Search Results - "BURKE, Crystal W"

Quantifying dose-, strain-, and tissue-specific kinetics of parainfluenza virus infection by Pinky, Lubna, Burke, Crystal W, Russell, Charles J, Smith, Amber M

“…Human parainfluenza viruses (HPIVs) are a leading cause of acute respiratory infection hospitalization in children, yet little is known about how dose, strain,…”
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Identification and Characterization of Interferon-Induced Proteins That Inhibit Alphavirus Replication by Zhang, Yugen, Burke, Crystal W, Ryman, Kate D, Klimstra, William B

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Therapeutic monoclonal antibody treatment protects nonhuman primates from severe Venezuelan equine encephalitis virus disease after aerosol exposure by Burke, Crystal W, Froude, Jeffery W, Rossi, Franco, White, Charles E, Moyer, Crystal L, Ennis, Jane, Pitt, M Louise, Streatfield, Stephen, Jones, R Mark, Musiychuk, Konstantin, Kervinen, Jukka, Zeitlin, Larry, Yusibov, Vidadi, Glass, Pamela J

“…There are no FDA licensed vaccines or therapeutics for Venezuelan equine encephalitis virus (VEEV) which causes a debilitating acute febrile illness in humans…”
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Defining the Cynomolgus Macaque ( Macaca fascicularis ) Animal Model for Aerosolized Venezuelan Equine Encephalitis: Importance of Challenge Dose and Viral Subtype by Burke, Crystal W, Gardner, Christina L, Goodson, Aimee I, Piper, Ashley E, Erwin-Cohen, Rebecca A, White, Charles E, Glass, Pamela J

“…Venezuelan equine encephalitis virus (VEEV) outbreaks occur sporadically. Additionally, VEEV has a history of development as a biothreat agent. Yet, no…”
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Bivalent single domain antibody constructs for effective neutralization of Venezuelan equine encephalitis by Liu, Jinny L., Zabetakis, Dan, Gardner, Christina L., Burke, Crystal W., Glass, Pamela J., Webb, Emily M., Shriver-Lake, Lisa C., Anderson, George P., Weger-Lucarelli, James, Goldman, Ellen R.

“…Venezuelan equine encephalitis virus (VEEV) is a mosquito borne alphavirus which leads to high viremia in equines followed by lethal encephalitis and lateral…”
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Efficacy of Western, Eastern, and Venezuelan Equine Encephalitis (WEVEE) Virus-Replicon Particle (VRP) Vaccine against WEEV in a Non-Human Primate Animal Model by Burke, Crystal W., Erwin-Cohen, Rebecca A., Goodson, Aimee I., Wilhelmsen, Catherine, Edmundson, Jennifer A., White, Charles E., Glass, Pamela J.

“…The purpose of this study was to evaluate the effects of the route of administration on the immunogenicity and efficacy of a combined western, eastern, and…”
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Mode of parainfluenza virus transmission determines the dynamics of primary infection and protection from reinfection by Burke, Crystal W, Bridges, Olga, Brown, Sherri, Rahija, Richard, Russell, Charles J

“…Little is known about how the mode of respiratory virus transmission determines the dynamics of primary infection and protection from reinfection. Using…”
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Eastern and Venezuelan Equine Encephalitis Viruses Differ in Their Ability To Infect Dendritic Cells and Macrophages: Impact of Altered Cell Tropism on Pathogenesis by GARDNER, Christina L, BURKE, Crystal W, TESFAY, Mulu Z, GLASS, Pamela J, KLIMSTRA, William B, RYMAN, Kate D

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Syrian Hamsters Model Does Not Reflect Human-like Disease after Aerosol Exposure to Encephalitic Alphaviruses by Gardner, Christina L, Erwin-Cohen, Rebecca A, Lewis, Bridget S, Bakken, Russell R, Honnold, Shelley P, Glass, Pamela J, Burke, Crystal W

“…Venezuelan (VEE), eastern (EEE), and western (WEE) equine encephalitis viruses are encephalitic New World alphaviruses that cause periodic epizootic and…”
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Human-Like Neutralizing Antibodies Protect Mice from Aerosol Exposure with Western Equine Encephalitis Virus by Burke, Crystal W, Froude, Jeffrey W, Miethe, Sebastian, Hülseweh, Birgit, Hust, Michael, Glass, Pamela J

“…Western equine encephalitis virus (WEEV) causes symptoms in humans ranging from mild febrile illness to life-threatening encephalitis, and no human medical…”
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The utilization of advance telemetry to investigate critical physiological parameters including electroencephalography in cynomolgus macaques following aerosol challenge with eastern equine encephalitis virus by Trefry, John C, Rossi, Franco D, Accardi, Michael V, Dorsey, Brandi L, Sprague, Thomas R, Wollen-Roberts, Suzanne E, Shamblin, Joshua D, Kimmel, Adrienne E, Glass, Pamela J, Miller, Lynn J, Burke, Crystal W, Cardile, Anthony P, Smith, Darci R, Bavari, Sina, Authier, Simon, Pratt, William D, Pitt, Margaret L, Nasar, Farooq

“…Most alphaviruses are mosquito-borne and can cause severe disease in humans and domesticated animals. In North America, eastern equine encephalitis virus…”
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Similarities and Differences in Antagonism of Neuron Alpha/Beta Interferon Responses by Venezuelan Equine Encephalitis and Sindbis Alphaviruses by JUN YIN, GARDNER, Christina L, BURKE, Crystal W, RYMAN, Kate D, KLIMSTRA, William B

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The Immune Response to Eastern Equine Encephalitis Virus Acquired Through Organ Transplantation by Raabe, Vanessa, Lai, Lilin, Xu, Yong, Huerta, Chris, Wang, Dongli, Pouch, Stephanie M., Burke, Crystal W., Piper, Ashley E., Gardner, Christina L., Glass, Pamela J., Mulligan, Mark J.

“…The human immune response to eastern equine encephalitis virus (EEEV) infection is poorly characterized due to the rarity of infection. We examined the humoral…”
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Illumination of parainfluenza virus infection and transmission in living animals reveals a tissue-specific dichotomy by Burke, Crystal W, Mason, John N, Surman, Sherri L, Jones, Bart G, Dalloneau, Emilie, Hurwitz, Julia L, Russell, Charles J

“…The parainfluenza viruses (PIVs) are highly contagious respiratory paramyxoviruses and a leading cause of lower respiratory tract (LRT) disease. Since no…”
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Stabilization of a Broadly Neutralizing Anti-Chikungunya Virus Single Domain Antibody by Liu, Jinny L, Webb, Emily M, Zabetakis, Dan, Burke, Crystal W, Gardner, Christina L, Glass, Pamela J, Legler, Patricia M, Weger-Lucarelli, James, Anderson, George P, Goldman, Ellen R

“…A single domain antibody (clone CC3) previously found to neutralize a vaccine strain of the chikungunya virus (PRNT = 2. 5 ng/mL) was found to be broadly…”
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Heparan Sulfate Binding Can Contribute to the Neurovirulence of Neuroadapted and Nonneuroadapted Sindbis Viruses by RYMAN, Kate D, GARDNER, Christina L, BURKE, Crystal W, MEIER, Kathryn C, THOMPSON, Joseph M, KLIMSTRA, William B

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Interferon-alpha/beta deficiency greatly exacerbates arthritogenic disease in mice infected with wild-type chikungunya virus but not with the cell culture-adapted live-attenuated 181/25 vaccine candidate by Gardner, Christina L, Burke, Crystal W, Higgs, Stephen T, Klimstra, William B, Ryman, Kate D

“…Abstract In humans, chikungunya virus (CHIKV) infection causes fever, rash, and acute and persisting polyarthralgia/arthritis associated with joint swelling…”
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Vaccine elicitation and structural basis for antibody protection against alphaviruses by Sutton, Matthew S., Pletnev, Sergei, Callahan, Victoria, Ko, Sungyoul, Tsybovsky, Yaroslav, Bylund, Tatsiana, Casner, Ryan G., Cerutti, Gabriele, Gardner, Christina L., Guirguis, Veronica, Verardi, Raffaello, Zhang, Baoshan, Ambrozak, David, Beddall, Margaret, Lei, Hong, Yang, Eun Sung, Liu, Tracy, Henry, Amy R., Rawi, Reda, Schön, Arne, Schramm, Chaim A., Shen, Chen-Hsiang, Shi, Wei, Stephens, Tyler, Yang, Yongping, Florez, Maria Burgos, Ledgerwood, Julie E., Burke, Crystal W., Shapiro, Lawrence, Fox, Julie M., Kwong, Peter D., Roederer, Mario

“…Alphaviruses are RNA viruses that represent emerging public health threats. To identify protective antibodies, we immunized macaques with a mixture of western,…”
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Relationships among dissemination of primary parainfluenza virus infection in the respiratory tract, mucosal and peripheral immune responses, and protection from reinfection: a noninvasive bioluminescence-imaging study by Burke, Crystal W, Li, Mei, Hurwitz, Julia L, Vogel, Peter, Russell, Charles J

“…Respiratory paramyxoviruses such as respiratory syncytial virus (RSV) and human parainfluenza virus type 1 (HPIV1) to HPIV4 infect virtually all children by…”
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Characteristics of alpha/beta interferon induction after infection of murine fibroblasts with wild-type and mutant alphaviruses by Burke, Crystal W, Gardner, Christina L, Steffan, Joshua J, Ryman, Kate D, Klimstra, William B

“…Abstract We examined the characteristics of interferon alpha/beta (IFN-α/β) induction after alphavirus or control Sendai virus (SeV) infection of murine…”
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