Search Results - "BUGNO, Marcin"
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mRNA vaccines encoding influenza virus hemagglutinin (HA) elicits immunity in mice from influenza A virus challenge
Published in PloS one (18-04-2024)“…Influenza viruses cause epidemics and can cause pandemics with substantial morbidity with some mortality every year. Seasonal influenza vaccines have…”
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2
Role of rubrerythrin in the oxidative stress response of Porphyromonas gingivalis
Published in Molecular microbiology (01-04-2002)“…Summary Rubrerythrins are non‐haem iron proteins that have been implicated in oxidative stress protection in anaerobic bacteria and archaea. However, up to…”
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3
A Novel Mechanism of Tissue Inhibitor of Metalloproteinases-1 Activation by Interleukin-1 in Primary Human Astrocytes
Published in The Journal of biological chemistry (17-11-2006)“…Reactive astrogliosis is the gliotic response to brain injury with activated astrocytes and microglia being the major effector cells. These cells secrete…”
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4
Parthenolide Inhibits Activation of Signal Transducers and Activators of Transcription (STATs) Induced by Cytokines of the IL-6 Family
Published in Biochemical and biophysical research communications (07-01-2000)“…Progression of inflammatory processes correlates with the release of cell-derived mediators from the local site of inflammation. These mediators, including…”
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5
Rapid and Efficient Inactivation of IL-6 Gingipains, Lysine- and Arginine-Specific Proteinases from Porphyromonas Gingivalis
Published in Biochemical and biophysical research communications (11-08-1999)“…Deregulation of the cytokine network is an important adaptation of pathogenic bacteria to modulate and evade a host immune response. Here we describe that IL-6…”
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6
The C‐terminal domains of the gingipain K polyprotein are necessary for assembly of the active enzyme and expression of associated activities
Published in Molecular microbiology (01-12-2004)“…Summary The Porphyromonas gingivalis lysine‐specific cysteine protease (gingipain K, Kgp) is expressed as a large precursor protein consisting of a leader…”
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7
Porphyromonas gingivalis DPP-7 Represents a Novel Type of Dipeptidylpeptidase
Published in The Journal of biological chemistry (02-03-2001)“…A novel dipeptidylpeptidase (DPP-7) was purified from the membrane fraction of Porphyromonas gingivalis.This enzyme, with an apparent molecular mass of 76 kDa,…”
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8
Proteolysis of interleukin-6 receptor (IL-6R) by Porphyromonas gingivalis cysteine proteinases (gingipains) inhibits interleukin-6-mediated cell activation
Published in Microbial pathogenesis (01-04-2002)“…Current consensus is that periodontitis is an infectious disease in which a deregulated chronic inflammatory reaction not only may lead to periodontal tissue…”
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9
mRNA vaccines encoding influenza virus hemagglutinin
Published in PloS one (18-04-2024)“…Influenza viruses cause epidemics and can cause pandemics with substantial morbidity with some mortality every year. Seasonal influenza vaccines have…”
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10
Integration of high‐throughput analytics and cell imaging enables direct early productivity and product quality assessment during Chinese Hamster ovary cell line development for a complex multi‐subunit vaccine antigen
Published in Biotechnology progress (01-03-2020)“…Mammalian cell line generation typically includes stable pool generation, single cell cloning and several rounds of clone selection based on cell growth,…”
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11
Prolyl Tripeptidyl Peptidase from Porphyromonas gingivalis
Published in The Journal of biological chemistry (02-04-1999)“…Porphyromonas gingivalis possesses a complex proteolytic system, which is essential for both its growth and evasion of host defense mechanisms. In this report…”
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12
Mechanism of Interleukin-1- and Tumor Necrosis Factor α-Dependent Regulation of the α1-Antichymotrypsin Gene in Human Astrocytes
Published in The Journal of neuroscience (15-10-2000)“…The expression of α 1 -antichymotrypsin (ACT) is significantly enhanced in affected brain regions in Alzheimer's disease. This serine proteinase inhibitor…”
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13
Emerging family of proline-specific peptidases of Porphyromonas gingivalis : Purification and characterization of serine dipeptidyl peptidase, a structural and functional homologue of mammalian prolyl dipeptidyl peptidase IV
Published in Infection and immunity (01-03-2000)“…Porphyromonas gingivalis is an asaccharolytic and anaerobic bacterium that possesses a complex proteolytic system which is essential for its growth and evasion…”
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14
Prolyl tripeptidyl peptidase from Porphyromonas gingivalis. A novel enzyme with possible pathological implications for the development of periodontitis
Published in The Journal of biological chemistry (02-04-1999)“…Porphyromonas gingivalis possesses a complex proteolytic system, which is essential for both its growth and evasion of host defense mechanisms. In this report…”
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15
Identification of the interleukin-6/oncostation M response element in the rat tissue inhibitor of metalloproteinases-1 (TIMP-1)Promoter
Published in Nucleic acids research (1995)“…The rat tissue inhibitor of metalloproteinases 1 (TIMP-1) gene is expressed in rat hepatocytes, and this expression Is up-regulated by interieukln 6 (IL-6). We…”
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16
Reprogramming of TIMP-1 and TIMP-3 expression profiles in brain microvascular endothelial cells and astrocytes in response to proinflammatory cytokines
Published in FEBS letters (02-04-1999)“…Cytokine-dependent regulation of tissue inhibitors of metalloproteinases (TIMPs) expression provides an important mechanism for controlling the activity of…”
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17
Differential effects of oncostatin M and leukaemia inhibitory factor expression in astrocytoma cells
Published in Biochemical journal (15-04-2001)“…The effects of the production of two closely related cytokines, oncostatin M (OSM) and leukaemia inhibitory factor (LIF), by astrocytoma cells were…”
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18
Emerging Family of Proline-Specific Peptidases ofPorphyromonas gingivalis: Purification and Characterization of Serine Dipeptidyl Peptidase, a Structural and Functional Homologue of Mammalian Prolyl Dipeptidyl Peptidase IV
Published in Infection and Immunity (01-03-2000)“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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19
Mechanism of Interleukin-1- and Tumor Necrosis Factor alpha -Dependent Regulation of the alpha 1-Antichymotrypsin Gene in Human Astrocytes
Published in The Journal of neuroscience (15-10-2000)“…The expression of alpha(1)-antichymotrypsin (ACT) is significantly enhanced in affected brain regions in Alzheimer's disease. This serine proteinase inhibitor…”
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Journal Article -
20
Differential effects of oncostatin M and leukaemia inhibitory factor expression in astrocytoma cells
Published in Biochemical journal (15-04-2001)“…The effects of the production of two closely related cytokines, oncostatin M (OSM) and leukaemia inhibitory factor (LIF), by astrocytoma cells were…”
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