery of tumor-associated antigens to professional antigen-presenting cells (APC) is being explored as a strategy to enhance the antitumoral…”
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Attentional Biases for Threatening Faces in Children: Vigilant and Avoidant Processes by Heim-Dreger, Uwe, Kohlmann, Carl-Walter, Eschenbeck, Heike, Burkhardt, Ute

“…The authors examined the processing of threat-related information in childhood anxiety with the emotional Stroop task and the dot probe task. In study 1, a…”
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DNA Vaccines Targeting Tumor Antigens to B7 Molecules on Antigen-Presenting Cells Induce Protective Antitumor Immunity and Delay Onset of HER-2/Neu-Driven Mammary Carcinoma by SLOOTS, Arjen, MASTINI, Cristina, ROHRBACH, Florian, WETH, Robert, CURCIO, Claudia, BURKHARDT, Ute, JÄGER, Elke, FORNI, Guido, CAVALLO, Federica, WELS, Winfried S

“…Purpose: Presentation of tumor antigens by professional antigen-presenting cells (APC) is critical for the induction of tumor-specific T-cell responses. To…”
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Role of phospholipases D1 and 2 in astroglial proliferation: effects of specific inhibitors and genetic deletion by Burkhardt, Ute, Beyer, Sandra, Klein, Jochen

“…Phospholipase D (PLD) activity has been linked to proliferation in many cell types including tumor cells. In the present study, we investigated the effects of…”
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Impaired brain development and reduced cognitive function in phospholipase D-deficient mice by Burkhardt, Ute, Stegner, David, Hattingen, Elke, Beyer, Sandra, Nieswandt, Bernhard, Klein, Jochen

“…•Genetic deletion of phospholipase D 1 or 2 delays brain development in mice.•Cognitive function is reduced in adult PLD-deficient mice.•PLD deficiency impairs…”
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Phospholipase D is a target for inhibition of astroglial proliferation by ethanol by Burkhardt, Ute, Wojcik, Bartosch, Zimmermann, Martina, Klein, Jochen

“…The proliferation of astrocytes during early brain development is driven by growth factors and is accompanied by the activation of phospholipase D (PLD)…”
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Hematologic malignancies: at the forefront of immunotherapeutic innovation by Bachireddy, Pavan, Burkhardt, Ute E., Rajasagi, Mohini, Wu, Catherine J.

“…The recent successes of cancer immunotherapy have stimulated interest for the potential widespread application of these approaches; hematologic malignancies…”
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Intranasal delivery of cells to the brain by Danielyan, Lusine, Schäfer, Richard, von Ameln-Mayerhofer, Andreas, Buadze, Marine, Geisler, Julia, Klopfer, Tim, Burkhardt, Ute, Proksch, Barbara, Verleysdonk, Stephan, Ayturan, Miriam, Buniatian, Gayane H., Gleiter, Christoph H., Frey, William H.

“…The safety and efficacy of cell-based therapies for neurodegenerative diseases depends on the mode of cell administration. We hypothesized that intranasally…”
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Developing Novel Approaches To Comprehensively Assess T Cell Repertoire Dynamics In The Early Post-Transplant Period by Burkhardt, Ute E., Kaplinsky, Joseph, Desmarais, Cindy, Stevenson, Kristen E., Alyea, Edwin P., Soiffer, Robert J., Ritz, Jerome, Neuberg, Donna S., Arnaout, Ramy, Wu, Catherine J.

“…Although allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a highly effective treatment modality for many hematologic malignancies, a major…”
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Literature and science: a different look inside neurodegeneration by Burkhardt, Ute, Lang, Dorothee, Mohr, Franziska, Schwarzkopf, Tina M, Zimmermann, Martina

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Autologous Whole Tumor Cell Vaccination Early After Allogeneic Stem Cell Transplantation Elicits Anti-Tumor T Cell Responses in Patients with Advanced Chronic Lymphocytic Leukemia (CLL) by Burkhardt, Ute E., Hainz, Ursula, Stevenson, Kristen E., Wu, Di, Ho, Vincent T., Goldstein, Natalie R., Pasek, Mildred, Brown, Jennifer R., Canning, Christine M, Koreth, John, Cutler, Corey, Armand, Philippe, Neuberg, Donna S., Antin, Joseph H., Sasada, Tetsuro, Ritz, Jerome, Dranoff, Glenn, Soiffer, Robert J., Alyea, Edwin P, Wu, Catherine J.

“…Abstract 1892▪▪This icon denotes a clinically relevant abstract Patients with advanced hematological malignancies remain at high risk for eventual disease…”
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Risk of iodine-induced thyrotoxicosis after coronary angiography: an investigation in 788 unselected subjects by Hintze, G, Blombach, O, Fink, H, Burkhardt, U, Kobberling, J

“…In this study, the risk of iodine-induced thyrotoxicosis in unselected patients from an iodine-deficient area was investigated. The patients were consecutively…”
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