Search Results - "BURBRIDGE, M. F"
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Biological and pharmacological characterisation of three models of human ovarian carcinoma established in nude mice: use of the CA125 tumour marker to predict antitumour activity
Published in International journal of oncology (01-12-1999)“…In an attempt to improve the relevance of human tumour xenografts to the clinical situation, we have established 3 models of human ovarian carcinoma (IGROV1,…”
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Experimental Antitumour Activity of S 16020-2 in a Panel of Human Tumours
Published in European journal of cancer (1990) (01-10-1997)“…The antitumour activity of S 16020-2, a new topoisomerase II inhibitor, was evaluated in comparison with doxorubicin against 13 human tumours, including colon…”
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The role of the matrix metalloproteinases during in vitro vessel formation
Published in Angiogenesis (London) (2002)“…Matrix metalloproteinases (MMPs) constitute a large family of extracellular matrix degrading proteases implicated in a number of physiological and pathological…”
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Improved quantification of angiogenesis in the rat aortic ring assay
Published in Angiogenesis (London) (2001)“…In vitro angiogenesis assays are essential for the identification of potential angiogenic agents and screening for pharmacological inhibitors. Among these…”
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The effect of extracellular pH on angiogenesis in vitro
Published in Angiogenesis (London) (1999)“…The microenvironment of the majority of solid tumours in which new vessels must grow and survive is acidic. Whilst recent reports suggest a role of the low…”
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Only a subset of Met-activated pathways are required to sustain oncogene addiction
Published in Science signaling (2009)“…Tumor onset and progression require the accumulation of many genetic and epigenetic lesions. In some cases, however, cancer cells rely on only one of these…”
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Decrease in survival threshold of quiescent colon carcinoma cells in the presence of a small molecule integrin antagonist
Published in Molecular pharmacology (01-06-2003)“…The role of adhesion molecules, such as alphav integrins, in the control of the survival of quiescent tumor cells is unclear. We used S 34961, a novel small…”
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