Search Results - "BUCK, DAVID C"
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Distinct regulation of dopamine D2S and D2L autoreceptor signaling by calcium
Published in eLife (26-08-2015)“…D2 autoreceptors regulate dopamine release throughout the brain. Two isoforms of the D2 receptor, D2S and D2L, are expressed in midbrain dopamine neurons…”
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Role for Rab10 in Methamphetamine-Induced Behavior
Published in PloS one (20-08-2015)“…Lipid rafts are specialized, cholesterol-rich membrane compartments that help to organize transmembrane signaling by restricting or promoting interactions with…”
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Altered Endothelial Nitric Oxide Synthase Targeting and Conformation and Caveolin-1 Expression in the Diabetic Kidney
Published in Diabetes (New York, N.Y.) (01-06-2006)“…Altered Endothelial Nitric Oxide Synthase Targeting and Conformation and Caveolin-1 Expression in the Diabetic Kidney Radko Komers 1 2 3 , William E. Schutzer…”
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Arrestin recruitment to dopamine D2 receptor mediates locomotion but not incentive motivation
Published in Molecular psychiatry (01-09-2020)“…The dopamine (DA) D2 receptor (D2R) is an important target for the treatment of neuropsychiatric disorders such as schizophrenia and Parkinson’s disease…”
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Novel interaction of the dopamine D2 receptor and the Ca2+ binding protein S100B: role in D2 receptor function
Published in Molecular pharmacology (01-08-2008)“…S100B is a calcium-binding protein with both extracellular and intracellular regulatory activities in the mammalian brain. We have identified a novel…”
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What is the cost of non-response to cardiac resynchronization therapy? Hospitalizations and healthcare utilization in the CRT-D population
Published in Journal of interventional cardiac electrophysiology (01-11-2016)“…Background Cardiac resynchronization therapy (CRT) is an effective treatment for heart failure (HF) with left ventricular systolic dysfunction and prolonged…”
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Signaling-Biased and Constitutively Active Dopamine D2 Receptor Variant
Published in ACS chemical neuroscience (02-06-2021)“…A dopamine D2 receptor mutation was recently identified in a family with a novel hyperkinetic movement disorder. Compared to the wild type D2 receptor, the…”
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Dopamine D2 receptor stimulation of mitogen‐activated protein kinases mediated by cell type‐dependent transactivation of receptor tyrosine kinases
Published in Journal of neurochemistry (01-05-2005)“…Dopamine D2 receptor activation of extracellular signal‐regulated kinases (ERKs) in non‐neuronal human embryonic kidney 293 cells was dependent on…”
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Bone Formation with Use of rhBMP-2 (Recombinant Human Bone Morphogenetic Protein-2)
Published in Journal of bone and joint surgery. American volume (01-12-1997)“…We examined the effect of rhBMP-2 (recombinant human bone morphogenetic protein-2), delivered in a porous poly(DL-lactic acid) implant, on bone formation in a…”
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Timeline of tibial tunnel expansion after single-incision hamstring anterior cruciate ligament reconstruction
Published in Arthroscopy (2004)“…Purpose: The purpose of this study was to determine the time frame for tibial tunnel expansion in patients undergoing anterior cruciate ligament (ACL)…”
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Modeling and mutational analysis of a putative sodium-binding pocket on the dopamine D2 receptor
Published in Molecular pharmacology (01-08-2001)“…A homology model of the dopamine D2 receptor was constructed based on the crystal structure of rhodopsin. A putative sodium-binding pocket identified in an…”
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Evidence That Calmodulin Binding to the Dopamine D2 Receptor Enhances Receptor Signaling
Published in Journal of receptors and signal transduction (2007)“…The Ca2+ sensor calmodulin (CaM) regulates numerous proteins involved in G protein-coupled receptor (GPCR) signaling. CaM binds directly to some GPCRs,…”
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Lipoic acid downmodulates CD4 from human T lymphocytes by dissociation of p56(Lck)
Published in Biochemical and biophysical research communications (09-06-2006)“…Lipoic acid is an antioxidant that suppresses and treats a model of multiple sclerosis, experimental autoimmune encephalomyelitis. We now demonstrate that…”
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Open anterior repair without routine capsulorraphy for traumatic anterior shoulder instability in a community setting
Published in Orthopedics (Thorofare, N.J.) (01-04-2008)“…Anterior shoulder instability repairs often are performed but rarely reported in community practices. This study assessed outcomes after open anterior repairs…”
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Recombinant human bone morphogenetic protein-2 and collagen for bone regeneration
Published in Journal of biomedical materials research (1998)“…The study reported describes a combination of recombinant human bone morphogenetic protein‐2 (rhBMP‐2) and collagen (C) to regenerate bone. Unilateral…”
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Journal Article Conference Proceeding -
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Comparison of Porous Bone Mineral and Biologically Active Glass in Critical‐Sized Defects
Published in Journal of periodontology (1970) (01-11-1997)“…Several materials have been proposed as therapies to augment alveolar bone and to promote periodontal regeneration. However, there are an insufficient number…”
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Tunable Photochemical/Redox Properties of (Phenylthio)ncorannulenes: Application to a Photovoltaic Device
Published in Journal of the Brazilian Chemical Society (01-10-2016)“…The additive substituent effect of phenylmercapto derivatives of corannulene are investigated by spectroscopic, electrochemical, and computational techniques…”
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Normalizing dopamine D2 receptor-mediated responses in D2 null mutant mice by virus-mediated receptor restoration: Comparing D2L and D2S
Published in Neuroscience (17-09-2013)“…Highlights • We compare the function of splice variants of the dopamine D2 receptor D2s and D2L. • We used virus-mediated expression of the receptors in D2…”
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Evidence That Calmodulin Binding to the Dopamine D 2 Receptor Enhances Receptor Signaling
Published in Journal of receptors and signal transduction (01-01-2007)Get full text
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