Search Results - "BRUZZONE, Roberto"
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Breaking Bad: How Viruses Subvert the Cell Cycle
Published in Frontiers in cellular and infection microbiology (19-11-2018)“…Interactions between the host and viruses during the course of their co-evolution have not only shaped cellular function and the immune system, but also the…”
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Fc receptors in antibody-dependent enhancement of viral infections
Published in Immunological reviews (01-11-2015)“…Summary Sensitization of the humoral immune response to invading viruses and production of antiviral antibodies forms part of the host antiviral repertoire…”
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Lyn kinase regulates egress of flaviviruses in autophagosome-derived organelles
Published in Nature communications (15-10-2020)“…Among the various host cellular processes that are hijacked by flaviviruses, few mechanisms have been described with regard to viral egress. Here we…”
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Anti-Severe Acute Respiratory Syndrome Coronavirus Spike Antibodies Trigger Infection of Human Immune Cells via a pH- and Cysteine Protease-Independent FcγR Pathway
Published in Journal of Virology (01-10-2011)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Antibody-dependent infection of human macrophages by severe acute respiratory syndrome coronavirus
Published in Virology journal (06-05-2014)“…BACKGROUND: Public health risks associated to infection by human coronaviruses remain considerable and vaccination is a key option for preventing the…”
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Egg-adaptive mutations of human influenza H3N2 virus are contingent on natural evolution
Published in PLoS pathogens (26-09-2022)“…Egg-adaptive mutations in influenza hemagglutinin (HA) often emerge during the production of egg-based seasonal influenza vaccines, which contribute to the…”
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Pharmacological properties of homomeric and heteromeric pannexin hemichannels expressed in Xenopus oocytes
Published in Journal of neurochemistry (01-03-2005)“…Several new findings have emphasized the role of neuron‐specific gap junction proteins (connexins) and electrical synapses in processing sensory information…”
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Epistasis mediates the evolution of the receptor binding mode in recent human H3N2 hemagglutinin
Published in Nature communications (18-06-2024)“…The receptor-binding site of influenza A virus hemagglutinin partially overlaps with major antigenic sites and constantly evolves. In this study, we observe…”
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Cell-Cell Communication Beyond Connexins: The Pannexin Channels
Published in Physiology (Bethesda, Md.) (01-04-2006)“…Michael T. Barbe 1 , Hannah Monyer 1 and Roberto Bruzzone 2 1 Department of Clinical Neurobiology and Interdisciplinary Center for Neuroscience, University of…”
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Pannexins, a Family of Gap Junction Proteins Expressed in Brain
Published in Proceedings of the National Academy of Sciences - PNAS (11-11-2003)“…Database search has led to the identification of a family of proteins, the pannexins, which share some structural features with the gap junction forming…”
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Usp12 stabilizes the T-cell receptor complex at the cell surface during signaling
Published in Proceedings of the National Academy of Sciences - PNAS (09-02-2016)“…Posttranslational modifications are central to the spatial and temporal regulation of protein function. Among others, phosphorylation and ubiquitylation are…”
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Cleavage of the SARS coronavirus spike glycoprotein by airway proteases enhances virus entry into human bronchial epithelial cells in vitro
Published in PloS one (17-11-2009)“…Entry of enveloped viruses into host cells requires the activation of viral envelope glycoproteins through cleavage by either intracellular or extracellular…”
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Connexin hemichannel inhibition improves skin pathology in Clouston syndrome mice
Published in EBioMedicine (01-07-2020)Get full text
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Corrigendum: XAV-19, a swine glyco-humanized polyclonal antibody against SARS-CoV-2 spike receptor-binding domain, targets multiple epitopes and broadly neutralizes variants
Published in Frontiers in immunology (28-04-2023)“…[This corrects the article DOI: 10.3389/fimmu.2021.761250.]…”
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Tumor-suppressive effects of pannexin 1 in C6 glioma cells
Published in Cancer research (Chicago, Ill.) (15-02-2007)“…Mammalian gap junction proteins, connexins, have long been implicated in tumor suppression. Recently, a novel family of proteins named pannexins has been…”
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XAV-19, a Swine Glyco-Humanized Polyclonal Antibody Against SARS-CoV-2 Spike Receptor-Binding Domain, Targets Multiple Epitopes and Broadly Neutralizes Variants
Published in Frontiers in immunology (15-11-2021)“…Amino acid substitutions and deletions in the Spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants can reduce the…”
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First genetic evidence of GABAA receptor dysfunction in epilepsy: a mutation in the γ2-subunit gene
Published in Nature genetics (01-05-2001)Get full text
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Age-related seroprevalence trajectories of seasonal coronaviruses in children including neonates in Guangzhou, China
Published in International journal of infectious diseases (01-02-2023)“…•Seroprevalences of the four human coronaviruses (HCoVs) in children showed similar trajectories.•Immunoglobulin G levels of the four HCoVs in mothers and…”
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Class II ADP-ribosylation Factors Are Required for Efficient Secretion of Dengue Viruses
Published in The Journal of biological chemistry (02-01-2012)“…Identification and characterization of virus-host interactions are very important steps toward a better understanding of the molecular mechanisms responsible…”
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Ezrin interacts with the SARS coronavirus Spike protein and restrains infection at the entry stage
Published in PloS one (21-11-2012)“…Entry of Severe Acute Respiratory Syndrome coronavirus (SARS-CoV) and its envelope fusion with host cell membrane are controlled by a series of complex…”
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