Search Results - "BUCKINGHAM, ROBIN E."

Rosiglitazone, a Peroxisome Proliferator-Activated Receptor-γ, Inhibits the Jun NH2-Terminal Kinase/Activating Protein 1 Pathway and Protects the Heart From Ischemia/Reperfusion Injury by Khandoudi, Nassirah, Delerive, Philippe, Berrebi-Bertrand, Isabelle, Buckingham, Robin E., Staels, Bart, Bril, Antoine

“…Rosiglitazone, a Peroxisome Proliferator-Activated Receptor-γ, Inhibits the Jun NH 2 -Terminal Kinase/Activating Protein 1 Pathway and Protects the Heart From…”
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Thiazolidinedione Treatment Normalizes Insulin Resistance and Ischemic Injury in the Zucker Fatty Rat Heart by SIDELL, Robert J, COLE, Mark A, DRAPER, Nicholas J, DESROIS, Martine, BUCKINGHAM, Robin E, CLARKE, Kieran

“…Thiazolidinedione Treatment Normalizes Insulin Resistance and Ischemic Injury in the Zucker Fatty Rat Heart Robert J. Sidell 1 , Mark A. Cole 1 , Nicholas J…”
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Effects of single and chronic intracerebroventricular administration of the orexins on feeding in the rat by Haynes, Andrea C, Jackson, Brian, Overend, Phil, Buckingham, Robin E, Wilson, Shelagh, Tadayyon, Mohammad, Arch, Jonathan R.S

“…Two novel hypothalamic neuropeptides, orexin-A and -B, are suggested to regulate feeding. A single intracerebroventricular injection of orexin-A (23.4 nmol),…”
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Thiazolidinediones and their fluid-related adverse effects : Facts, fiction and putative management strategies by KARALLIEDDE, Janaka, BUCKINGHAM, Robin E

“…Thiazolidinediones (TZDs) or glitazones are agents that are widely used for the treatment of type 2 diabetes mellitus. These drugs have a multitude of…”
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Abnormal cardiac and skeletal muscle energy metabolism in patients with type 2 diabetes by SCHEUERMANN-FREESTONE, Michaela, MADSEN, Per L, MANNERS, David, BLAMIRE, Andrew M, BUCKINGHAM, Robin E, STYLES, Peter, RADDA, George K, NEUBAUER, Stefan, CLARKE, Kieran

“…It is well known that patients with type 2 diabetes have increased risk of cardiovascular disease, but it is not known whether they have underlying…”
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Mechanical stretch induces monocyte chemoattractant activity via an NF-κB-dependent monocyte chemoattractant protein-1-mediated pathway in human mesangial cells : Inhibition by rosiglitazone by GRUDEN, Gabriella, SETTI, Giorgia, HAYWARD, Anthea, SUGDEN, David, DUGGAN, Sara, BURT, Davina, BUCKINGHAM, Robin E, GNUDI, Luigi, VIBERTI, Giancarlo

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β-cell mass dynamics in Zucker diabetic fatty rats rosiglitazone prevents the rise in net cell death by FINEGOOD, Diane T, DAWN MCARTHUR, M, KOJWANG, David, THOMAS, Marion J, TOPP, Brian G, LEONARD, Thomas, BUCKINGHAM, Robin E

“…The evolution of diabetes in the male leptin receptor-deficient (fa/fa) Zucker diabetic fatty (ZDF) rat is associated with disruption of normal islet…”
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Orexins and Orexin Receptors: A Family of Hypothalamic Neuropeptides and G Protein-Coupled Receptors that Regulate Feeding Behavior by Sakurai, Takeshi, Amemiya, Akira, Ishii, Makoto, Matsuzaki, Ichiyo, Chemelli, Richard M, Tanaka, Hirokazu, Williams, S.Clay, Richardson, James A, Kozlowski, Gerald P, Wilson, Shelagh, Arch, Jonathan R.S, Buckingham, Robin E, Haynes, Andrea C, Carr, Steven A, Annan, Roland S, McNulty, Dean E, Liu, Wu-Schyong, Terrett, Jonathan A, Elshourbagy, Nabil A, Bergsma, Derk J, Yanagisawa, Masashi

“…The hypothalamus plays a central role in the integrated control of feeding and energy homeostasis. We have identified two novel neuropeptides, both derived…”
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In vivo myocardial protection from ischemia/reperfusion injury by the peroxisome proliferator-activated receptor-γ agonist rosiglitazone by YUE, Tian-Li, JUN CHEN, HART, Timothy K, BUCKINGHAM, Robin E, OHLSTEIN, Eliot H, WEIKE BAO, NARAYANAN, Padma K, BRIL, Antoine, WEN JIANG, LYSKO, Paul G, GU, Juan-Li, BOYCE, Rogely, ZIMMERMAN, Dawn M

“…Diabetes is associated with increased risk of mortality as a consequence of acute myocardial infarction. This study determined whether rosiglitazone (ROSI)…”
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The thiazolidinedione rosiglitazone (BRL-49653) lowers blood pressure and protects against impairment of endothelial function in Zucker fatty rats by WALKER, A. B, CHATTINGTON, P. D, BUCKINGHAM, R. E, WILLIAMS, G

“…The thiazolidinedione rosiglitazone (BRL-49653) lowers blood pressure and protects against impairment of endothelial function in Zucker fatty rats. A B Walker…”
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Differential distribution of orexin-A and orexin-B immunoreactivity in the rat brain and spinal cord by Cutler, David J, Morris, Richard, Sheridhar, Vimal, Wattam, Trevor A.K, Holmes, Stephen, Patel, Sara, Arch, Jonathan R.S, Wilson, Shelagh, Buckingham, Robin E, Evans, Martyn L, Leslie, Ron A, Williams, Gareth

“…The orexins are recently identified appetite-stimulating hypothalamic peptides. We used immunohistochemistry to map orexin-A and orexin-B immunoreactivity in…”
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Differential vasoactive effects of the insulin sensitizers rosiglitazone (BRL 49653) and troglitazone on human small arteries in vitro by WALKER, A. B, NADERALI, E. K, CHATTINGTON, P. D, BUCKINGHAM, R. E, WILLIAMS, G

“…Differential vasoactive effects of the insulin sensitizers rosiglitazone (BRL 49653) and troglitazone on human small arteries in vitro. A B Walker , E K…”
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Central Exendin-4 Infusion Reduces Body Weight without Altering Plasma Leptin in ( ) Zucker Rats by Al‐Barazanji, Kamal A., Arch, Jonathan R. S., Buckingham, Robin E., Tadayyon, Mohammad

“…Objective: To investigate whether chronic administration of the long‐acting glucagon‐like peptide‐1 receptor agonist exendin‐4 can elicit sustained reductions…”
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Characterisation of the neuropeptide Y receptor that mediates feeding in the rat: a role for the Y5 receptor? by Haynes, Andrea C, Arch, Jonathan R.S, Wilson, Shelagh, Steven Mc Clue, Buckingham, Robin E

“…Food intake was measured in freely fed rats following intracerebroventricular administration of neuropeptide Y (NPY) and several of its analogues and…”
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The haemodynamic profile of cromakalim in the cat by Clapham, J C, Buckingham, R E

“…The haemodynamic profile of the novel antihypertensive agent, cromakalim (BRL 34915), has been studied in conscious and anaesthetised cats. Given orally (0.03…”
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β-Cell Mass Dynamics in Zucker Diabetic Fatty Rats by Finegood, Diane T., McArthur, M. Dawn, Kojwang, David, Thomas, Marion J., Topp, Brian G., Leonard, Thomas, Buckingham, Robin E.

“…β-Cell Mass Dynamics in Zucker Diabetic Fatty Rats Rosiglitazone Prevents the Rise in Net Cell Death Diane T. Finegood 1 , M. Dawn McArthur 1 , David Kojwang 1…”
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Inhibition by glibenclamide of the vasorelaxant action of cromakalim in the rat by Buckingham, Robin E., Hamilton, Thomas C., Howlett, David R., Mootoo, Sheila, Wilson, Campbell

“…1 In rat isolated thoracic aortic rings pre‐contracted with noradrenaline (10−6 m), cromakalim (3 × 10−7‐3 × 10−5 m) produced concentration‐related relaxation…”
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Down-regulation of orexin gene expression by severe obesity in the rats: studies in Zucker fatty and Zucker diabetic fatty rats and effects of rosiglitazone by Cai, Xue J., Lister, Carolyn A., Buckingham, Robin E., Pickavance, Lucy, Wilding, John, Arch, Jonathan R.S., Wilson, Shelagh, Williams, Gareth

“…Orexins (hypocretins) are lateral hypothalamic neuropeptides implicated in regulating feeding and the sleep–wake cycle. To study their possible relevance to…”
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Synthesis and antihypertensive activity of 4-(cyclic amido)-2H-1-benzopyrans by Ashwood, Valerie A, Buckingham, Robin E, Cassidy, Frederick, Evans, John M, Faruk, Erol A, Hamilton, Thomas C, Nash, David J, Stemp, Geoffrey, Willcocks, Kenneth

“…The synthesis and antihypertensive activity of a series of novel 4-(cyclic amido)-2H-1-benzopyran-3-ols, administered orally to conscious spontaneously…”
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Differences between the Vasorelaxant Activity of Adenosine-receptor Agonists on Guinea-pig Isolated Aorta Precontracted with Noradrenaline or Phenylephrine by FORD, WILLIAM R., MADDOCK, HELEN L., BUCKINGHAM, ROBIN E., BROADLEY, KENNETH J.

“…The relaxant effect of adenosine and 5′‐(N‐ethylcarboxamido)adenosine (NECA) against α‐adrenoceptor‐mediated contractile tone in guinea‐pig isolated aortic…”
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