Search Results - "BUKO, A. M"

Serum IL-17F does not predict poor response to IM IFNβ-1a in relapsing-remitting MS by BUSHNELL, S. E, ZHAO, Z, STEINMAN, L, MEDORI, R, STEBBINS, C. C, CADAVID, D, BUKO, A. M, WHALLEY, E. T, DAVIS, J. A, VERSAGE, E. M, RICHERT, J. R, AXTELL, R. C

“…There is a significant unmet need for serum biomarkers in relapsing-remitting multiple sclerosis (RRMS) that are predictive of therapeutic response to…”
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Cytochrome P450-mediated metabolism of the HIV-1 protease inhibitor ritonavir (ABT-538) in human liver microsomes by Kumar, G N, Rodrigues, A D, Buko, A M, Denissen, J F

“…The HIV-1 protease inhibitor ritonavir (ABT-538) undergoes cytochrome P450-mediated biotransformation in human liver microsomes to three major metabolites, Ml,…”
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Serum IL-17F does not predict poor response to IM IFN beta -1a in relapsing-remitting MS by Bushnell, SE, Zhao, Z, Stebbins, C C, Cadavid, D, Buko, A M, Whalley, E T, Davis, JA, Versage, E M, Richert, J R, Axtell, R C, Steinman, L, Medori, R

“…Objective: There is a significant unmet need for serum biomarkers in relapsing-remitting multiple sclerosis (RRMS) that are predictive of therapeutic response…”
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Metabolism And Disposition of the HIV-1 Protease Inhibitor Ritonavir (ABT-538) in Rats, Dogs, and Humans by DENISSEN, J. F, GRABOWSKI, B. A, JOHNSON, M. K, BUKO, A. M, KEMPF, D. J, THOMAS, S. B, SURBER, B. W

“…The metabolism and disposition of [ 14 C]ritonavir (ABT-538, NORVIR), a potent, orally active HIV-1 protease inhibitor, were investigated in male and female…”
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Characterization of a Posttranslational Fucosylation in the Growth Factor Domain of Urinary Plasminogen Activator by BUKO, A. M, KENTZER, E. J, PETROS, A, MENON, G, ZUIDERWEG, E. R. P, SARIN, V. K

“…A posttranslational modification site in natural and recombinant urinary-type plasminogen activators (urokinases; EC 3.4.21.31) has been localized to Thr-18,…”
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Group B streptococci inactivate complement component C5a by enzymic cleavage at the C-terminus by BOHNSACK, J. F, MOLLISON, K. W, BUKO, A. M, ASHWORTH, J. C, HILL, H. R

“…Incubation of recombinant human C5a (rC5a) with the 7360 strain of group B streptococci (GBS) destroyed the ability of rC5a to stimulate chemotaxis or…”
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Tiacumicins, a novel complex of 18-membered macrolides. II. Isolation and structure determination by Hochlowski, J E, Swanson, S J, Ranfranz, L M, Whittern, D N, Buko, A M, McAlpine, J B

“…A novel complex of Gram-positive antibiotics has been isolated from the fermentation broth and mycelium of Dactylosporangium aurantiacum subsp. hamdenesis…”
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Production of brominated tiacumicin derivatives by Hochlowski, J E, Jackson, M, Rasmussen, R R, Buko, A M, Clement, J J, Whittern, D N, McAlpine, J B

“…Several novel tiacumicin derivatives containing bromine have been produced by the addition of inorganic bromine to the fermentation both of Dactylosporangium…”
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Altromycins E, F, G, H and I; additional novel components of the altromycin complex by Brill, G M, Jackson, M, Whittern, D N, Buko, A M, Hill, P, Chen, R H, McAlpine, J B

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Phenelfamycins, a novel complex of elfamycin-type antibiotics. II. Isolation and structure determination by Hochlowski, J E, Buytendorp, M H, Whittern, D N, Buko, A M, Chen, R H, McAlpine, J B

“…A novel complex of elfamycin-type antibiotics has been isolated from submerged fermentation of either Streptomyces violaceoniger AB 999F-80 or Streptomyces…”
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Identification of a yellow impurity in aged samples of aqueous butamben suspension: evidence for the oxidative degradation of poly(ethylene glycol) by Ginsburg, E J, Stephens, D A, West, P R, Buko, A M, Robinson, D H, Li, L C, Bommireddi, A R

“…Butamben (butyl p-aminobenzoate) has been formulated to provide long-acting treatment for chronic pain. The suspension, which contains poly(ethylene glycol)…”
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Pacidamycins, a novel series of antibiotics with anti-Pseudomonas aeruginosa activity. II. Isolation and structural elucidation by Chen, R H, Buko, A M, Whittern, D N, McAlpine, J B

“…A novel class of antibiotics was isolated from cultures of Streptomyces coeruleorubidus strain AB 1183F-64. The antimicrobial activity of the pacidamycins is…”
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HPLC and PDMS analysis of cleavage products aid in the design of small, stable ANP analogues by Devine, Jr, E M, Buko, A M, Cepa, S P, Davidsen, S K, Holleman, W H, Marselle, C A, Opgenorth, T J, Rockway, T W, von Geldern, T W

“…The degradation of a prototypical small analogue of atrial natriuretic peptide (ANP) has been studied using HPLC and mass spectrometric techniques. These…”
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Altromycins, novel pluramycin-like antibiotics. II. Isolation and elucidation of structure by Brill, G M, McAlpine, J B, Whittern, D N, Buko, A M

“…A novel complex of Gram-positive antibiotics was produced from the fermentation of an actinomycete culture AB 1246E-26. The antibiotics were recovered from the…”
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Sequence-specific fragmentation from oligopeptides using plasma-desorption mass spectrometry by Buko, A M, Sarin, V K

“…252Cf plasma-desorption mass spectrometry (PDMS) has been demonstrated to provide sequence-specific fragmentation for several oligopeptides. The nature of the…”
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Coloradocin, an antibiotic from a new Actinoplanes. II. Identity with luminamicin and elucidation of structure by Rasmussen, R R, Scherr, M H, Whittern, D N, Buko, A M, McAlpine, J B

“…Coloradocin was isolated from a fermentation broth by adsorption onto Amberlite XAD-2. The activity was eluted in MeOH and purified by gel filtration on…”
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Coumamidines, new broad spectrum antibiotics of the cinodine type. II. Isolation and structural elucidation by Chen, R H, Whittern, D N, Buko, A M, McAlpine, J B

“…Two novel, isomeric compounds, coumamidines gamma 1 and gamma 2, were isolated from fermentations of an actinomycete. The structures were elucidated…”
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Unexpected behavior of quinolone sulfamates by various mass spectrometric ionization techniques by Cepa, S P, Hill, P, Buko, A M

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Peptide studies using a fast atom bombardment high field mass spectrometer and data system. 4. Disulfide-containing peptides by Buko, A M, Fraser, B A

“…Ten peptides containing one, two or three disulfides were examined to determine their behavior under fast atom bombardment (FAB) mass spectrometric conditions…”
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Sequence analysis of polypeptides by collision activated dissociation on a triple quadrupole mass spectrometer by Hunt, D F, Buko, A M, Ballard, J M, Shabanowitz, J, Giordani, A B

“…A new approach to the direct sequencing of oligopeptides in complex mixtures is described. Mixtures of [2Ho]/[2H3]-N-acetylated and N,O-permethylated peptides…”
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