Search Results - "BUNDEY, R. A."

A novel, orally active LPA(1) receptor antagonist inhibits lung fibrosis in the mouse bleomycin model by Swaney, J S, Chapman, C, Correa, L D, Stebbins, K J, Bundey, R A, Prodanovich, P C, Fagan, P, Baccei, C S, Santini, A M, Hutchinson, J H, Seiders, T J, Parr, T A, Prasit, P, Evans, J F, Lorrain, D S

“…The aim of this study was to assess the potential of an antagonist selective for the lysophosphatidic acid receptor, LPA(1), in treating lung fibrosis We…”
Get full text

A novel, orally active LPA1 receptor antagonist inhibits lung fibrosis in the mouse bleomycin model by Swaney, JS, Chapman, C, Correa, LD, Stebbins, KJ, Bundey, RA, Prodanovich, PC, Fagan, P, Baccei, CS, Santini, AM, Hutchinson, JH, Seiders, TJ, Parr, TA, Prasit, P, Evans, JF, Lorrain, DS

“…Background and purpose:  The aim of this study was to assess the potential of an antagonist selective for the lysophosphatidic acid receptor, LPA1, in treating…”
Get full text

A novel, orally active LPA 1 receptor antagonist inhibits lung fibrosis in the mouse bleomycin model by Swaney, JS, Chapman, C, Correa, LD, Stebbins, KJ, Bundey, RA, Prodanovich, PC, Fagan, P, Baccei, CS, Santini, AM, Hutchinson, JH, Seiders, TJ, Parr, TA, Prasit, P, Evans, JF, Lorrain, DS

“…Background and purpose:  The aim of this study was to assess the potential of an antagonist selective for the lysophosphatidic acid receptor, LPA 1 , in…”
Get full text

Inhibition of receptor-mediated calcium responses by corticotrophin-releasing hormone in the CATH.a cell line by Bundey, R.A., Kendall, D.A.

“…A region of the brain believed to be important in the CNS response to stress is the locus coeruleus, the predominant site of noradrenergic cell bodies…”
Get full text

Compartmentation of G-protein-coupled receptors and their signalling components in lipid rafts and caveolae by Insel, P A, Head, B P, Patel, H H, Roth, D M, Bundey, R A, Swaney, J S

“…G-protein-coupled receptors (GPCRs) and post-GPCR signalling components are expressed at low overall abundance in plasma membranes, yet they evoke rapid,…”
Get more information

Agonist-Stimulated Neuropeptide and Catecholamine Release from Bovine Adrenal Chromaffin Cells by BUNDEY, R. A., TONEFF, T., POTTENGER, J., KENNEDY, B. P., ZIEGLER, M. G., HOOK, V. Y.

Get full text

An Investigation of Noradrenaline Uptake and Release by the CATH.a Cell Line by Bundey, Richard A., Jones, Philip G., Kendall, David A.

“…: The cell bodies of ascending noradrenergic neurons in the brain are located predominantly in the locus coeruleus. An in vitro model of locus coeruleus…”
Get full text

Corticosteroid Modulation of Signal Transduction in the CATH.a Cell Line by Bundey, Richard A., Iredale, Philip A., Kendall, David A.

“…: Noradrenergic neuronal networks originating in the locus coeruleus have been implicated in the stress response. In order to study this system in vitro, we…”
Get full text

Homologous and heterologous uncoupling of muscarinic M3 and α1B adrenoceptors to Gαq/11 in SH‐SY5Y human neuroblastoma cells by Bundey, R A, Nahorski, S R

“…The present study employed a [35S]‐GTPγS binding protocol in conjunction with immunoprecipitation (IP) of the Gα subunits to investigate the desensitization of…”
Get full text

12-Lipoxygenase in Opioid-Induced Delayed Cardioprotection: Gene Array, Mass Spectrometric, and Pharmacological Analyses by Patel, Hemal H, Fryer, Ryan M, Gross, Eric R, Bundey, Richard A, Hsu, Anna K, Isbell, Marilyn, Eusebi, Leonard O.V, Jensen, Roderick V, Gullans, Steven R, Insel, Paul A, Nithipatikom, Kasem, Gross, Garrett J

“…ABSTRACT—12-Lipoxygenase (12-LO) has been shown to be a factor in acute ischemic preconditioning (IPC) in the isolated rat heart; however, no studies have been…”
Get full text

Homologous and heterologous uncoupling of muscarinic M 3 and α 1B adrenoceptors to Gα q/11 in SH‐SY5Y human neuroblastoma cells by Bundey, R A, Nahorski, S R

“…The present study employed a [ 35 S]‐GTPγS binding protocol in conjunction with immunoprecipitation (IP) of the Gα subunits to investigate the desensitization…”
Get full text

Mice lacking P2Y sub(2) receptors have salt-resistant hypertension and facilitated renal Na super(+) and water reabsorption by Rieg, T, Bundey, R A, Chen, Y, Deschenes, G, Junger, W, Insel, P A, Vallon, V

“…Extracellular nucleotides (e.g., ATP) regulate many physiological and pathophysiological processes through activation of nucleotide (P2) receptors in the…”
Get full text

Homologous and heterologous uncoupling of muscarinic M3 and [alpha]1B adrenoceptors to G[alpha]q/11 in SH-SY5Y human neuroblastoma cells by Bundey, R A, Nahorski, S R

“…1. The present study employed a [(35)S]-GTPgammaS binding protocol in conjunction with immunoprecipitation (IP) of the Galpha subunits to investigate the…”
Get full text

Homologous and heterologous uncoupling of muscarinic M(3) and alpha(1B) adrenoceptors to Galpha(q/11) in SH-SY5Y human neuroblastoma cells by Bundey, R A, Nahorski, S R

“…1. The present study employed a [(35)S]-GTPgammaS binding protocol in conjunction with immunoprecipitation (IP) of the Galpha subunits to investigate the…”
Get full text

Nitric Oxide Inhibition of Adenylyl Cyclase Type 6 Activity Is Dependent upon Lipid Rafts and Caveolin Signaling Complexes by Ostrom, Rennolds S, Bundey, Richard A, Insel, Paul A

“…Several cell types, including cardiac myocytes and vascular endothelial cells, produce nitric oxide (NO) via both constitutive and inducible isoforms of NO…”
Get full text

Quantification of adenylyl cyclase messenger RNA by real-time polymerase chain reaction by Bundey, Richard A, Insel, Paul A

Get full text