Search Results - "BUADI, Francis"
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Improved outcomes for newly diagnosed AL amyloidosis between 2000 and 2014: cracking the glass ceiling of early death
Published in Blood (13-04-2017)“…In light of major advances in immunoglobulin light chain (AL) amyloidosis, we evaluated the trends in presentation, management, and outcome among 1551 newly…”
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Remission of Disseminated Cancer After Systemic Oncolytic Virotherapy
Published in Mayo Clinic proceedings (01-07-2014)“…Abstract MV-NIS is an engineered measles virus that is selectively destructive to myeloma plasma cells and can be monitored by noninvasive radioiodine imaging…”
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Randomized Trial of Lenalidomide Versus Observation in Smoldering Multiple Myeloma
Published in Journal of clinical oncology (10-04-2020)“…Observation is the current standard of care for smoldering multiple myeloma. We hypothesized that early intervention with lenalidomide could delay progression…”
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Revised Prognostic Staging System for Light Chain Amyloidosis Incorporating Cardiac Biomarkers and Serum Free Light Chain Measurements
Published in Journal of clinical oncology (20-03-2012)“…Cardiac involvement predicts poor prognosis in light chain (AL) amyloidosis, and the current prognostic classification is based on cardiac biomarkers…”
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Chemotherapy‐based approach is the preferred treatment for sporadic late‐onset nemaline myopathy with a monoclonal protein
Published in International journal of cancer (01-06-2021)“…Sporadic late‐onset nemaline myopathy (SLONM) associated with monoclonal protein (MP) is a rare disease with an aggressive, and often fatal course. Whether…”
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Pros and cons of frontline autologous transplant in multiple myeloma: the debate over timing
Published in Blood (14-02-2019)“…The treatment landscape for multiple myeloma has dramatically changed over the past decade with the introduction of several new classes of drugs, which are…”
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Stem Cell Transplantation for Light Chain Amyloidosis: Decreased Early Mortality Over Time
Published in Journal of clinical oncology (01-05-2018)“…Purpose Autologous stem-cell transplantation (ASCT) has been used in patients with immunoglobulin light chain (AL) amyloidosis for more than two decades. Early…”
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Improved survival in multiple myeloma and the impact of novel therapies
Published in Blood (01-03-2008)“…Treatments for myeloma have expanded in the last decade, but it is not clear if the introduction of novel therapies and the increased use of high-dose therapy…”
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Management of Newly Diagnosed Symptomatic Multiple Myeloma: Updated Mayo Stratification of Myeloma and Risk-Adapted Therapy (mSMART) Consensus Guidelines 2013
Published in Mayo Clinic proceedings (01-04-2013)“…Abstract Multiple myeloma remains an incurable neoplasm of plasma cells that affects more than 20,000 people annually in the United States. There has been a…”
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Coexistent Multiple Myeloma or Increased Bone Marrow Plasma Cells Define Equally High-Risk Populations in Patients With Immunoglobulin Light Chain Amyloidosis
Published in Journal of clinical oncology (01-12-2013)“…There is consensus that patients with light chain (AL) amyloidosis with hypercalcemia, renal failure, anemia, and lytic bone lesions attributable to clonal…”
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A phase 1/2 study of an adjuvanted varicella-zoster virus subunit vaccine in autologous hematopoietic cell transplant recipients
Published in Blood (06-11-2014)“…Recombinant herpes zoster (HZ) vaccines may be an alternative to the live-attenuated HZ vaccine for immunocompromised individuals. This was a phase 1/2,…”
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Final Overall Survival Analysis of the TOURMALINE-MM1 Phase III Trial of Ixazomib, Lenalidomide, and Dexamethasone in Patients With Relapsed or Refractory Multiple Myeloma
Published in Journal of clinical oncology (01-08-2021)“…The double-blind, placebo-controlled, phase III TOURMALINE-MM1 study demonstrated a statistically significant improvement in progression-free survival with…”
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Utilization of hematopoietic stem cell transplantation for the treatment of multiple myeloma: a Mayo Stratification of Myeloma and Risk-Adapted Therapy (mSMART) consensus statement
Published in Bone marrow transplantation (Basingstoke) (01-03-2019)“…Over the last two decades, the utilization of various novel therapies in the upfront or salvage settings has continued to improve survival outcomes for…”
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Risk stratification of smoldering multiple myeloma incorporating revised IMWG diagnostic criteria
Published in Blood cancer journal (New York) (12-06-2018)“…In 2014, the International Myeloma Working Group reclassified patients with smoldering multiple myeloma (SMM) and bone marrow-plasma cell percentage (BMPC%) ≥…”
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Sarcopenia identified by computed tomography imaging using a deep learning–based segmentation approach impacts survival in patients with newly diagnosed multiple myeloma
Published in Cancer (01-02-2023)“…Background Sarcopenia increases with age and is associated with poor survival outcomes in patients with cancer. By using a deep learning–based segmentation…”
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Mortality trends in multiple myeloma after the introduction of novel therapies in the United States
Published in Leukemia (01-03-2022)“…Advances in the understanding of disease biology, drug development, and supportive care have led to improved outcomes in multiple myeloma. Given that these…”
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Management of Newly Diagnosed Symptomatic Multiple Myeloma: updated Mayo Stratification of Myeloma and Risk-Adapted Therapy (mSMART) Consensus Guidelines
Published in Mayo Clinic proceedings (01-12-2009)“…Multiple myeloma is a malignant plasma cell neoplasm that affects more than 20,000 people each year and is the second most common hematologic malignancy. It is…”
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Journal Article Conference Proceeding -
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A Modern Primer on Light Chain Amyloidosis in 592 Patients With Mass Spectrometry–Verified Typing
Published in Mayo Clinic proceedings (01-03-2019)“…To describe the clinical and laboratory characteristics of patients with meticulously typed light chain (AL) amyloidosis. Patients (N=592) with biopsy-proven,…”
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What do I need to know about immunoglobulin light chain (AL) amyloidosis?
Published in Blood reviews (01-07-2012)“…Abstract Immunoglobulin light chain (AL) amyloidosis is the most common acquired systemic amyloidoses. Its presentation is often insidious and progressive,…”
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