Search Results - "BUENO DA COSTA, M. H"
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Large unilamellar vesicles as trehalose-stabilised vehicles for vaccines: storage time and in vivo studies
Published in Journal of controlled release (03-07-2000)“…Liposomes, as a pharmaceutical formulation must display a long shelf life. The recombinant heat-shock protein from Mycobacterium leprae (18-kDa hsp) or its…”
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Journal Article -
2
Microquantification of proteins with low chromophore content
Published in Biotechnology techniques (01-09-1997)“…The advantages of the intrinsic fluorescence of the tryptophan and the absorbance of the methionine residues of the 18 kDa-hsp - a recombinant protein from…”
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3
Lactic acid triggers, in vitro, thiomersal to degrade protein in the presence of PLGA microspheres
Published in International journal of pharmaceutics (01-04-2004)“…Microspheres of polymers like poly(lactic-co-glycolic acid) (PLGA) have been studied as a vehicle for controlled release vaccines. They require materials and…”
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4
Bioprocess design : Study of a case
Published in Biotechnology letters (1996)“…We developed a scale-up process design for the production of the 18 kDa heat shock recombinant protein from Mycobacterium leprae cloned in Saccharomyces…”
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Stabilisation of immunoconjugates by trehalose
Published in Biotechnology letters (01-03-2000)“…Stable immunoconjugates were prepared in the presence of 400 mM trehalose. Their residual activity after freeze-drying, rehydration and incubation for 9 h at…”
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