Search Results - "BUCKINGHAM, Bruce A"
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Optimizing Hybrid Closed-Loop Therapy in Adolescents and Emerging Adults Using the MiniMed 670G System
Published in Diabetes care (01-04-2018)“…The MiniMed 670G System is the first commercial hybrid closed-loop (HCL) system for management of type 1 diabetes. Using data from adolescent and young adult…”
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Day and Night Closed-Loop Control Using the Integrated Medtronic Hybrid Closed-Loop System in Type 1 Diabetes at Diabetes Camp
Published in Diabetes care (01-07-2015)“…To evaluate the feasibility and efficacy of a fully integrated hybrid closed-loop (HCL) system (Medtronic MiniMed Inc., Northridge, CA), in day and night…”
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Successful At-Home Use of the Tandem Control-IQ Artificial Pancreas System in Young Children During a Randomized Controlled Trial
Published in Diabetes technology & therapeutics (01-04-2019)“…Hybrid closed-loop (HCL) artificial pancreas (AP) systems are now moving from research settings to widespread clinical use. In this study, the inControl…”
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Predictive Low-Glucose Insulin Suspension Reduces Duration of Nocturnal Hypoglycemia in Children Without Increasing Ketosis
Published in Diabetes care (01-07-2015)“…Nocturnal hypoglycemia can cause seizures and is a major impediment to tight glycemic control, especially in young children with type 1 diabetes. We conducted…”
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A Randomized Trial of a Home System to Reduce Nocturnal Hypoglycemia in Type 1 Diabetes
Published in Diabetes care (01-07-2014)“…Overnight hypoglycemia occurs frequently in individuals with type 1 diabetes and can result in loss of consciousness, seizure, or even death. We conducted an…”
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Closed loop control in adolescents and children during winter sports: Use of the Tandem Control‐IQ AP system
Published in Pediatric diabetes (01-09-2019)“…Objective Artificial pancreas (AP) systems have been shown to improve glycemic control throughout the day and night in adults, adolescents, and children…”
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Sensitive detection of multiple islet autoantibodies in type 1 diabetes using small sample volumes by agglutination-PCR
Published in PloS one (13-11-2020)“…Islet autoantibodies are predominantly measured by radioassay to facilitate risk assessment and diagnosis of type 1 diabetes. However, the reliance on…”
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Evaluation of a Predictive Low-Glucose Management System In-Clinic
Published in Diabetes technology & therapeutics (01-05-2017)“…Predictions based on continuous glucose monitoring (CGM) data are the basis for automatic suspension and resumption of insulin delivery by a predictive…”
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Feasibility of Detecting Neuropsychologic and Neuroanatomic Effects of Type 1 Diabetes in Young Children
Published in Diabetes care (01-07-2011)“…OBJECTIVE: To determine if frequent exposures to hypoglycemia and hyperglycemia during early childhood lead to neurocognitive deficits and changes in brain…”
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Reduction in duration of hypoglycemia by automatic suspension of insulin delivery: the in-clinic ASPIRE study
Published in Diabetes technology & therapeutics (01-03-2012)“…The efficacy of automatic suspension of insulin delivery in induced hypoglycemia among subjects with type 1 diabetes was evaluated. In this randomized…”
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Optimal sampling intervals to assess long-term glycemic control using continuous glucose monitoring
Published in Diabetes technology & therapeutics (01-03-2011)“…The optimal duration and frequency of short-term continuous glucose monitoring (CGM) to reflect long-term glycemia have not been determined. The Juvenile…”
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Continuous Glucose Monitoring Enables the Detection of Losses in Infusion Set Actuation (LISAs)
Published in Sensors (Basel, Switzerland) (15-01-2017)“…Reliable continuous glucose monitoring (CGM) enables a variety of advanced technology for the treatment of type 1 diabetes. In addition to artificial pancreas…”
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The dawn of automated insulin delivery: A new clinical framework to conceptualize insulin administration
Published in Pediatric diabetes (01-02-2018)Get full text
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Ultra‐Fast Insulin–Pramlintide Co‐Formulation for Improved Glucose Management in Diabetic Rats
Published in Advanced science (01-11-2021)“…Dual‐hormone replacement therapy with insulin and amylin in patients with type 1 diabetes has the potential to improve glucose management. Unfortunately,…”
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Two-Center Randomized Controlled Feasibility Trial of Insulin Pump Therapy in Young Children With Diabetes
Published in Diabetes care (2005)“…OBJECTIVE:--Our goals were to determine if continuous subcutaneous insulin infusion (CSII), compared with those continuing multiple daily injections (MDIs),…”
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Predictive hyperglycemia and hypoglycemia minimization: In‐home double‐blind randomized controlled evaluation in children and young adolescents
Published in Pediatric diabetes (01-05-2018)“…Objective The primary objective of this trial was to evaluate the feasibility, safety, and efficacy of a predictive hyperglycemia and hypoglycemia minimization…”
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Safety of a Hybrid Closed-Loop Insulin Delivery System in Patients With Type 1 Diabetes
Published in JAMA : the journal of the American Medical Association (04-10-2016)Get full text
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Automation of a multiplex agglutination-PCR (ADAP) type 1 diabetes (T1D) assay for the rapid analysis of islet autoantibodies
Published in SLAS technology (01-02-2022)“…Screening for islet autoantibody markers to identify individuals who are at high risk for developing type 1 diabetes (T1D), often years in advance of clinical…”
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Modular artificial beta-cell system: a prototype for clinical research
Published in Journal of diabetes science and technology (01-09-2008)“…The quest toward an artificial beta-cell has been accelerating, propelled by recent technological advances in subcutaneous glucose sensors and insulin pumps…”
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Full closed loop open‐source algorithm performance comparison in pigs with diabetes
Published in Clinical and translational medicine (01-04-2021)“…Understanding how automated insulin delivery (AID) algorithm features impact glucose control under full closed loop delivery represents a critical step toward…”
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