Search Results - "BURGESS, Jason P."

NMR-Based Metabolomics Analysis Reproducibly Identifies Unique Subject-Specific Profiles That Change during Peanut Oral Immunotherapy by Vickery, Brian P., MD, FAAAAI, Kulis, Michael D., PhD, Stewart, Delisha, PhD, Pathmasiri, Wimal, PhD, Hamilton, Deanna K., RN, McRitchie, Susan, MS, Burgess, Jason P., PhD, Sumner, Susan, PhD, Burks, A. Wesley, MD, FAAAAI

“…Results PCA of all samples demonstrated high reproducibility, with analytical variability less than biological variability at each time point and substantial…”
Get full text

A Hexacyclic ent-Trachylobane Diterpenoid Possessing an Oxetane Ring from Mitrephora glabra by Li, Chen, Lee, Dongho, Graf, Tyler N, Phifer, Sharnelle S, Nakanishi, Yuka, Burgess, Jason P, Riswan, Soedarsono, Setyowati, Fransisca M, Saribi, Achmad M, Soejarto, Djaja D, Farnsworth, Norman R, Falkinham, Joseph O, Kroll, David J, Kinghorn, A. Douglas, Wani, Mansukh C, Oberlies, Nicholas H

“…Three new ent-trachylobane diterpenoids (1−3) were isolated and structures elucidated from Mitrephora glabra Scheff. (Annonaceae). Mitrephorone A (1) possesses…”
Get full text

New colchicinoids from a native Jordanian meadow saffron, Colchicum brachyphyllum: isolation of the first naturally occurring dextrorotatory colchicinoid by Alali, F.Q, El-Elimat, T, Li, C, Qandil, A, Alkofahi, A, Tawaha, K, Burgess, J.P, Nakanishi, Y, Kroll, D.J, Navarro, H.A

“…As part of our continuing investigation of Jordanian Colchicum species, the biologically active components of Colchicum brachyphyllum were pursued. Using…”
Get full text

Identification of [14C]Fluasterone Metabolites in Urine and Feces Collected from Dogs after Subcutaneous and Oral Administration of [14C]Fluasterone by BURGESS, Jason P, GREEN, Jonathan S, HILL, Judith M, QIAO ZHAN, LINDEBLAD, Matthew, LYUBIMOV, Alexander, KAPETANOVIC, Izet M, SCHWARTZ, Arthur, THOMAS, Brian F

“…The objective of this research was the identification of the metabolic profile of fluasterone, a synthetic derivative of dehydroepiandrosterone, in dogs…”
Get full text

Serum trace metal association with response to erythropoiesis stimulating agents in incident and prevalent hemodialysis patients by Brier, Michael E., Gooding, Jessica R., Harrington, James M., Burgess, Jason P., McRitchie, Susan L., Zhang, Xiaolan, Rovin, Brad H., Klein, Jon B., Himmelfarb, Jonathan, Sumner, Susan J., Merchant, Michael L.

“…Alterations in hemodialysis patients’ serum trace metals have been documented. Early studies addressing associations levels of serum trace metals with…”
Get full text

Human PAH is characterized by a pattern of lipid-related insulin resistance by Hemnes, Anna R, Luther, J Matthew, Rhodes, Christopher J, Burgess, Jason P, Carlson, James, Fan, Run, Fessel, Joshua P, Fortune, Niki, Gerszten, Robert E, Halliday, Stephen J, Hekmat, Rezzan, Howard, Luke, Newman, John H, Niswender, Kevin D, Pugh, Meredith E, Robbins, Ivan M, Sheng, Quanhu, Shibao, Cyndya A, Shyr, Yu, Sumner, Susan, Talati, Megha, Wharton, John, Wilkins, Martin R, Ye, Fei, Yu, Chang, West, James, Brittain, Evan L

“…Pulmonary arterial hypertension (PAH) is a deadly disease of the small pulmonary vasculature with an increased prevalence of insulin resistance (IR). Insulin…”
Get full text

Metabolites as biomarkers of adverse reactions following vaccination: A pilot study using nuclear magnetic resonance metabolomics by McClenathan, Bruce M, Stewart, Delisha A, Spooner, Christina E, Pathmasiri, Wimal W, Burgess, Jason P, McRitchie, Susan L, Choi, Y. Sammy, Sumner, Susan C.J

“…Highlights • Metabolomics is the study of the small-molecule metabolite profile of an organism. • Metabolomics may help identify individuals predisposed to…”
Get full text

Reaction of the Butter Flavorant Diacetyl (2,3-Butanedione) with N-α-Acetylarginine: A Model for Epitope Formation with Pulmonary Proteins in the Etiology of Obliterative Bronchiolitis by Mathews, James M, Watson, Scott L, Snyder, Rodney W, Burgess, Jason P, Morgan, Daniel L

“…The butter flavorant diacetyl (2,3-butanedione) is implicated in causing obliterative bronchiolitis in microwave popcorn plant workers. Because diacetyl…”
Get full text

Cytotoxic Prenylated Xanthones and the Unusual Compounds Anthraquinobenzophenones from Cratoxylum sumatranum by Seo, Eun-Kyoung, Kim, Nam-Cheol, Wani, Mansukh C, Wall, Monroe E, Navarro, Hernán A, Burgess, Jason P, Kawanishi, Kazuko, Kardono, Leonardus B. S, Riswan, Soedarsono, Rose, William C, Fairchild, Craig R, Farnsworth, Norman R, Kinghorn, A. Douglas

“…Six new xanthones, cratoxyarborenones A−F (1−6), were isolated from the leaves, twigs, and/or stem bark of Cratoxylum sumatranum along with the known compound,…”
Get full text

Copper-Catalyzed Cyclization of Steroidal Acylaminoacetylenes:  Syntheses of Novel 11β-Aryl-17,17- spiro[(4‘H,5‘-methylene)oxazol]-Substituted Steroids by Jin, Chunyang, Burgess, Jason P, Kepler, John A, Cook, C. Edgar

“…A variety of novel 11β-aryl-17,17-spiro[(4‘H,5‘-methylene)oxazol]-substituted steroids have been synthesized in moderate to good yields via copper-catalyzed…”
Get full text

CB1 cannabinoid receptor‐phosphorylated fourth intracellular loop structure‐function relationships by Eldeeb, Khalil, Ganjiwale, Anjali D., Chandrashekaran, Indu R., Padgett, Lea W., Burgess, Jason P., Howlett, Allyn C., Cowsik, Sudha M.

“…A peptide comprising the juxtamembrane C‐terminal intracellular loop 4 (IL4) of the CB1 cannabinoid receptor possesses three serine residues (Ser402, Ser411,…”
Get full text

Caged Naloxone: Synthesis, Characterization, and Stability of 3‑O‑(4,5-Dimethoxy-2-nitrophenyl)carboxymethyl Naloxone (CNV-NLX) by Lewin, Anita H, Fix, Scott E, Zhong, Desong, Mayer, Louise D, Burgess, Jason P, Mascarella, S. Wayne, Reddy, P. Anantha, Seltzman, Herbert H, Carroll, F. Ivy

“…The photolabile analogue of the broad-spectrum opioid antagonist naloxone, 3-O-(4,5-dimethoxy-2-nitrophenyl)­carboxymethyl naloxone (also referred to as “caged…”
Get full text

Bioactive Constituents of the Roots of Licania intrapetiolaris by OBERLIES, Nicholas H., BURGESS, Jason P., NAVARRO, Hernán A., PINOS, Rosa Elena, SOEJARTO, Djaja D., FARNSWORTH, Norman R., KINGHORN, A. Douglas, WANI, Mansukh C., WALL, Monroe E.

“…Fractionation of a methanol extract of the roots of Licania intrapetiolaris, as directed by activity against the KB assay, has led to the isolation of two…”
Get full text

Metabolomics of urine for the assessment of microvesicular lipid accumulation in the liver following isoniazid exposure by Sumner, Susan J, Burgess, Jason P, Snyder, Rodney W, Popp, James A, Fennell, Timothy R

“…This study was conducted to develop a noninvasive marker of hepatic microvesicular lipid accumulation (MVLA), a histopathological effect currently diagnosed in…”
Get full text

Pyrrolizidine alkaloids from Echium glomeratum (Boraginaceae) by Alali, Feras Q., Tahboub, Yahya R., Ibrahim, Eyad S., Qandil, Amjad M., Tawaha, Khaled, Burgess, Jason P., Sy, Arlene, Nakanishi, Yuka, Kroll, David J., Oberlies, Nicholas H.

“…Five pyrrolizidine alkaloids were isolated from Echium glomeratum Poir. (Boraginaceae). Three of these were (7 S, 8 R)-petranine ( 1), (7 S, 8 S)-petranine (…”
Get full text

Conformationally Constrained Analogues of N-(Piperidinyl)-5-(4-Chlorophenyl)-1-(2,4- Dichlorophenyl)-4-Methyl-1H-Pyrazole-3-Carboxamide (SR141716): Design, Synthesis, Computational Analysis, And Biological Evaluations by Zhang, Yanan, Burgess, Jason P, Brackeen, Marcus, Gilliam, Anne, Mascarella, S. Wayne, Page, Kevin, Seltzman, Herbert H, Thomas, Brian F

“…Structure−activity relationships (SARs) of 1 (SR141716) have been extensively documented, however, the conformational properties of this class have received…”
Get full text

Novel Bioactive Clerodane Diterpenoids from the Leaves and Twigs of Casearia sylvestris by Oberlies, Nicholas H, Burgess, Jason P, Navarro, Hernán A, Pinos, Rosa Elena, Fairchild, Craig R, Peterson, Russell W, Soejarto, Djaja D, Farnsworth, Norman R, Kinghorn, A. Douglas, Wani, Mansukh C, Wall, Monroe E

“…Fractionation of a methanol extract of the leaves and twigs of Casearia sylvestris, as directed by activity against KB cell cytotoxicity, led to the isolation…”
Get full text

Metabolism and disposition of 2-methoxy-4-nitroaniline in male and female Harlan Sprague Dawley rats and B6C3F1/N mice by Mathews, James M., Zhan, Qiao, Etheridge, Amy S., Patel, Purvi R., Black, Sherry R., Banks, Troy T., Fennell, Timothy R., Snyder, Rodney W., Burgess, Jason P., Warren, Stephen D., Surh, Inok, Waidyanatha, Suramya

“…The disposition of 2-Methoxy-4-nitroaniline (MNA) was investigated in male and female Harlan Sprague Dawley rats and B6C3F1/N mice following oral, intravenous,…”
Get full text

Synthesis, nicotinic acetylcholine receptor binding, and pharmacological properties of 3′-(substituted phenyl)deschloroepibatidine analogs by Ivy Carroll, F., Yokota, Yasuno, Ma, Wei, Lee, Jeffrey R., Brieaddy, Lawrence E., Burgess, Jason P., Navarro, Hernán A., Damaj, M.I., Martin, Billy R.

“…A series of 3′-(substituted phenyl)deschloroepibatidine analogs ( 5a– j) were synthesized. The α4β2 ∗ and α7 nicotinic acetylcholine receptor (nAChR) binding…”
Get full text

Colchicinoids from Colchicum crocifolium Boiss. (Colchicaceae) by Alali, Feras Q., Gharaibeh, Ahmad A., Ghawanmeh, Abdullah, Tawaha, Khaled, Qandil, Amjad, Burgess, Jason P., Sy, Arlene, Nakanishi, Yuka, Kroll, David J., Oberlies, Nicholas H.

“…A new colchicinoid from Colchicum crocifolium Boiss. (Colchicaceae) was isolated and identified as N,N-dimethyl-N-deacetyl-(−)-cornigerine (5), along with four…”
Get full text