Search Results - "BUIST, P. H"
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Characterization of the Regiochemistry and Cryptoregiochemistry of a Caenorhabditis elegans Fatty Acid Desaturase (FAT-1) Expressed in Saccharomyces cerevisiae
Published in Biochemistry (Easton) (03-10-2000)“…To characterize the fatty acid desaturase produced by the fat-1 gene from the nematode Caenorhabditis elegans, the functional expression of this enzyme was…”
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Mechanism of fatty acid desaturation: a bioorganic perspective
Published in Prostaglandins, leukotrienes and essential fatty acids (01-02-2003)“…The desaturation of long chain fatty acids is a ubiquitous transformation which plays a critical role in the biosynthesis of lipids. Of particular interest to…”
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Dihydroceramide delta(4) desaturase initiates substrate oxidation at C-4
Published in Journal of the American Chemical Society (16-05-2001)“…The intermolecular primary deuterium isotope effects on the individual C-H bond cleavage steps involved in dihydroceramide Delta(4) desaturation have been…”
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Cryptoregiochemical analysis of an unusual bacterial desaturation
Published in Bioorganic & medicinal chemistry letters (05-11-2001)“…The cryptoregiochemistry of the cold-induced Δ 5 desaturation of long chain fatty acids, as it occurs in Bacillus subtilis ATCC 23857, has been examined by…”
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Substrate specificity, regioselectivity and cryptoregiochemistry of plant and animal omega-3 fatty acid desaturases
Published in Biochemical Society transactions (01-12-2000)“…In order to define the substrate requirements, regiochemistry and cryptoregiochemistry of the omega-3 fatty acid desaturases involved in polyunsaturated fatty…”
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Bioorganic chemistry of plant lipid desaturation
Published in Phytochemistry reviews (01-01-2003)“…The desaturation of long-chain fatty acids is a ubiquitous biotransformation which plays a critical role in the biosynthesis of plant lipids. Species-specific…”
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Stereochemical analysis of sulfoxides obtained by diverted desaturation
Published in Journal of the American Chemical Society (01-06-1992)Get full text
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Mechanism of fatty acid desaturation in the green alga Chlorella vulgaris
Published in European journal of biochemistry (01-06-2001)“…The hypothesis that the Δ9 desaturase of Chlorella vulgaris might operate by a synchronous mechanism has been tested using a kinetic isotope effect (KIE)…”
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Fatty acid desaturases: selecting the dehydrogenation channel
Published in Natural product reports (01-04-2004)Get more information
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Stereochemical analysis of a quasisymmetrical dialkyl sulfoxide obtained by a diverted biodehydrogenation reaction
Published in Journal of the American Chemical Society (01-07-1991)Get full text
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Stereochemistry of 10-sulfoxidation catalyzed by a soluble Delta9 desaturase
Published in Organic & biomolecular chemistry (21-03-2010)“…The stereochemistry of castor stearoyl-ACP Delta(9) desaturase-mediated 10-sulfoxidation has been determined. This was accomplished by (19)F NMR analysis of a…”
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Gamma-linolenic acid biosynthesis: cryptoregiochemistry of delta6 desaturation
Published in Journal of organic chemistry (23-02-2001)“…The valuable nutraceutical gamma-linolenic acid (GLA, (6Z,9Z,12Z)-octadecatrienoic acid) is biosynthesized by a series of regio- and stereoselective…”
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Enantioselective sulfoxidation of a fatty acid analog by baker's yeast
Published in Journal of organic chemistry (01-10-1990)Get full text
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Fatty acid desaturation: variations on an oxidative theme
Published in Current Opinion in Chemical Biology (01-10-2002)“…Significant progress in our understanding of the mechanism of fatty acid desaturation has been achieved. The site of initial oxidation has been determined for…”
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Catalytic diversity of fatty acid desaturases
Published in Tetrahedron: asymmetry (20-09-2004)“…[Display omitted] The highly selective oxidation chemistry carried out by fatty acid desaturases is a potentially important source of novel biocatalytic…”
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Exploring the hydroxylation-dehydrogenation connection: novel catalytic activity of castor stearoyl-ACP Delta(9) desaturase
Published in Journal of the American Chemical Society (03-04-2002)“…The novel product profile obtained by incubating chiral fluorinated substrate analogues with castor stearoyl-ACP Delta(9) desaturase has been rationalized…”
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Configurational Analysis of Cyclopropyl Fatty Acids Isolated from Escherichia coli
Published in Organic letters (05-01-2006)“…The absolute configuration of methyl lactobacillate and its 9,10 homologue, both isolated from Escherichia coli B−ATCC 11303, was found to be 11R,12S and…”
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Delta super(1) super(1) desaturases of Trichoplusia ni and Spodoptera littoralis exhibit dual catalytic behaviour
Published in Insect biochemistry and molecular biology (01-10-2006)“…The Delta super(1) super(1) desaturases found in moths such as Spodoptera littoralis play a critical role in the biosynthesis of their sex pheromones. The…”
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