Search Results - "BURKHARD, A"

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  1. 1

    Core principles of bacterial autoinducer systems by Hense, Burkhard A, Schuster, Martin

    Published in Microbiology and molecular biology reviews (01-03-2015)
    “…Autoinduction (AI), the response to self-produced chemical signals, is widespread in the bacterial world. This process controls vastly different target…”
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    A Mathematical Model of Quorum Sensing Induced Biofilm Detachment by Emerenini, Blessing O, Hense, Burkhard A, Kuttler, Christina, Eberl, Hermann J

    Published in PloS one (21-07-2015)
    “…Cell dispersal (or detachment) is part of the developmental cycle of microbial biofilms. It can be externally or internally induced, and manifests itself in…”
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  3. 3

    Oxetanes as Versatile Elements in Drug Discovery and Synthesis by Burkhard, Johannes A., Wuitschik, Georg, Rogers-Evans, Mark, Müller, Klaus, Carreira, Erick M.

    Published in Angewandte Chemie International Edition (22-11-2010)
    “…Sizable resources, both financial and human, are invested each year in the development of new pharmaceutical agents. However, despite improved techniques, the…”
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  4. 4

    Opinion: Does efficiency sensing unify diffusion and quorum sensing? by Hense, Burkhard A, Kuttler, Christina, Mueller, Johannes, Rothballer, Michael, Hartmann, Anton, Kreft, Jan-Ulrich

    Published in Nature reviews. Microbiology (01-03-2007)
    “…Quorum sensing faces evolutionary problems from non-producing or over- producing cheaters. Such problems are circumvented in diffusion sensing, an alternative…”
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  5. 5

    Moving Forward and Making a Difference: Research Priorities for the Science of Service by Ostrom, Amy L., Bitner, Mary Jo, Brown, Stephen W., Burkhard, Kevin A., Goul, Michael, Smith-Daniels, Vicki, Demirkan, Haluk, Rabinovich, Elliot

    Published in Journal of service research : JSR (01-02-2010)
    “…Given the significant, sustained growth in services experienced worldwide, Arizona State University’s Center for Services Leadership embarked on an 18-month…”
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  6. 6

    Why Quorum Sensing Controls Private Goods by Schuster, Martin, Sexton, D Joseph, Hense, Burkhard A

    Published in Frontiers in microbiology (19-05-2017)
    “…Cell-cell communication, also termed quorum sensing (QS), is a widespread process that coordinates gene expression in bacterial populations. The generally…”
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  7. 7

    Does efficiency sensing unify diffusion and quorum sensing? by Hense, Burkhard A, Kreft, Jan-Ulrich, Kuttler, Christina, Müller, Johannes, Rothballer, Michael, Hartmann, Anton

    Published in Nature reviews. Microbiology (01-03-2007)
    “…Quorum sensing faces evolutionary problems from non-producing or over-producing cheaters. Such problems are circumvented in diffusion sensing, an alternative…”
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    Simulation-Based Exploration of Quorum Sensing Triggered Resistance of Biofilms to Antibiotics by Ghasemi, Maryam, Hense, Burkhard A., Eberl, Hermann J., Kuttler, Christina

    Published in Bulletin of mathematical biology (01-07-2018)
    “…We present a mathematical model of biofilm response to antibiotics, controlled by a quorum sensing system that confers increased resistance. The model is a…”
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  10. 10

    Synthesis of Azaspirocycles and their Evaluation in Drug Discovery by Burkhard, Johannes A, Wagner, Björn, Fischer, Holger, Schuler, Franz, Müller, Klaus, Carreira, Erick M

    Published in Angewandte Chemie (International ed.) (03-05-2010)
    “…Make it spiro! Readily synthesized heteroatom‐substituted spiro[3.3]heptanes generally show higher aqueous solubility than their cyclohexane analogues, and…”
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    Expanding the Azaspiro[3.3]heptane Family: Synthesis of Novel Highly Functionalized Building Blocks by Burkhard, Johannes A, Guérot, Carine, Knust, Henner, Carreira, Erick M

    Published in Organic letters (06-01-2012)
    “…The preparation of versatile azaspiro[3.3]heptanes carrying multiple exit vectors is disclosed. Expedient synthetic routes enable the straightforward access to…”
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  14. 14

    Synthesis and Stability of Oxetane Analogs of Thalidomide and Lenalidomide by Burkhard, Johannes A, Wuitschik, Georg, Plancher, Jean-Marc, Rogers-Evans, Mark, Carreira, Erick M

    Published in Organic letters (06-09-2013)
    “…Oxetanes are used in drug discovery to enable physicochemical and metabolic property enhancement for the structures to which they are grafted. An imide CO to…”
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  15. 15

    Cascade Formation of Isoxazoles: Facile Base-Mediated Rearrangement of Substituted Oxetanes by Burkhard, Johannes A., Tchitchanov, Boris H., Carreira, Erick M.

    Published in Angewandte Chemie International Edition (27-05-2011)
    “…Give me five! Nitro compounds and oxetan‐3‐one react through an intriguing cascade sequence to give isoxazole‐4‐carbaldehydes using inexpensive reagents in a…”
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    Evolutionary Stabilization of Cooperative Toxin Production through a Bacterium-Plasmid-Phage Interplay by Spriewald, Stefanie, Stadler, Eva, Hense, Burkhard A., Münch, Philipp C., McHardy, Alice C., Weiss, Anna S., Obeng, Nancy, Müller, Johannes, Stecher, Bärbel

    Published in mBio (21-07-2020)
    “…Bacteria are excellent model organisms to study mechanisms of social evolution. The production of public goods, e.g., toxin release by cell lysis in clonal…”
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  18. 18

    Differential Equations Models to Study Quorum Sensing by Pérez-Velázquez, Judith, Hense, Burkhard A

    “…Mathematical models to study quorum sensing (QS) have become an important tool to explore all aspects of this type of bacterial communication. A wide spectrum…”
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  19. 19

    Synthesis and Structural Analysis of a New Class of Azaspiro[3.3]heptanes as Building Blocks for Medicinal Chemistry by Burkhard, Johannes A., Guérot, Carine, Knust, Henner, Rogers-Evans, Mark, Carreira, Erick M.

    Published in Organic letters (07-05-2010)
    “…Straightforward access toward previously unreported substituted, heterocyclic spiro[3.3]heptanes is disclosed. These spirocyclic systems may be considered as…”
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  20. 20

    Visual representations in knowledge management: framework and cases by Eppler, Martin J, Burkhard, Remo A

    Published in Journal of knowledge management (24-07-2007)
    “…Purpose - The purpose of this article is to explore the potential of visualization for corporate knowledge management.Design methodology approach - The…”
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