Search Results - "BRYAN, Richard"

Cell adhesion and urothelial bladder cancer: the role of cadherin switching and related phenomena by Bryan, Richard T.

“…Cadherins are mediators of cell–cell adhesion in epithelial tissues. E-cadherin is a known tumour suppressor and plays a central role in suppressing the…”
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Adjuvant chemotherapy in upper tract urothelial carcinoma (the POUT trial): a phase 3, open-label, randomised controlled trial by Birtle, Alison, Johnson, Mark, Chester, John, Jones, Robert, Dolling, David, Bryan, Richard T, Harris, Christopher, Winterbottom, Andrew, Blacker, Anthony, Catto, James W F, Chakraborti, Prabir, Donovan, Jenny L, Elliott, Paul Anthony, French, Ann, Jagdev, Satinder, Jenkins, Benjamin, Keeley, Francis Xavier, Kockelbergh, Roger, Powles, Thomas, Wagstaff, John, Wilson, Caroline, Todd, Rachel, Lewis, Rebecca, Hall, Emma

“…Urothelial carcinomas of the upper urinary tract (UTUCs) are rare, with poorer stage-for-stage prognosis than urothelial carcinomas of the urinary bladder. No…”
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Association between treatment of superficial bladder cancer and 10‐year mortality in older adults with multiple chronic conditions by Bryan, Richard T.

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Deep learning discrimination of quartz and resin in optical microscopy images of minerals by Iglesias, Julio César Álvarez, Santos, Richard Bryan Magalhaes, Paciornik, Sidnei

“…•Quartz cannot be discriminated from the mounting resin under optical microscopy.•A human being seems to be perfectly capable of differentiating quartz from…”
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The Clinical Research Office of the Endourological Society (CROES) Multicentre Randomised Trial of Narrow Band Imaging–Assisted Transurethral Resection of Bladder Tumour (TURBT) Versus Conventional White Light Imaging–Assisted TURBT in Primary Non–Muscle-invasive Bladder Cancer Patients: Trial Protocol and 1-year Results by Naito, Seiji, Algaba, Ferran, Babjuk, Marko, Bryan, Richard T, Sun, Ying-Hao, Valiquette, Luc, de la Rosette, Jean

“…Abstract Background White light (WL) is the established imaging modality for transurethral resection of bladder tumour (TURBT). Narrow band imaging (NBI) is a…”
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Co-expression of CD39 and CD103 identifies tumor-reactive CD8 T cells in human solid tumors by Duhen, Thomas, Duhen, Rebekka, Montler, Ryan, Moses, Jake, Moudgil, Tarsem, de Miranda, Noel F., Goodall, Cheri P., Blair, Tiffany C., Fox, Bernard A., McDermott, Jason E., Chang, Shu-Ching, Grunkemeier, Gary, Leidner, Rom, Bell, Richard Bryan, Weinberg, Andrew D.

“…Identifying tumor antigen-specific T cells from cancer patients has important implications for immunotherapy diagnostics and therapeutics. Here, we show that…”
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Quantified relations between exposure to tobacco smoking and bladder cancer risk: a meta-analysis of 89 observational studies by van Osch, Frits Hm, Jochems, Sylvia Hj, van Schooten, Frederik-Jan, Bryan, Richard T, Zeegers, Maurice P

“…Smoking is a major risk factor for bladder cancer (BC). This meta-analysis updates previous reviews on smoking characteristics and BC risk, and provides a more…”
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Cadherin switching and bladder cancer by Bryan, Richard T, Tselepis, Chris

“…Progression to or presentation with muscle invasive disease represents the critical clinical step in bladder cancer, necessitating more aggressive therapy and…”
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Multiplex PCR and Next Generation Sequencing for the Non-Invasive Detection of Bladder Cancer by Ward, Douglas G, Baxter, Laura, Gordon, Naheema S, Ott, Sascha, Savage, Richard S, Beggs, Andrew D, James, Jonathan D, Lickiss, Jennifer, Green, Shaun, Wallis, Yvonne, Wei, Wenbin, James, Nicholas D, Zeegers, Maurice P, Cheng, K K, Mathews, Glenn M, Patel, Prashant, Griffiths, Michael, Bryan, Richard T

“…Highly sensitive and specific urine-based tests to detect either primary or recurrent bladder cancer have proved elusive to date. Our ever increasing knowledge…”
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Significant reduction in diabetes distress and improvements in psychosocial outcomes: A pilot test of an intervention to reduce diabetes distress in adults with type 1 diabetes and moderate-to-severe diabetes distress (REDUCE) by Stenov, Vibeke, Due-Christensen, Mette, Cleal, Bryan Richard, Tapager, Ingrid Willaing

“…To pilot-test an intervention, co-designed with people with type 1 diabetes (T1DM) and diabetes specialist nurses, to reduce diabetes distress (DD) in adults…”
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Molecular Subtypes of T1 Bladder Cancer: Biomolecular Characteristics Versus Clinical Utility by Ward, Douglas G., Arnold, Roland, Bryan, Richard T.

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Methylation of HOXA9 and ISL1 Predicts Patient Outcome in High-Grade Non-Invasive Bladder Cancer by Kitchen, Mark O, Bryan, Richard T, Haworth, Kim E, Emes, Richard D, Luscombe, Christopher, Gommersall, Lyndon, Cheng, K K, Zeegers, Maurice P, James, Nicholas D, Devall, Adam J, Fryer, Anthony A, Farrell, William E

“…Inappropriate DNA methylation is frequently associated with human tumour development, and in specific cases, is associated with clinical outcomes. Previous…”
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Comparing an Imaging-guided Pathway with the Standard Pathway for Staging Muscle-invasive Bladder Cancer: Preliminary Data from the BladderPath Study by Bryan, Richard T., Liu, Wenyu, Pirrie, Sarah J., Amir, Rashid, Gallagher, Jean, Hughes, Ana I., Jefferson, Kieran P., Knight, Allen, Nanton, Veronica, Mintz, Harriet P., Pope, Ann M., Catto, James W.F., Patel, Prashant, James, Nicholas D.

“…Transurethral resection of bladder tumour (TURBT) is central to the diagnosis of muscle-invasive bladder cancer (MIBC). With the oncological safety of TURBT…”
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The Sirenic Links between Diabetes, Obesity, and Bladder Cancer by Gill, Emily, Sandhu, Gurimaan, Ward, Douglas G, Perks, Claire M, Bryan, Richard T

“…There is considerable evidence of a positive association between the incidence of type 2 diabetes mellitus (T2DM) and obesity with bladder cancer (BCa), with…”
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A deep learning system for collotelinite segmentation and coal reflectance determination by Santos, Richard Bryan Magalhães, Augusto, Karen Soares, Iglesias, Julio César Álvarez, Rodrigues, Sandra, Paciornik, Sidnei, Esterle, Joan S., Domingues, Alei Leite Alcantara

“…Coal is widely used in industrial applications such as carbonization and coke production for steel making, combustion, or gasification to generate electricity,…”
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An Updated Meta-Analysis of Treatment in Patients with Heart Failure Complicated Ventricular Functional Mitral Regurgitation by Sasmita, Bryan Richard, Luo, Suxin, Huang, Bi

“…Ventricular functional mitral regurgitation (FMR) is a common morbidity in patients with heart failure (HF). In addition to guideline-directed medical therapy,…”
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The need for supportive mental wellbeing interventions in bladder cancer patients: A systematic review of the literature by Bessa, Agustina, Rammant, Elke, Enting, Deborah, Bryan, Richard T, Shamim Khan, Muhammad, Malde, Sachin, Nair, Rajesh, Thurairaja, Ramesh, Cahill, Fidelma, Amery, Suzanne, Smith, Sue, Ahmed, Kamran, Russell, Beth, Moss, Charlotte, Chatterton, Kathryn, Häggström, Christel, Van Hemelrijck, Mieke

“…There is an increased awareness of the effect of a bladder cancer diagnosis and its treatments on the mental wellbeing of patients. However, few studies have…”
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Improved Disease-Free Survival With Adjuvant Chemotherapy After Nephroureterectomy for Upper Tract Urothelial Cancer: Final Results of the POUT Trial by Birtle, Alison Jane, Jones, Robert, Chester, John, Lewis, Rebecca, Biscombe, Katie, Johnson, Mark, Blacker, Anthony, Bryan, Richard T, Catto, James W F, Choudhury, Ananya, Das, Prantik, Jagdev, Satinder, Powles, Thomas, Wagstaff, John, Cheung, Ka Ching, Cafferty, Fay, Hall, Emma

“…JCO POUT was a phase III, randomized, open-label trial, including 261 patients with muscle-invasive or lymph node-positive, nonmetastatic upper tract…”
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Aryloxy Diester Phosphonamidate Prodrugs of Phosphoantigens (ProPAgens) as Potent Activators of Vγ9/Vδ2 T‑Cell Immune Responses by Kadri, Hachemi, Taher, Taher E, Xu, Qin, Sharif, Maria, Ashby, Elizabeth, Bryan, Richard T, Willcox, Benjamin E, Mehellou, Youcef

“…Vγ9/Vδ2 T-cells are activated by pyrophosphate-containing small molecules known as phosphoantigens (PAgs). The presence of the pyrophosphate group in these…”
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Centralisation of radical cystectomies for bladder cancer in England, a decade on from the ‘Improving Outcomes Guidance’: the case for super centralisation by Afshar, Mehran, Goodfellow, Henry, Jackson‐Spence, Francesca, Evison, Felicity, Parkin, John, Bryan, Richard T., Parsons, Helen, James, Nicholas D., Patel, Prashant

“…Objective To analyse the impact of centralisation of radical cystectomy (RC) provision for bladder cancer in England, on postoperative mortality, length of…”
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