Search Results - "BUCKSTEIN, Rena"

How I treat iron overload in adult myelodysplastic syndrome by Leitch, Heather A, Buckstein, Rena J

“…While clinical benefits of iron chelation therapy (ICT) in red blood cell transfusion dependent (RBC TD) hereditary anemias such as beta-thalassemia major are…”
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Integrating patient-centered factors in the risk assessment of MDS by Buckstein, Rena J

“…Myelodysplastic syndromes are clonal myeloid neoplasms that primarily present in older adults. Although leukemia develops in approximately 25% to 30% of…”
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Luspatercept in Patients with Lower-Risk Myelodysplastic Syndromes by Fenaux, Pierre, Platzbecker, Uwe, Mufti, Ghulam J, Garcia-Manero, Guillermo, Buckstein, Rena, Santini, Valeria, Díez-Campelo, María, Finelli, Carlo, Cazzola, Mario, Ilhan, Osman, Sekeres, Mikkael A, Falantes, José F, Arrizabalaga, Beatriz, Salvi, Flavia, Giai, Valentina, Vyas, Paresh, Bowen, David, Selleslag, Dominik, DeZern, Amy E, Jurcic, Joseph G, Germing, Ulrich, Götze, Katharina S, Quesnel, Bruno, Beyne-Rauzy, Odile, Cluzeau, Thomas, Voso, Maria-Teresa, Mazure, Dominiek, Vellenga, Edo, Greenberg, Peter L, Hellström-Lindberg, Eva, Zeidan, Amer M, Adès, Lionel, Verma, Amit, Savona, Michael R, Laadem, Abderrahmane, Benzohra, Aziz, Zhang, Jennie, Rampersad, Anita, Dunshee, Diana R, Linde, Peter G, Sherman, Matthew L, Komrokji, Rami S, List, Alan F

“…Luspatercept is a fusion protein aimed at binding TGF-β family members and reducing SMAD2 and SMAD3 signaling in patients with myelodysplasia with ring…”
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Multicenter, Randomized, Open-Label, Phase III Trial of Decitabine Versus Patient Choice, With Physician Advice, of Either Supportive Care or Low-Dose Cytarabine for the Treatment of Older Patients With Newly Diagnosed Acute Myeloid Leukemia by KANTARJIAN, Hagop M, THOMAS, Xavier G, KUO, Ching-Yuan, ORIOL, Albert, RAVANDI, Farhad, FADERL, Stefan, DELAUNAY, Jacques, LYSAK, Daniel, MINDEN, Mark, ARTHUR, Christopher, DMOSZYNSKA, Anna, WIERZBOWSKA, Agnieszka, MAZUR, Grzegorz, MAYER, Jiri, GAU, Jyh-Pyng, CHOU, Wen-Chien, BUCKSTEIN, Rena, CERMAK, Jaroslav

“…This multicenter, randomized, open-label, phase III trial compared the efficacy and safety of decitabine with treatment choice (TC) in older patients with…”
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Randomized comparison of gemcitabine, dexamethasone, and cisplatin versus dexamethasone, cytarabine, and cisplatin chemotherapy before autologous stem-cell transplantation for relapsed and refractory aggressive lymphomas: NCIC-CTG LY.12 by Crump, Michael, Kuruvilla, John, Couban, Stephen, MacDonald, David A, Kukreti, Vishal, Kouroukis, C Tom, Rubinger, Morel, Buckstein, Rena, Imrie, Kevin R, Federico, Massimo, Di Renzo, Nicola, Howson-Jan, Kang, Baetz, Tara, Kaizer, Leonard, Voralia, Michael, Olney, Harold J, Turner, A Robert, Sussman, Jonathan, Hay, Annette E, Djurfeldt, Marina S, Meyer, Ralph M, Chen, Bingshu E, Shepherd, Lois E

“…For patients with relapsed or refractory aggressive lymphoma, we hypothesized that gemcitabine-based therapy before autologous stem-cell transplantation (ASCT)…”
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Identification of miR-145 and miR-146a as mediators of the 5q- syndrome phenotype by Kuchenbauer, Florian, Lam, Wan, Hogge, Donna, Humphries, R Keith, Marra, Marco, Morin, Ryan, Wells, Richard A, Buckstein, Rena, Hirst, Martin, Starczynowski, Daniel T, Sung, Sandy, Muranyi, Andrew, Karsan, Aly, Argiropoulos, Bob

“…For myelodysplastic syndromes caused by deletion of chromosome 5q, Daniel Starczynowski et al . provide evidence that decreased expression of two miRNAs in…”
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Predictors of intensive care unit admission in patients with hematologic malignancy by Vijenthira, Abi, Chiu, Nicholas, Jacobson, Daniel, Freedman, Zoey, Cheung, Matthew C., Goddard, Shannon, Fowler, Robert, Buckstein, Rena

“…Limited data exist on predictors of intensive care unit (ICU) admission in patients with hematologic malignancy. The objective of this study was to identify…”
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Tumor-associated macrophages predict inferior outcomes in classic Hodgkin lymphoma: a correlative study from the E2496 Intergroup trial by Tan, King L., Scott, David W., Hong, Fangxin, Kahl, Brad S., Fisher, Richard I., Bartlett, Nancy L., Advani, Ranjana H., Buckstein, Rena, Rimsza, Lisa M., Connors, Joseph M., Steidl, Christian, Gordon, Leo I., Horning, Sandra J., Gascoyne, Randy D.

“…Increased tumor-associated macrophages (TAMs) are reported to be associated with poor prognosis in classic Hodgkin lymphoma (CHL). We investigated the…”
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Previously unreported WRAP53 gene variants in a patient with dyskeratosis congenita by Brailovski, Eugene, Tsui, Hubert, Chen, Yi-Bin, Velsher, Lea, Liu, Jiajia, Buckstein, Rena

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Multicenter Study of Decitabine Administered Daily for 5 Days Every 4 Weeks to Adults With Myelodysplastic Syndromes: The Alternative Dosing for Outpatient Treatment (ADOPT) Trial by STEENSMA, David P, BAER, Maria R, KANTARJIAN, Hagop, SLACK, James L, BUCKSTEIN, Rena, GODLEY, Lucy A, GARCIA-MANERO, Guillermo, ALBITAR, Maher, LARSEN, Julie S, ARORA, Sujata, CULLEN, Michael T

“…Decitabine, a DNA-targeted hypomethylating agent, is approved by the United States Food and Drug Administration for treatment of patients with myelodysplastic…”
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High transferrin saturation predicts inferior clinical outcomes in patients with myelodysplastic syndromes by Teichman, Jennifer, Geddes, Michelle, Zhu, Nancy, Keating, Mary-Margaret, Sabloff, Mitchell, Christou, Grace, Leber, Brian, Khalaf, Dina, St-Hilaire, Eve, Finn, Nicholas, Shamy, April, Yee, Karen W L, Storring, John M, Nevill, Thomas J, Delage, Robert, Elemary, Mohamed, Banerji, Versha, Houston, Brett, Mozessohn, Lee, Chodirker, Lisa, Zhang, Liying, Siddiqui, Mohammed, Parmentier, Anne, Leitch, Heather A, Buckstein, Rena J

“…Iron overload (IO) reflected by elevated ferritin is associated with increased mortality in myelodysplastic syndromes (MDS), however, ferritin is an imperfect…”
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Developing Organizational Requirements to Standardize Delivery and Improve Quality of Acute Leukemia Care in Ontario by Verville, Leslie, McKay, Cassandra, Kouroukis, Tom, Apostolovski, Suzanna, Sabloff, Mitchell, Buckstein, Rena, Kennedy, Kardi, Yee, Karen, Eakins, Amanda, Bredeson, Christopher

“…Acute leukemia is a rapidly progressive cancer of the blood and bone marrow that requires a high degree of complex, specialized, resource-intensive clinical…”
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Prospective international validation of the Quality of Life in Myelodysplasia Scale (QUALMS) by Abel, Gregory A, Efficace, Fabio, Buckstein, Rena J, Tinsley, Sara, Jurcic, Joseph G, Martins, Yolanda, Steensma, David P, Watts, Corey D, Raza, Azra, Lee, Stephanie J, List, Alan F, Klaassen, Robert J

“…Disease-specific measures of quality of life can improve assessment of disease-related symptoms and psychosocial sequelae. We report on the development and…”
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Predictors of delay in diagnosis and treatment in diffuse large B‐cell lymphoma and impact on survival by Nikonova, Anna, Guirguis, Hany R., Buckstein, Rena, Cheung, Matthew C.

“…Summary There is a paucity of data on the impact of diagnostic and treatment delays on outcomes in haematological malignancies, particularly in patients with…”
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Comorbid and inflammatory characteristics of genetic subtypes of clonal hematopoiesis by Cook, Elina K., Izukawa, Terumi, Young, Sherylan, Rosen, Gili, Jamali, Mina, Zhang, Liying, Johnson, Dylan, Bain, Eva, Hilland, Jamie, Ferrone, Christina K., Buckstein, Jonah, Francis, Janika, Momtaz, Bushra, McNaughton, Amy J.M., Liu, Xudong, Snetsinger, Brooke, Buckstein, Rena, Rauh, Michael J.

“…•CH may be associated with broader ill health (worse performance status, increased and potentially novel comorbidities).•Serum interleukin-6 is elevated in…”
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P581: A MARKOV DECISION ANALYSIS OF AZACITIDINE AND VENETOCLAX VERSUS INDUCTION CHEMOTHERAPY FOR THE TREATMENT OF MEDICALLY-FIT PATIENTS WITH ACUTE MYELOID LEUKEMIA by Ravindran, Mithunan, Teichman, Jennifer, Mozessohn, Lee, Cheung, Matthew, Buckstein, Rena

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Revised 15-item MDS-specific frailty scale maintains prognostic potential by Wan, Bo A., Nazha, Aziz, Starkman, Rebecca, Alibhai, Shabbir, Wells, Richard. A., Geddes, Michelle, Zhu, Nancy, Keating, Mary-Margaret, Leber, Brian, Chodirker, Lisa, Sabloff, Mitchell, Christou, Grace, Leitch, Heather A., St-Hilaire, Eve, Finn, Nicholas, Shamy, April, Yee, Karen W. L., Storring, John, Nevill, Thomas J., Delage, Robert, Elemary, Mohamed, Banerji, Versha, Parmentier, Anne, Siddiqui, Mohammad, Kirubananthaan, Aksharh, Mamedov, Alexandre, Zhang, Liying, Buckstein, Rena

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The impact of oral hypoglycemics and statins on outcomes in myelodysplastic syndromes by Brailovski, Eugene, Li, Qing, Liu, Ning, Leber, Brian, Khalaf, Dina, Sabloff, Mitchell, Christou, Grace, Yee, Karen, Chodirker, Lisa, Parmentier, Anne, Siddiqui, Mohammed, Mamedov, Alexandre, Zhang, Liying, Liu, Ying, Earle, Craig C., Cheung, Matthew C., Mittmann, Nicole, Buckstein, Rena J., Mozessohn, Lee

“…Observational studies suggest an anti-neoplastic effect associated with statins, metformin, and dipeptidyl peptidase-4 inhibitors (DPP4i), while sulfonylureas…”
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Autologous and Allogeneic Stem-Cell Transplantation for Transformed Follicular Lymphoma: A Report of the Canadian Blood and Marrow Transplant Group by VILLA, Diego, CRUMP, Michael, RUBINGER, Morel, FOLEY, Ronan, XENOCOSTAS, Anargyros, SABLOFF, Mitchell, MUCCILLI, Alexandra, CHUA, Neil, COUTURE, Felix, LAROUCHE, Jean-François, COHEN, Sandra, CONNORS, Joseph M, PANZARELLA, Tony, AMBLER, Kimberley, AL-TOURAH, Abdulwahab, RAMADAN, Khaled M, KURUVILLA, John, SAVAGE, Kerry J, TOZE, Cynthia L, STEWART, Douglas A, MACDONALD, David A, BUCKSTEIN, Rena, LEE, Christina, ALZAHRANI, Mohsen

“…To determine whether autologous (auto) or allogeneic (allo) stem-cell transplantation (SCT) improves outcome in patients with transformed follicular lymphoma…”
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Intensive versus less-intensive antileukemic therapy in older adults with acute myeloid leukemia: A systematic review by Chang, Yaping, Guyatt, Gordon H, Teich, Trevor, Dawdy, Jamie L, Shahid, Shaneela, Altman, Jessica K, Stone, Richard M, Sekeres, Mikkael A, Mukherjee, Sudipto, LeBlanc, Thomas W, Abel, Gregory A, Hourigan, Christopher S, Litzow, Mark R, Michaelis, Laura C, Alibhai, Shabbir M H, Desai, Pinkal, Buckstein, Rena, MacEachern, Janet, Brignardello-Petersen, Romina

“…To compare the effectiveness and safety of intensive antileukemic therapy to less-intensive therapy in older adults with acute myeloid leukemia (AML) and…”
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