Search Results - "BUETOW, K. H"

High-Throughput Development and Characterization of a Genomewide Collection of Gene-Based Single Nucleotide Polymorphism Markers by Chip-Based Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry by Buetow, Kenneth H., Edmonson, Michael, MacDonald, Richard, Clifford, Robert, Yip, Ping, Kelley, Jenny, Little, Daniel P., Strausberg, Robert, Koester, Hubert, Cantor, Charles R., Braun, Andreas

“…We describe here a system for the rapid identification, assay development, and characterization of gene-based single nucleotide polymorphisms (SNPs). This…”
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Reliable identification of large numbers of candidate SNPs from public EST data by Buetow, Kenneth H, Edmonson, Michael N, Cassidy, Anna B

“…High-resolution genetic analysis of the human genome promises to provide insight into common disease susceptibility. To perform such analysis will require a…”
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Identification of inbred mouse strains harboring genetic modifiers of mammary tumor age of onset and metastatic progression by Lifsted, Traci, Le Voyer, Thomas, Williams, Max, Muller, William, Klein‐Szanto, Andres, Buetow, Kenneth H., Hunter, Kent W.

“…Metastasis is one of the most important and complex processes in human neoplastic disease. A large number of both positive and negative events must occur to…”
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Constitutional genetic variation at the human aromatase gene ( ) and breast cancer risk by SIEGELMANN-DANIELI, N, BUETOW, K

“…The activity of the aromatase enzyme, which converts androgens into oestrogens and has a major role in regulating oestrogen levels in the breast, is thought to…”
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The Cancer Genome Anatomy Project: building an annotated gene index by Strausberg, Robert L., Buetow, Kenneth H., Emmert-Buck, Michael R., Klausner, Richard D.

“…In 1997, the Vice President of the USA introduced the Cancer Genome Anatomy Project (CGAP) website, which aims to provide a publicly available annotated index…”
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Association of genetic variation of the transforming growth factor-alpha gene with cleft lip and palate by ARDINGER, H. H, BUETOW, K. H, BELL, G. I, BARDACH, J, VANDEMARK, D. R, MURRAY, J. C

“…Complex segregation analysis of pedigrees having nonsyndromic cleft lip with or without cleft palate (CL/P) (Chung et al. 1986; Marazita et al. 1986) has shown…”
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Loss of Heterozygosity Suggests Tumor Suppressor Gene Responsible for Primary Hepatocellular Carcinoma by Buetow, K. H., Murray, J. C., Israel, J. L., London, W. T., Smith, M., Kew, M., Blanquet, V., Brechot, C., Redeker, A., Govindarajah, S.

“…Primary hepatocellular carcinoma (PHC), epidemiologically associated with chronic hepatitis B virus (HBV) infection, has historically been felt to be caused by…”
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Influence of aberrant observations on high-resolution linkage analysis outcomes by BUETOW, K. H

“…Because of the availability of efficient, user-friendly computer analysis programs, the construction of multilocus human genetic maps has become commonplace…”
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Integrated human genome-wide maps constructed using the CEPH reference panel by Buetow, K.H, Weber, J.L, Ludwigsen, S, Scherpbier-Heddema, T, Duyk, G.M, Sheffield, V.C, Wang, Z.Y, Murray, J.C

“…High resolution linkage maps have proven to be invaluable tools in genetic investigations. We have assembled a collection of genetic maps constructed from…”
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A collection of tri- and tetranucleotide repeat markers used to generate high quality, high resolution human genome-wide linkage maps by Sheffield, V C, Weber, J L, Buetow, K H, Murray, J C, Even, D A, Wiles, K, Gastier, J M, Pulido, J C, Yandava, C, Sunden, S L

“…We report a collection of tri- and tetranucleotide repeat sequence polymorphic markers used to construct genome-wide human linkage maps. Using a strategy of…”
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Clinical and epidemiologic studies of cleft lip and palate in the Philippines by MURRAY, J. C, DAACK-HIRSCH, S, BUETOW, K. H, MUNGER, R, ESPINA, L, PAGLINAWAN, N, VILLANUEVA, E, RARY, J, MAGEE, K, MAGEE, W

“…Clinical and epidemiologic studies of defined geographic populations can serve as a means of establishing data important for genetic counseling and as a first…”
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An international database and integrated analysis tools for the study of cancer gene expression by STRAUSBERG, R. L, CAMARGO, A. A, SIMPSON, A. J. G, RIGGINS, G. J, SCHAEFER, C. F, DE SOUZA, S. J, GROUSE, L. H, LAL, A, BUETOW, K. H, BOON, K, GREENHUT, S. F

“…Researchers working collaboratively in Brazil and the United States have assembled an International Database of Cancer Gene Expression. Several strategies have…”
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Expression-based genetic/physical maps of single-nucleotide polymorphisms identified by the cancer genome anatomy project by Clifford, R, Edmonson, M, Hu, Y, Nguyen, C, Scherpbier, T, Buetow, K H

“…SNPs (Single-Nucleotide Polymorphisms), the most common DNA variant in humans, represent a valuable resource for the genetic analysis of cancer and other…”
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Studies of the candidate genes TGFB2, MSX1, TGFA, and TGFB3 in the etiology of cleft lip and palate in the Philippines by LIDRAL, A. C, MURRAY, J. C, BUETOW, K. H, BASART, A. M, SCHEARER, H, SHIANG, R, NAVAL, A, LAYDA, E, MAGEE, K, MAGEE, W

“…Population-based candidate-gene studies can be an effective strategy for identifying genes involved in the etiology of disorders where family-based linkage…”
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A single-gene explanation for the probability of having idiopathic talipes equinovarus by REBBECK, T. R, DIETZ, F. R, MURRAY, J. C, BUETOW, K. H

“…It has been hypothesized that the pathogenesis of idiopathic talipes equinovarus (ITEV, or clubfoot) is explained by genetic regulation of development and…”
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Susceptibility to Renal Carcinoma in the Eker Rat Involves a Tumor Suppressor Gene on Chromosome 10 by Yeung, Raymond S., Buetow, Kenneth H., Testa, Joseph R., Knudson, Alfred G.

“…Germ-line mutations of tumor suppressor genes confer strong predisposition to tumor formation. In the rat, a form of dominantly inherited renal carcinoma (RC)…”
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Error Filtration, Interference, and the Human Linkage Map by Shields, D. C., Collins, A., Buetow, K. H., Morton, N. E.

“…Typing error is a major problem in constructing human linkage maps, leading to incorrect orders and inflating map lengths. An error filter is incorporated into…”
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Survey of trinucleotide repeats in the human genome: assessment of their utility as genetic markers by Gastier, J M, Pulido, J C, Sunden, S, Brody, T, Buetow, K H, Murray, J C, Weber, J L, Hudson, T J, Sheffield, V C, Duyk, G M

“…Genetic markers based upon PCR amplification of short tandem repeat-containing sequence tagged sites (STSs) have become the standard for genetic mapping. We…”
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Asthma and Bronchial Hyperresponsiveness Linked to the XY Long Arm Pseudoautosomal Region by Holroyd, Kenneth J., Martinati, Laura C., Trabetti, Elisabetta, Scherpbier, Titia, Eleff, Scott M., Boner, Attilio L., Pignatti, Pier Franco, Kiser, Matthew B., Dragwa, Carl R., Hubbard, Frank, Sullivan, Christine D., Grasso, Luigi, Messler, Carol J., Huang, Minxue, Hu, Ying, Nicolaides, Nicholas C., Buetow, Kenneth H., Levitt, Roy C.

“…We examined the long arm XY pseudoautosomal region for linkage to asthma, serum IgE, and bronchial hyperresponsiveness. In 57 Caucasian families multipoint…”
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Multipoint gene mapping using seriation. I: General methods by BUETOW, K. H, CHAKRAVARTI, A

“…Initial and accurate inference of locus order and estimates of interlocus distances and interference can be obtained using seriation techniques. The analysis…”
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