Search Results - "BUCY, R. P"

Antibody‐Mediated Rejection of Single Class I MHC‐Disparate Cardiac Allografts by Hattori, Y., Bucy, R. P., Kubota, Y., Baldwin III, W. M., Fairchild, R. L.

“…Murine CCR5−/− recipients produce high titers of antibody to complete MHC‐mismatched heart and renal allografts. To study mechanisms of class I MHC…”
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Preferential Priming of Alloreactive T Cells with Indirect Reactivity by Brennan, T. V., Jaigirdar, A., Hoang, V., Hayden, T., Liu, F.‐C., Zaid, H., Chang, C. K., Bucy, R. P., Tang, Q., Kang, S.‐M.

“…The relative contributions of the direct and indirect pathways in alloimmune responses have not been fully elucidated. We report a novel murine TCR transgenic…”
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The Potency of Allospecific Tregs Cells Appears to Correlate With T Cell Receptor Functional Avidity by Tsang, J. Y. S., Ratnasothy, K., Li, D., Chen, Y., Bucy, R. P., Lau, K. F., Smyth, L., Lombardi, G., Lechler, R., Tam, P. K. H.

“…CD4+CD25+ regulatory T cells (Treg cells) are an attractive adoptive cell therapy in mediating transplantation tolerance. T‐cell receptor (TcR) activation is…”
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Dextran sulfate sodium-induced colitis occurs in severe combined immunodeficient mice by Dieleman, L A, Ridwan, B U, Tennyson, G S, Beagley, K W, Bucy, R P, Elson, C O

“…Oral administration of dextran sulfate sodium (DSS) has been reported to induce colitis in mice. The purpose of this study was to determine whether the…”
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In situ hybridization with digoxigenin-labeled RNA probes: facts and artifacts by Panoskaltsis-Mortari, A, Bucy, R P

“…We have developed an easy, stream-lined yet sensitive protocol for in situ hybridization to mRNA in frozen tissue sections or cytospins using…”
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Immune Function in Patients with Rheumatoid Arthritis Treated with Etanercept by Moreland, L.W., Bucy, R.P., Weinblatt, M.E., Mohler, K.M., Spencer-Green, G.T., Chatham, W.W.

“…Etanercept, a recombinant human tumor necrosis factor (TNF) inhibitor that binds both soluble and cell-bound TNF, has been shown to reduce disease activity and…”
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Selective Gene Delivery to Head and Neck Cancer Cells via an Integrin Targeted Adenoviral Vector by KASONO, K, BLACKWELL, J. L, CURIEL, D. T, KRASNYKH, V, DOUGLAS, J. T, DMITRIEV, I, STRONG, T. V, REYNOLDS, P, KROPF, D. A, CARROLL, W. R, PETERS, G. E, BUCY, R. P

“…In vivo cancer gene therapy approaches for squamous cell carcinoma of the head and neck (SCCHN) based on adenoviral vector-mediated gene delivery have been…”
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Cyclosporin A-induced autoimmune disease in mice by Bucy, RP, Xu, XY, Li, J, Huang, G

“…The immunosuppressive drug cyclosporin A (CsA) disrupts the process of thymic ontogeny and repertoire selection in the alpha beta T cell population. Although…”
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Recurrence of the acute HIV syndrome after interruption of antiretroviral therapy in a patient with chronic HIV infection : A Case report by KILBY, J. Michael, GOEPFERT, Paul A, MILLER, Andrew P, GNANN, John W, SILLERS, Michael, SAAG, Michael S, BUCY, R. Pat

“…Clinical and virologic consequences of temporary interruption of HIV therapy are incompletely understood. To describe a febrile illness that was consistent…”
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Immune clearance of HIV type 1 replication-active cells: a model of two patterns of steady state HIV infection by Bucy, R P

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Single Cell Analysis of Cytokine Gene Coexpression During CD4+T-Cell Phenotype Development by Bucy, R. Pat, Karr, Laurel, Huang, Guo-Qiang, Li, Jimin, Carter, Denise, Honjo, Kazuhito, Lemons, James A., Murphy, Kenneth M., Weaver, Casey T.

“…CD4+T cells from αβ-T-cell receptor transgenic mice were analyzed for coexpression of cytokine mRNAs during phenotype development using a double-label in situ…”
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Perspectives on inducing efficient immune control of HIV-1 replication--a new goal for HIV therapeutics? by Bucy, R P, Kilby, J M

“…A goal for long-term therapy of HIV infection is immune control of virus replication rather than the somewhat unrealistic aim of complete viral elimination…”
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Characterization of avian natural killer cells and their intracellular CD3 protein complex by Göbel, T W, Chen, C L, Shrimpf, J, Grossi, C E, Bernot, A, Bucy, R P, Auffray, C, Cooper, M D

“…Natural killer (NK) cell activity appears to be conserved throughout vertebrate development but NK cells have only been well characterized in mammals…”
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Transductional Efficacy and Safety of an Intraperitoneally Delivered Adenovirus Encoding an Anti-erbB-2 Intracellular Single-Chain Antibody for Ovarian Cancer Gene Therapy by Deshane, Jessy, Siegal, Gene P., Wang, Minghui, Wright, Marci, Bucy, R.Pat, Alvarez, Ronald D., Curiel, David T.

“…We have previously shown that adenoviral-mediated delivery of an anti-erbB-2 intracellular single-chain antibody (sFv) causes specific cytotoxicy in…”
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Correlation between circulating stromal cell-derived factor 1 levels and CD4+ cell count in human immunodeficiency virus type 1-infected individuals by Derdeyn, C A, Costello, C, Kilby, J M, Sfakianos, G, Saag, M S, Kaslow, R, Bucy, R P

“…Stromal cell-derived factor 1 (SDF-1) is the natural ligand that recognizes CXCR4, which also serves as a coreceptor for some strains of HIV-1. In this study,…”
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Simultaneous quantitation of multiple cytokine mRNAs by RT-PCR utilizing plate based EIA methodology by Hockett, R.D., Janowski, K.M., Bucy, R.P.

“…Cytokines are small protein hormones produced during an immune response that are responsible for mediation and regulation of many aspects of immunity…”
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Avian T cell ontogeny by Cooper, M D, Chen, C L, Bucy, R P, Thompson, C B

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Evaluation of Distinct Blood Lymphocyte Populations in Human Immunodeficiency Virus Type 1—Infected Subjects in the Absence or Presence of Effective Therapy by Derdeyn, Cynthia A., Kilby, J. Michael, Miralles, G. Diego, Li, Li-Fang, Sfakianos, Greg, Saag, Michael S., Hockett, Richard D., Bucy, R. Pat

“…Virus reservoirs can persist in human immunodeficiency virus type 1 (HIV-1)—infected subjects despite effective plasma virus suppression. To compare viral…”
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Persistence of episomal HIV-1 infection intermediates in patients on highly active anti-retroviral therapy by Stevenson, Mario, Sharkey, Mark E, Teo, Ian, Greenough, Thomas, Sharova, Natalia, Luzuriaga, Katherine, Sullivan, John L, Bucy, R. Pat, Kostrikis, Leondios G, Haase, Ashley, Veryard, Claire, Davaro, Raul E, Cheeseman, Sarah H, Daly, Jennifer S, Bova, Carol, Ellison, Richard T, Mady, Brian, Lai, Kwan Kew, Moyle, Graeme, Nelson, Mark, Gazzard, Brian, Shaunak, Sunil

“…Treatment of HIV-1-infected individuals with a combination of anti-retroviral agents results in sustained suppression of HIV-1 replication, as evidenced by a…”
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Analysis of the first two waves of thymus homing stem cells and their T cell progeny in chick-quail chimeras by COLTEY, M, BUCY, R. P, CHEN, C. H, CIHAK, J, LÖSCH, U, CHAR, D, LE DOUARIN, N. M, COOPER, M. D

“…Chick-quail chimeras were used to study precursor/progeny relationships of hemopoietic stem cells (SC) that enter the embryonic thymus in waves to give rise…”
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