Search Results - "BURGMAN, Paul"

Hypersensitivity of Ku80-Deficient Cell Lines and Mice to DNA Damage: The Effects of Ionizing Radiation on Growth, Survival, and Development by Nussenzweig, Andre, Sokol, Karen, Burgman, Paul, Li, Ligeng, Li, Gloria C.

“…We recently have shown that mice deficient for the 86-kDa component (Ku80) of the DNA-dependent protein kinase exhibit growth retardation and a profound…”
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Detecting changes in tumor hypoxia with carbonic anhydrase IX and pimonidazole by Shin, Kyung Hwan, Diaz-Gonzalez, Juan A, Russell, James, Chen, Qing, Burgman, Paul, Li, Xiao-Feng, Ling, C. Cliffton

“…We have used immunohistochemistry to examine the dynamics of tumor hypoxia. Expression of CAIX is known to be influenced by tumor hypoxia, and this protein has…”
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In vivo19F Magnetic Resonance Spectroscopy and Chemical Shift Imaging of Tri-Fluoro-Nitroimidazole as a Potential Hypoxia Reporter in Solid Tumors by PROCISSI, Daniel, CLAUS, Filip, BURGMAN, Paul, KOZIOROWSKI, Jacek, CHAPMAN, J. Donald, THAKUR, Sunitha B, MATEI, Cornelia, LING, C. Clifton, KOUTCHER, Jason A

“…Purpose: 2-Nitro-α-[(2,2,2-trifluoroethoxy)methyl]-imidazole-1-ethanol (TF-MISO) was investigated as a potential noninvasive marker of tissue oxygen levels in…”
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A Constitutive Heat Shock Element-binding Factor Is Immunologically Identical to the Ku Autoantigen (∗) by Kim, Dooha, Ouyang, Honghai, Yang, Shao-Hua, Nussenzweig, Andre, Burgman, Paul, Li, Gloria C.

“…Analysis of the heat shock element (HSE)-binding proteins in extracts of rodent cells, during heat shock and their post-heat shock recovery, indicates that the…”
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Assessment of regional tumor hypoxia using 18F-fluoromisonidazole and 64Cu(II)-diacetyl-bis(N4-methylthiosemicarbazone) positron emission tomography: Comparative study featuring microPET imaging, Po2 probe measurement, autoradiography, and fluorescent microscopy in the R3327-AT and FaDu rat tumor models by O'Donoghue, Joseph A, Zanzonico, Pat, Pugachev, Andrei, Wen, Bixiu, Smith-Jones, Peter, Cai, Shangde, Burnazi, Eva, Finn, Ronald D, Burgman, Paul, Ruan, Shutian, Lewis, Jason S, Welch, Michael J, Ling, C Clifton, Humm, John L

“…To compare two potential positron emission tomography (PET) tracers of tumor hypoxia in an animal model. The purported hypoxia imaging agents…”
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Thermal Protein Denaturation and Protein Aggregation in Cells Made Thermotolerant by Various Chemicals: Role of Heat Shock Proteins by Kampinga, Harm H., Brunsting, Jeanette F., Stege, Gerard J.J., Burgman, Paul W.J.J., Konings, Antonius W.T.

“…Thermotolerance (TT) induced by sodium arsenite (A-TT: 100 μ M, 1 h, 37°C), ethanol (E-TT: 6% (v/v), 25 min, 37°C), and diamide (D-TT: 300 μ M, 1 h, 37°C) was…”
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Hypoxia-inducible factor-1 drives annexin A2 system-mediated perivascular fibrin clearance in oxygen-induced retinopathy in mice by Huang, Bihui, Deora, Arun B., He, Kai-Li, Chen, Kang, Sui, Guangzhi, Jacovina, Andrew T., Almeida, Dena, Hong, Peng, Burgman, Paul, Hajjar, Katherine A.

“…Oxygen-induced retinopathy (OIR) is a well-characterized model for retinopathy of prematurity, a disorder that results from rapid microvascular proliferation…”
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The effect of DN (dominant-negative) Ku70 and reoxygenation on hypoxia cell-kill: Evidence of hypoxia-induced potentially lethal damage by Urano, Muneyasu, Li, Gloria C., He, Fuqiu, Minami, Akiko, Burgman, Paul, Ling, C. Clifton

“…Purpose: To study the effect of DN (dominant-negative) Ku70 and reoxygenation on the hypoxia-induced cell-kill. Materials and methods: Cell lines were human…”
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Cell line-dependent differences in uptake and retention of the hypoxia-selective nuclear imaging agent Cu-ATSM by Burgman, Paul, O'Donoghue, Joseph A., Lewis, Jason S., Welch, Michael J., Humm, John L., Ling, C. Clifton

“…Cu-diacetyl-bis( N 4-methylthiosemicarbazone) [Cu-ATSM] is a potential marker for tumor hypoxia that has been under evaluation for clinical use. In this study,…”
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Hypoxia-Induced Increase in FDG Uptake in MCF7 Cells by Burgman, Paul, O'Donoghue, Joseph A, Humm, John L, Ling, C. Clifton

“…Recent clinical data indicate that tumor hypoxia negatively affects the treatment outcome of both radiotherapy and surgery in various cancers, emphasizing the…”
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Radiosynthesis of [131 I]IAZGP via nucleophilic substitution and its biological evaluation as a hypoxia marker — is specific activity a factor influencing hypoxia-mapping ability of a hypoxia marker? by Suehiro, Makiko, Burgman, Paul, Carlin, Sean, Burke, Sean, Yang, Guangbin, Ouerfelli, Ouathek, Oehler-Janne, Christoph, O'Donoghue, Joseph, Ling, Clifton, Humm, John

“…Abstract Introduction The hypoxia marker IAZGP, 1-(6-deoxy-6-iodo-β- d -galactopyranosyl)-2-nitroimidazole, has been labeled with123 I/124 I/125 I/131 I via…”
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A preclinical model for noninvasive imaging of hypoxia-induced gene expression; comparison with an exogenous marker of tumor hypoxia by Wen, Bixiu, Burgman, Paul, Zanzonico, Pat, O'donoghue, Joseph, Cai, Shangde, Finn, Ron, Serganova, Inna, Blasberg, Ronald, Gelovani, Juri, Li, Gloria C, Ling, C Clifton

“…Hypoxia is associated with tumor aggressiveness and is an important cause of resistance to radiation therapy and chemotherapy. Assays of tumor hypoxia could…”
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In vivo super(19)F Magnetic Resonance Spectroscopy and Chemical Shift Imaging of Tri-Fluoro-Nitroimidazole as a Potential Hypoxia Reporter in Solid Tumors by Procissi, Daniel, Claus, Filip, Burgman, Paul, Koziorowski, Jacek, Chapman, JDonald, Thakur, Sunitha B, Matei, Cornelia, Ling, CClifton, Koutcher, Jason A

“…PURPOSE: 2-Nitro- alpha -[(2,2,2-trifluoroethoxy)methyl]-imidazole-1-ethanol (TF-MISO) was investigated as a potential noninvasive marker of tissue oxygen…”
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In vivo 19F magnetic resonance spectroscopy and chemical shift imaging of tri-fluoro-nitroimidazole as a potential hypoxia reporter in solid tumors by Procissi, Daniel, Claus, Filip, Burgman, Paul, Koziorowski, Jacek, Chapman, J Donald, Thakur, Sunitha B, Matei, Cornelia, Ling, C Clifton, Koutcher, Jason A

“…2-Nitro-alpha-[(2,2,2-trifluoroethoxy)methyl]-imidazole-1-ethanol (TF-MISO) was investigated as a potential noninvasive marker of tissue oxygen levels in…”
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Heat inactivation of Ku autoantigen : Possible role in hyperthermic radiosensitization by BURGMAN, P, OUYANG, H, PETERSON, S, CHEN, D. J, LI, G. C

“…Heat shock prior, during, or immediately after ionizing radiation synergistically increases cell killing, a phenomenon termed hyperthermic radiosensitization…”
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Modulation of thermal induction of hsp70 expression by Ku autoantigen or its individual subunits by Yang, Shao-Hua, Nussenzweig, Andre, Li, Ligeng, Kim, Dooha, Ouyang, Honghai, Burgman, Paul, Li, Gloria C.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Suppression of Heat-Induced hsp70 Expression by the 70-kDa Subunit of the Human Ku Autoantigen by Li, Gloria C., Yang, Shao-Hua, Kim, Dooha, Nussenzweig, Andre, Ouyang, Honghai, Wei, June, Burgman, Paul, Li, Ligeng

“…Expression of the 70-kDa polypeptide of human Ku autoantigen in rat cells is shown to suppress specifically the induction of hsp70 upon heat shock. Thermal…”
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