Search Results - "BUCHER, Michael"

Cytoskeletal makeup of the synapse: Shaft versus spine by Bucher, Michael, Fanutza, Tomas, Mikhaylova, Marina

“…The ability of neurons to communicate and store information depends on the activity of synapses which can be located on small protrusions (dendritic spines) or…”
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Phage against the Machine: The SIE-ence of Superinfection Exclusion by Bucher, Michael J, Czyż, Daniel M

“…Prophages can alter their bacterial hosts to prevent other phages from infecting the same cell, a mechanism known as superinfection exclusion (SIE). Such…”
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The synergism of cytosolic acidosis and reduced NAD + /NADH ratio is responsible for lactic acidosis-induced vascular smooth muscle cell impairment in sepsis by Terpe, Philipp, Ruhs, Stefanie, Dubourg, Virginie, Bucher, Michael, Gekle, Michael

“…During sepsis, serve vascular dysfunctions lead to life-threatening multiple organ failure, due to vascular smooth muscle cells (VSMC) impairments, resulting…”
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Impact of Unsaturated Fatty Acids on Cytokine-Driven Endothelial Cell Dysfunction by Trommer, Simon, Leimert, Anja, Bucher, Michael, Schumann, Julia

“…Polyunsaturated fatty acids (PUFA) are reported to exert prophylactic and acute therapeutic effects in diseases linked to endothelial dysfunction. In the…”
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SATB2‐LEMD2 interaction links nuclear shape plasticity to regulation of cognition‐related genes by Feurle, Patrick, Abentung, Andreas, Cera, Isabella, Wahl, Nico, Ablinger, Cornelia, Bucher, Michael, Stefan, Eduard, Sprenger, Simon, Teis, David, Fischer, Andre, Laighneach, Aodán, Whitton, Laura, Morris, Derek W, Apostolova, Galina, Dechant, Georg

“…SATB2 is a schizophrenia risk gene and is genetically associated with human intelligence. How it affects cognition at molecular level is currently unknown…”
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Contribution of ambient noise and hyperbaric atmosphere to olfactory and gustatory function by Fischer, Hans-Georg, Schmidtbauer, Christopher, Seiffart, Annett, Bucher, Michael, Plontke, Stefan K, Rahne, Torsten

“…Taste and smell are important for occupational performance and quality of life. Previous studies suggested that the function of these senses might be…”
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Tranexamic Acid for reduction of intra- and postoperative TRansfusion requirements in elective Abdominal surgery (TATRA): study protocol for an investigator-initiated, multicenter, double-blind, placebo-controlled, randomized superiority trial with two parallel groups by Ronellenfitsch, Ulrich, Kestel, Anita, Klose, Johannes, Rebelo, Artur, Bucher, Michael, Ebert, Daniel, Mikolajczyk, Rafael, Wienke, Andreas, Kegel, Thomas, Hering, Julian, Haiduk, Christian, Richter, Michael, Steighardt, Jörg, Grohmann, Erich, Otto, Lutz, Kleeff, Jörg

“…Intra- and postoperative hemorrhage is a relevant problem in major abdominal surgery, leading to acute anemia and necessitating transfusion of packed red blood…”
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Autism associated SHANK3 missense point mutations impact conformational fluctuations and protein turnover at synapses by Bucher, Michael, Niebling, Stephan, Han, Yuhao, Molodenskiy, Dmitry, Nia, Fatemeh Hassani, Kreienkamp, Hans-Jürgen, Svergun, Dmitri, Kim, Eunjoon, Kostyukova, Alla S, Kreutz, Michael R, Mikhaylova, Marina

“…Members of the SH3- and ankyrin-rich repeat (SHANK) protein family are considered as master scaffolds of the post-synaptic density of glutamatergic synapses…”
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Identification of proteotoxic and proteoprotective bacteria that non-specifically affect proteins associated with neurodegenerative diseases by Walker, Alyssa C., Bhargava, Rohan, Bucher, Michael J., Argote, Yoan M., Brust, Amanda S., Czyż, Daniel M.

“…There are no cures for neurodegenerative protein conformational diseases (PCDs), such as Alzheimer’s disease (AD), Parkinson’s disease (PD), and Huntington’s…”
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Regulation of renal sodium transporters during severe inflammation by SCHMIDT, Christoph, HÖCHERL, Klaus, SCHWEDA, Frank, KURTZ, Armin, BUCHER, Michael

“…Sepsis-associated acute renal failure is characterized by decreased GFR and tubular dysfunction. The pathogenesis of endotoxemic tubular dysfunction with…”
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Regulation of Expression of Renal Organic Anion Transporters OAT1 and OAT3 in a Model of Ischemia/Reperfusion Injury by Preising, Christina, Schneider, Reinhard, Bucher, Michael, Gekle, Michael, Sauvant, Christoph

“…Background: Recently, we gained evidence that impairment of rOat1 and rOat3 expression induced by ischemic acute kidney injury (AKI) is mediated by COX…”
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Necrotizing fasciitis caused by the treatment of chronic non-specific back pain by Floether, Lilit, Bucher, Michael, Benndorf, Ralf, Burgdorff, Anna-Maria

“…Chronic back pain is a multifactorial disease that occurs particularly in adults and has many negative effects on the quality of daily life. Therapeutic…”
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Regulation of renal glucose transporters during severe inflammation by Schmidt, Christoph, Höcherl, Klaus, Bucher, Michael

“…Severe sepsis is accompanied by acute renal failure (ARF) with renal tubular dysfunction and glucosuria. In this study, we aimed to determine the regulation of…”
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Cardiogenic shock with highly complicated course after influenza A virus infection treated with vva-ECMO and Impella CP (ECMELLA): a case report by Ebert, Daniel, Mungard, Nils, Mensch, Alexander, Homeister, Lorenz, Willsch, Jan, Ibe, Richard, Baust, Henning, Stiller, Markus, Rebelo, Artur, Ukkat, Joerg, Rigopoulos, Angelos G, Weber, Elke, Bucher, Michael, Noutsias, Michel

“…Abstract Background The value of mechanical circulatory support (MCS) in cardiogenic shock, especially the combination of the ECMELLA approach (Impella…”
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Mid-German Sepsis Cohort (MSC): a prospective observational study of sepsis survivorship by Fleischmann-Struzek, Carolin, Kesselmeier, Miriam, Ouart, Dominique, Hartog, Christiane S., Bauer, Michael, Bercker, Sven, Bucher, Michael, Meier-Hellmann, Andreas, Petros, Sirak, Schreiber, Torsten, Simon, Philipp, Weidhase, Lorenz, Born, Sebastian, Braune, Anke, Chkirni, Hicham, Eichhorn, Cornelia, Fiedler, Sandra, Gampe, Christin, König, Christian, Platzer, Stephanie, Romeike, Heike, Töpfer, Kristin, Reinhart, Konrad, Scherag, André

“…PurposeThe Mid-German Sepsis Cohort (MSC) aims to investigate mid-term and long-term functional disabilities in sepsis survivors from intensive care unit (ICU)…”
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Cytokine-mediated regulation of urea transporters during experimental endotoxemia by Schmidt, Christoph, Höcherl, Klaus, Bucher, Michael

“…Acute renal failure (ARF) is a frequent complication of sepsis and has a high mortality. Sepsis-induced ARF is known to be associated with significant…”
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Bioavailability of Mycophenolate Mofetil and Enteric-Coated Mycophenolate Sodium Is Differentially Affected by Pantoprazole in Healthy Volunteers by Rupprecht, Korbinian, Schmidt, Christoph, Raspé, Anne, Schweda, Frank, Shipkova, Maria, Fischer, Wolfgang, Bucher, Michael, Kees, Frieder, Faerber, Lothar

“…The influence of pantoprazole 40 mg twice daily on the bioavailability of a single dose of mycophenolate mofetil 1000 mg or enteric‐coated mycophenolate sodium…”
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Proinflammatory cytokines cause down-regulation of renal chloride entry pathways during sepsis by Schmidt, Christoph, Höcherl, Klaus, Schweda, Frank, Bucher, Michael

“…OBJECTIVE:Sepsis is the most important trigger for acute renal failure, with tubular dysfunction and collapse in urine concentration. As chloride plays a major…”
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Dual-Energy Computed Tomography Applications for the Evaluation of Cervical Lymphadenopathy by Tawfik, Ahmed M., MBBCH, MSc, MD, Michael Bucher, Andreas, MD, Vogl, Thomas J., MD

“…There is recent interest in the use of dual-energy computed tomography (CT) in head and neck imaging, and the results are encouraging. This article reviews…”
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Challenges in Implementing the Local Node Infrastructure for a National Federated Machine Learning Network in Radiology by Jacobs, Paul-Philipp, Ehrengut, Constantin, Bucher, Andreas Michael, Penzkofer, Tobias, Lukas, Mathias, Kleesiek, Jens, Denecke, Timm

“…Data-driven machine learning in medical research and diagnostics needs large-scale datasets curated by clinical experts. The generation of large datasets can…”
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