Search Results - "BUCK, Amy H"

Small RNAs and extracellular vesicles: New mechanisms of cross-species communication and innovative tools for disease control by Cai, Qiang, He, Baoye, Weiberg, Arne, Buck, Amy H, Jin, Hailing

“…State Key Laboratory of Hybrid Rice, College of Life Sciences, Wuhan University, Wuhan, China Affiliation: Department of Microbiology and Plant Pathology,…”
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Exosomes and Other Extracellular Vesicles: The New Communicators in Parasite Infections by Coakley, Gillian, Maizels, Rick M, Buck, Amy H

“…Extracellular vesicles (EVs) have emerged as a ubiquitous mechanism for transferring information between cells and organisms across all three kingdoms of life…”
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Small RNA Profiling in Dengue Virus 2-Infected Aedes Mosquito Cells Reveals Viral piRNAs and Novel Host miRNAs by Miesen, Pascal, Ivens, Alasdair, Buck, Amy H, van Rij, Ronald P

“…In Aedes mosquitoes, infections with arthropod-borne viruses (arboviruses) trigger or modulate the expression of various classes of viral and host-derived…”
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Exosomes secreted by nematode parasites transfer small RNAs to mammalian cells and modulate innate immunity by Buck, Amy H., Coakley, Gillian, Simbari, Fabio, McSorley, Henry J., Quintana, Juan F., Le Bihan, Thierry, Kumar, Sujai, Abreu-Goodger, Cei, Lear, Marissa, Harcus, Yvonne, Ceroni, Alessandro, Babayan, Simon A., Blaxter, Mark, Ivens, Alasdair, Maizels, Rick M.

“…In mammalian systems RNA can move between cells via vesicles. Here we demonstrate that the gastrointestinal nematode Heligmosomoides polygyrus , which infects…”
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Extracellular Vesicles from a Helminth Parasite Suppress Macrophage Activation and Constitute an Effective Vaccine for Protective Immunity by Coakley, Gillian, McCaskill, Jana L., Borger, Jessica G., Simbari, Fabio, Robertson, Elaine, Millar, Marissa, Harcus, Yvonne, McSorley, Henry J., Maizels, Rick M., Buck, Amy H.

“…Recent studies have demonstrated that many parasites release extracellular vesicles (EVs), yet little is known about the specific interactions of EVs with…”
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The Discovery, Distribution, and Evolution of Viruses Associated with Drosophila melanogaster by Webster, Claire L, Waldron, Fergal M, Robertson, Shaun, Crowson, Daisy, Ferrari, Giada, Quintana, Juan F, Brouqui, Jean-Michel, Bayne, Elizabeth H, Longdon, Ben, Buck, Amy H, Lazzaro, Brian P, Akorli, Jewelna, Haddrill, Penelope R, Obbard, Darren J

“…Drosophila melanogaster is a valuable invertebrate model for viral infection and antiviral immunity, and is a focus for studies of insect-virus coevolution…”
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Functional diversification of Argonautes in nematodes: an expanding universe by Buck, Amy H, Blaxter, Mark

“…In the last decade, many diverse RNAi (RNA interference) pathways have been discovered that mediate gene silencing at epigenetic, transcriptional and…”
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RNA-RNA interactions between respiratory syncytial virus and miR-26 and miR-27 are associated with regulation of cell cycle and antiviral immunity by Ressel, Sarah, Kumar, Sujai, Bermúdez-Barrientos, Jose Roberto, Gordon, Katrina, Lane, Julia, Wu, Jin, Abreu-Goodger, Cei, Schwarze, Jürgen, Buck, Amy H

“…microRNAs (miRNAs) regulate nearly all physiological processes but our understanding of exactly how they function remains incomplete, particularly in the…”
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Extracellular small RNAs: what, where, why? by Hoy, Anna M, Buck, Amy H

“…miRNAs (microRNAs) are a class of small RNA that regulate gene expression by binding to mRNAs and modulating the precise amount of proteins that get expressed…”
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The evolution of RNAi as a defence against viruses and transposable elements by Obbard, Darren J, Gordon, Karl H.J, Buck, Amy H, Jiggins, Francis M

“…RNA interference (RNAi) is an important defence against viruses and transposable elements (TEs). RNAi not only protects against viruses by degrading viral RNA,…”
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Obstacles and opportunities in the functional analysis of extracellular vesicle RNA - an ISEV position paper by Mateescu, Bogdan, Kowal, Emma J. K., van Balkom, Bas W. M., Bartel, Sabine, Bhattacharyya, Suvendra N., Buzás, Edit I., Buck, Amy H., de Candia, Paola, Chow, Franklin W. N., Das, Saumya, Driedonks, Tom A. P., Fernández-Messina, Lola, Haderk, Franziska, Hill, Andrew F., Jones, Jennifer C., Van Keuren-Jensen, Kendall R., Lai, Charles P., Lässer, Cecilia, di Liegro, Italia, Lunavat, Taral R., Lorenowicz, Magdalena J., Maas, Sybren L. N., Mäger, Imre, Mittelbrunn, Maria, Momma, Stefan, Mukherjee, Kamalika, Nawaz, Muhammad, Pegtel, D. Michiel, Pfaffl, Michael W., Schiffelers, Raymond M., Tahara, Hidetoshi, Théry, Clotilde, Tosar, Juan Pablo, Wauben, Marca H. M., Witwer, Kenneth W., Nolte-'t Hoen, Esther N. M.

“…The release of RNA-containing extracellular vesicles (EV) into the extracellular milieu has been demonstrated in a multitude of different in vitro cell systems…”
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Parasite-derived microRNAs in host serum as novel biomarkers of helminth infection by Hoy, Anna M, Lundie, Rachel J, Ivens, Alasdair, Quintana, Juan F, Nausch, Norman, Forster, Thorsten, Jones, Frances, Kabatereine, Narcis B, Dunne, David W, Mutapi, Francisca, Macdonald, Andrew S, Buck, Amy H

“…MicroRNAs (miRNAs) are a class of short non-coding RNA that play important roles in disease processes in animals and are present in a highly stable cell-free…”
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Murine cytomegalovirus encodes a miR-27 inhibitor disguised as a target by Libri, Valentina, Helwak, Aleksandra, Miesen, Pascal, Santhakumar, Diwakar, Borger, Jessica G, Kudla, Grzegorz, Grey, Finn, Tollervey, David, Buck, Amy H

“…Individual microRNAs (miRNAs) are rapidly down-regulated during conditions of cellular activation and infection, but factors mediating miRNA turnover are…”
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Ancient diversity in host-parasite interaction genes in a model parasitic nematode by Stevens, Lewis, Martínez-Ugalde, Isaac, King, Erna, Wagah, Martin, Absolon, Dominic, Bancroft, Rowan, Gonzalez de la Rosa, Pablo, Hall, Jessica L., Kieninger, Manuela, Kloch, Agnieszka, Pelan, Sarah, Robertson, Elaine, Pedersen, Amy B., Abreu-Goodger, Cei, Buck, Amy H., Blaxter, Mark

“…Host-parasite interactions exert strong selection pressures on the genomes of both host and parasite. These interactions can lead to negative…”
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Disentangling sRNA-Seq data to study RNA communication between species by Bermúdez-Barrientos, José Roberto, Ramírez-Sánchez, Obed, Chow, Franklin Wang-Ngai, Buck, Amy H, Abreu-Goodger, Cei

“…Many organisms exchange small RNAs (sRNAs) during their interactions, that can target or bolster defense strategies in host-pathogen systems. Current sRNA-Seq…”
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Organoids as tools to investigate gastrointestinal nematode development and host interactions by White, Ruby, Blow, Frances, Buck, Amy H, Duque-Correa, María A

“…Gastrointestinal nematodes are a diverse class of pathogens that colonise a quarter of the world's human population and nearly all grazing livestock. These…”
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Post-transcriptional regulation of miR-27 in murine cytomegalovirus infection by Buck, Amy H, Perot, Jonathan, Chisholm, Michael A, Kumar, Diwakar S, Tuddenham, Lee, Cognat, Valérie, Marcinowski, Lisa, Dölken, Lars, Pfeffer, Sébastien

“…In mammals, microRNAs (miRNAs) can play diverse roles in viral infection through their capacity to regulate both host and viral genes. Recent reports have…”
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Broad-Spectrum Inhibition of Respiratory Virus Infection by MicroRNA Mimics Targeting p38 MAPK Signaling by McCaskill, Jana L., Ressel, Sarah, Alber, Andreas, Redford, Jane, Power, Ultan F., Schwarze, Jürgen, Dutia, Bernadette M., Buck, Amy H.

“…The majority of antiviral therapeutics target conserved viral proteins, however, this approach confers selective pressure on the virus and increases the…”
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SID-2 is a conserved extracellular vesicle protein that is not associated with environmental RNAi in parasitic nematodes by Blow, Frances, Jeffrey, Kate, Chow, Franklin Wang-Ngai, Nikonorova, Inna A., Barr, Maureen M., Cook, Atlanta G., Prevo, Bram, Cheerambathur, Dhanya K., Buck, Amy H.

“…In the free-living nematode Caenorhabditis elegans, the transmembrane protein SID-2 imports double-stranded RNA into intestinal cells to trigger systemic RNA…”
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Extracellular Onchocerca-derived small RNAs in host nodules and blood by Quintana, Juan F, Makepeace, Benjamin L, Babayan, Simon A, Ivens, Alasdair, Pfarr, Kenneth M, Blaxter, Mark, Debrah, Alexander, Wanji, Samuel, Ngangyung, Henrietta F, Bah, Germanus S, Tanya, Vincent N, Taylor, David W, Hoerauf, Achim, Buck, Amy H

“…BACKGROUND: microRNAs (miRNAs), a class of short, non-coding RNA can be found in a highly stable, cell-free form in mammalian body fluids. Specific miRNAs are…”
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