Search Results - "BURGOYNE, P. S"

Absence of mDazl produces a final block on germ cell development at meiosis by Saunders, PT, Turner, JM, Ruggiu, M, Taggart, M, Burgoyne, PS, Elliott, D, Cooke, HJ

“…The autosomal gene DAZL is a member of a family of genes (DAZL, DAZ, BOULE), all of which contain a consensus RNA binding domain and are expressed in germ…”
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The meiotic checkpoint monitoring synapsis eliminates spermatocytes via p53-independent apoptosis by ODORISIO, T, RODRIGUEZ, T. A, EVANS, E. P, CLARKE, A. R, BURGOYNE, P. S

“…Evidence is accumulating that meiosis is subject to 'checkpoints' that monitor the quality of this complex process. In yeast, unresolved double strand breaks…”
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Modulation of the mouse testis transcriptome during postnatal development and in selected models of male infertility by Ellis, P.J.I., Furlong, R.A., Wilson, A., Morris, S., Carter, D., Oliver, G., Print, C., Burgoyne, P.S., Loveland, K.L., Affara, N.A.

“…The aim of this study is to develop an overview of genetic events during spermatogenesis using a novel, specifically targeted gonadal gene set. Two subtracted…”
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Hormonal and cellular regulation of Sertoli cell anti-Müllerian hormone production in the postnatal mouse by Al-Attar, L, Noël, K, Dutertre, M, Belville, C, Forest, M G, Burgoyne, P S, Josso, N, Rey, R

“…Anti-Müllerian hormone (AMH) is secreted by immature testicular Sertoli cells. Clinical studies have demonstrated a negative correlation between serum AMH and…”
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The Genetic Basis of XX-XY Differences Present before Gonadal Sex Differentiation in the Mouse [and Discussion] by Burgoyne, P. S., Thornhill, A. R., Boudrean, S. Kalmus, Darling, S. M., Bishop, C. E., Evans, E. P., Capel, B., Mittwoch, U.

“…There is now a substantial body of data showing that in eutherian mammals (mouse, rat, cow and man) XY conceptuses are developmentally more advanced (and…”
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Timing of Mating, Developmental Asynchrony and the Sex Ratio in Mice by Krackow, S, Burgoyne, P.S

“…Krackow, S. and P. S. Burgoyne. Timing of mating, developmental asynchrony and the sex ratio in mice. PHYSIOL BEHAV 63(1): 81–84, 1998.—According to the…”
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M31 and macroH2A1.2 colocalise at the pseudoautosomal region during mouse meiosis by Turner, J M, Burgoyne, P S, Singh, P B

“…Progression through meiotic prophase is associated with dramatic changes in chromosome condensation. Two proteins that have been implicated in effecting these…”
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A Y-chromosomal effect on blastocyst cell number in mice by BURGOYNE, P. S

“…Karyotopic and cell number analysis of 3.5 day post coitum preimplantation mouse embryos was used to determine whether XY embryos had more cells than XX…”
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BRCA1, Histone H2AX Phosphorylation, and Male Meiotic Sex Chromosome Inactivation by Turner, James M.A., Aprelikova, Olga, Xu, Xiaoling, Wang, Ruihong, Kim, Sangsoo, Chandramouli, Gadisetti V.R., Barrett, J.Carl, Burgoyne, Paul S., Deng, Chu-Xia

“…In mammalian spermatogenesis, the X and Y chromosomes are transcriptionally silenced during the pachytene stage of meiotic prophase (meiotic sex chromosome…”
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A paternally imprinted X chromosome retards the development of the early mouse embryo by THORNHILL, A. R, BURGOYNE, P. S

“…It has previously been shown that XO mouse fetuses with a paternally derived X chromosome (Xp) are developmentally retarded and consequently smaller than their…”
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Fertility in mice requires X-Y pairing and a Y-chromosomal "spermiogenesis" gene mapping to the long arm by Burgoyne, P S, Mahadevaiah, S K, Sutcliffe, M J, Palmer, S J

“…There is accumulating evidence that the mammalian Y chromosome, in addition to its testis-determining function, may have other male limited functions,…”
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Are XX and XY brain cells intrinsically different? by Arnold, Arthur P, Burgoyne, Paul S

“…In mammals and birds, the sex of the gonads is determined by genes on the sex chromosomes. For example, the mammalian Y-linked gene Sry causes testis…”
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A Model System for Study of Sex Chromosome Effects on Sexually Dimorphic Neural and Behavioral Traits by De Vries, Geert J, Rissman, Emilie F, Simerly, Richard B, Yang, Liang-Yo, Scordalakes, Elka M, Auger, Catherine J, Swain, Amanda, Lovell-Badge, Robin, Burgoyne, Paul S, Arnold, Arthur P

“…We tested the hypothesis that genes encoded on the sex chromosomes play a direct role in sexual differentiation of brain and behavior. We used mice in which…”
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Evidence that postnatal growth retardation in XO mice is due to haploinsufficiency for a non-PAR X gene by Burgoyne, P S, Ojarikre, O A, Turner, J M A

“…XO Turner women, irrespective of the parental source of the X chromosome, are of short stature, and this is now thought to be largely a consequence of…”
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Paternal Transmission of X-Linked Placental Dysplasia in Mouse Interspecific Hybrids by Zechner, U, Reule, M, Burgoyne, P. S, Schubert, A, Orth, A, Hameister, H, Fundele, R

“…It has previously been shown that abnormal placental development, i.e., hyper- and hypoplasia, occurs in crosses and backcrosses between different mouse (Mus)…”
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Recombinational DNA double-strand breaks in mice precede synapsis by Turner, James M.A, Jasin, Maria, Bonner, William M, Baudat, Frédéric, Blanco-Rodríguez, Josefa, Rogakou, Emmy P, de Boer, Peter, Mahadevaiah, Shantha K, Keeney, Scott, Burgoyne, Paul S

“…In Saccharomyces cerevisiae, meiotic recombination is initiated by Spo11-dependent double-strand breaks (DSBs), a process that precedes homologous synapsis…”
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Sex differences in sex chromosome gene expression in mouse brain by Xu, Jun, Burgoyne, Paul S., Arnold, Arthur P.

“…A major question is whether genes encoded on the sex chromosomes act directly in non-gonadal tissues to cause sex differences in development or function, or…”
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Tdy-negative XY, XXY and XYY female mice: breeding data and synaptonemal complex analysis by Mahadevaiah, S K, Lovell-Badge, R, Burgoyne, P S

“…In this paper we have compared the breeding performance of Tdy -negative XY, XXY and XYY females to assess the relative importance of the lack of a second X…”
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The Y rearrangement in mice: new insights into a perplexing PAR by Burgoyne, P S, Mahadevaiah, S K, Perry, J, Palmer, S J, Ashworth, A

“…In essence, the Y* rearrangement in the mouse is a Y chromosome that has been hijacked by a non-Y centromere attached distal to the pseudoautosomal region…”
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Evidence that sex chromosome asynapsis, rather than excess Y gene dosage, is responsible for the meiotic impairment of XYY mice by Rodriguez, T A, Burgoyne, P S

“…There is extensive evidence for the existence of a meiotic checkpoint that acts to eliminate spermatocytes that fail to achieve full sex chromosome synapsis at…”
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