Search Results - "BURGER, J"

CXCR4 antagonists: targeting the microenvironment in leukemia and other cancers by Burger, J A, Peled, A

“…Hematopoietic and epithelial cancer cells express CXCR4, a seven-transmembrane G-protein-coupled chemokine receptor. Stromal cells within the bone marrow…”
Get full text

Understanding population changes in seabirds requires examining multiple causal factors and developing science‐based adaptive species conservation plans by Burger, J.

Get full text

Agglomerations and the rise of urban network externalities by Burger, Martijn J., Meijers, Evert J.

“…This paper introduces the theme of the special issue ‘Agglomerations and the Rise of Urban Network Externalities’. Urban network externalities are defined as…”
Get full text

Borrowing size in networks of cities: City size, network connectivity and metropolitan functions in Europe by Meijers, Evert J., Burger, Martijn J., Hoogerbrugge, Marloes M.

“…The current dynamics in the Western European urban system are in marked contrast with the bourgeoning literature stressing the importance of agglomeration for…”
Get full text

Neighborhood-Based social capital and life satisfaction: the case of Rotterdam, The Netherlands by Hoogerbrugge, Marloes M., Burger, Martijn J.

“…In this study, we examine the relationship between neighborhood-based social capital and residents' life satisfaction by considering resident heterogeneity…”
Get full text

The phosphoinositide-3-kinase (PI3K)-delta and gamma inhibitor, IPI-145 (Duvelisib), overcomes signals from the PI3K/AKT/S6 pathway and promotes apoptosis in CLL by Balakrishnan, K, Peluso, M, Fu, M, Rosin, N Y, Burger, J A, Wierda, W G, Keating, M J, Faia, K, O'Brien, S, Kutok, J L, Gandhi, V

“…The functional relevance of the B-cell receptor (BCR) and the evolution of protein kinases as therapeutic targets have recently shifted the paradigm for…”
Get full text

Spatial Structure and Productivity in US Metropolitan Areas by Meijers, Evert J, Burger, Martijn J

“…Recent concepts such as ‘megaregions' and ‘polycentric urban regions' emphasize that external economies are not confined to a single urban core, but are shared…”
Get full text

Anyons and the double copy by Burger, Daniel J, Emond, William T., Moynihan, Nathan

“…A bstract We examine the double copy structure of anyons in gauge theory and gravity. Using on-shell amplitude techniques, we construct little group covariant…”
Get full text

Higher incidence of patellar incongruence after under correction of pre-arthritic coronal alignment following medial unicompartmental knee arthroplasty by Ruderman, L. V., Bayoumi, T., Burger, J. A., Zuiderbaan, H. A., Pearle, A. D.

“…Purpose This study aimed to compare patellofemoral joint alignment of knees with restored pre-arthritic coronal alignment versus knees with under- or…”
Get full text

Modelling strategy and net employment effects of renewable energy and energy efficiency: A meta-regression by Stavropoulos, S., Burger, M.J.

“…By conducting a meta-analysis of the empirical literature on the net employment effects of renewable energy, we explore the extent to which the reported net…”
Get full text

Improved Outcomes for Responders After Treatment with Induction Chemotherapy and Chemo(re)irradiation for Locally Recurrent Rectal Cancer by Voogt, E. L. K., van Zoggel, D. M. G. I., Kusters, M., Nieuwenhuijzen, G. A. P., Bloemen, J. G., Peulen, H. M. U., Creemers, G. J. M., van Lijnschoten, G., Nederend, J., Roef, M. J., Burger, J. W. A., Rutten, H. J. T.

“…Background Despite improvements in the multimodality treatment for patients with locally recurrent rectal cancer (LRRC), oncological outcomes remain poor. This…”
Get full text

Locally recurrent rectal cancer; long-term outcome of curative surgical and non-surgical treatment of 447 consecutive patients in a tertiary referral centre by Hagemans, J.A.W., van Rees, J.M., Alberda, W.J., Rothbarth, J., Nuyttens, J.J.M.E., van Meerten, E., Verhoef, C., Burger, J.W.A.

“…The majority of patients with locally recurrent rectal cancer (LRRC) present with extensive metastatic disease or an unresectable recurrence, and will be…”
Get full text

Borrowed Size, Agglomeration Shadows and Cultural Amenities in North-West Europe by Burger, Martijn J., Meijers, Evert J., Hoogerbrugge, Marloes M., Tresserra, Jaume Masip

“…It has been argued that the concept of "borrowed size" is essential to understanding urban patterns and dynamics in North-West Europe. This paper…”
Get full text

Applying infectious clones and untargeted metabolite profiling to characterize citrus tristeza virus-induced stem pitting in citrus by Aldrich, D. J., Taylor, M., Bester, R., El-Mohtar, C. A., Burger, J. T., Maree, H. J.

“…Citrus tristeza virus (CTV) causes economically important stem pitting in sensitive citrus types however the exact mechanisms of stem pitting development in…”
Get full text

BTK inhibition results in impaired CXCR4 chemokine receptor surface expression, signaling and function in chronic lymphocytic leukemia by Chen, S-S, Chang, B Y, Chang, S, Tong, T, Ham, S, Sherry, B, Burger, J A, Rai, K R, Chiorazzi, N

“…Bruton’s tyrosine kinase (BTK) is involved in the regulation of B-cell growth, migration and adhesion. The importance of BTK in cell trafficking is emphasized…”
Get full text

Absence of the lactase-persistence-associated allele in early Neolithic Europeans by Burger, J, Kirchner, M, Bramanti, B, Haak, W, Thomas, M.G

“…Lactase persistence (LP), the dominant Mendelian trait conferring the ability to digest the milk sugar lactose in adults, has risen to high frequency in…”
Get full text

Extraversion Moderates the Relationship Between the Stringency of COVID-19 Protective Measures and Depressive Symptoms by Wijngaards, Indy, Sisouw de Zilwa, Sophie C. M., Burger, Martijn J.

“…From the start of the COVID-19 pandemic, psychologists are theorizing that, as compared to introverts, extraverts experience more profound negative social…”
Get full text

Extended follow-up and impact of high-risk prognostic factors from the phase 3 RESONATE study in patients with previously treated CLL/SLL by Brown, J R, Hillmen, P, O’Brien, S, Barrientos, J C, Reddy, N M, Coutre, S E, Tam, C S, Mulligan, S P, Jaeger, U, Barr, P M, Furman, R R, Kipps, T J, Cymbalista, F, Thornton, P, Caligaris-Cappio, F, Delgado, J, Montillo, M, DeVos, S, Moreno, C, Pagel, J M, Munir, T, Burger, J A, Chung, D, Lin, J, Gau, L, Chang, B, Cole, G, Hsu, E, James, D F, Byrd, J C

“…In the phase 3 RESONATE study, ibrutinib demonstrated superior progression-free survival (PFS), overall survival (OS) and overall response rate (ORR) compared…”
Get full text

Perioperative Systemic Therapy Versus Cytoreductive Surgery and HIPEC Alone for Resectable Colorectal Peritoneal Metastases: Patient-Reported Outcomes of a Randomized Phase II Trial by Bakkers, C., Rovers, K. P., Rijken, A., Simkens, G. A. A. M., Bonhof, C. S., Nienhuijs, S. W., Burger, J. W. A., Creemers, G. J. M., Brandt-Kerkhof, A. R. M., Tuynman, J. B., Aalbers, A. G. J., Wiezer, M. J., de Reuver, P. R., van Grevenstein, W. M. U., Hemmer, P. H. J., Punt, C. J. A., Tanis, P. J., Mols, F., de Hingh, I. H. J. T.

“…Background As part of a randomized phase II trial in patients with isolated resectable colorectal peritoneal metastases (CPMs), the present study compared…”
Get full text

The diagnostic accuracy of local staging in colon cancer based on computed tomography (CT): evaluating the role of extramural venous invasion and tumour deposits by van den Berg, K., Wang, S., Willems, J. M. W. E., Creemers, G. J., Roodhart, J. M. L., Shkurti, J., Burger, J. W. A., Rutten, H. J. T., Beets-Tan, R. G. H., Nederend, J.

“…Purpose The shift from adjuvant to neoadjuvant treatment in colon cancer demands the radiological selection of patients for systemic therapy. The aim of this…”
Get full text