Search Results - "BRUSA, Paola"
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Immunotoxins and anticancer drug conjugate assemblies: the role of the linkage between components
Published in Toxins (01-07-2011)“…Immunotoxins and antibody-drug conjugates are protein-based drugs combining a target-specific binding domain with a cytotoxic domain. Such compounds are…”
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Editorial: Medicinal Cannabis: evolution of therapeutic use, future approaches and other implications, volume II
Published in Frontiers in pharmacology (2023)Get full text
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Triptans utilization in Italian population: A real-life study in community pharmacies
Published in PloS one (08-09-2023)“…The term Headache Disorders (HD) refers to a number of nervous system pathologies characterised by recurrent headaches. Despite the serious impact HD have on…”
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Self-medication for migraine: A nationwide cross-sectional study in Italy
Published in PloS one (23-01-2019)“…Headache disorders are considered the second leading cause of years lived with disability worldwide, and 90% of people have a headache episode at least once a…”
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Editorial: Medicinal Cannabis: Evolution of therapeutic use, future approaches and other implications
Published in Frontiers in pharmacology (25-08-2022)Get full text
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Monitoring adherence to pharmacological therapy and follow-up examinations among patients with type 2 diabetes in community pharmacies. Results from an experience in Italy
Published in PloS one (07-09-2021)“…Introduction Type 2 diabetes is an important public health issue, yet adherence to drugs and regular clinical follow-up is still suboptimal. This study aims to…”
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An Emerging Strategy for Neuroinflammation Treatment: Combined Cannabidiol and Angiotensin Receptor Blockers Treatments Effectively Inhibit Glial Nitric Oxide Release
Published in International journal of molecular sciences (01-11-2023)“…Cannabidiol (CBD), the major non-psychoactive phytocannabinoid found in cannabis, has anti-neuroinflammatory properties. Despite the increasing use of CBD,…”
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Cannabis -Based Oral Emulsion for Medical Purposes to Meet the Needs of Patients: Formulation, Quality and Stability
Published in Pharmaceutics (25-02-2022)“…Current Italian legislation provides that medical can be administered orally as an extract if it has been titrated to determine the concentration of active…”
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Opportunistic screening for type 2 diabetes in community pharmacies. Results from a region-wide experience in Italy
Published in PloS one (18-03-2020)“…Given the paucity of symptoms in the early stages of type 2 diabetes, its diagnosis is often made when complications have already arisen. Although systematic…”
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Improvement in diagnostic-therapeutic care pathways for women with migraine: an Italian Delphi panel
Published in Frontiers in neurology (05-09-2024)“…Migraine is a highly underestimated and burdensome disease. Real-world studies evidence that migraine is more frequent and severe in women than men. However,…”
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Developing Actively Targeted Nanoparticles to Fight Cancer: Focus on Italian Research
Published in Pharmaceutics (22-09-2021)“…Active targeting is a valuable and promising approach with which to enhance the therapeutic efficacy of nanodelivery systems, and the development of…”
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Cannabis -Based Oral Formulations for Medical Purposes: Preparation, Quality and Stability
Published in Pharmaceuticals (Basel, Switzerland) (22-02-2021)“…Current legislation in Italy provides that medical may be administered orally or by inhalation. One of the fundamental criteria for the administration of oral…”
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Development of Standard Operating Protocols for the Optimization of Cannabis -Based Formulations for Medical Purposes
Published in Frontiers in pharmacology (25-06-2019)“…Under current legislation in Italy, for medical purposes may be administered orally in the form of decoction or oil extract. The scientific literature reports…”
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Preparation, characterization, cytotoxicity and pharmacokinetics of liposomes containing lipophilic gemcitabine prodrugs
Published in Journal of controlled release (10-12-2004)“…Gemcitabine is a known anticancer agent rapidly deaminated to the inactive metabolite 2′,2′-difluorodeoxyuridine; it must therefore be administered at very…”
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How to promote vaccinations: a pilot study in the North-West of Italy
Published in Human vaccines & immunotherapeutics (04-05-2019)“…Background: vaccines are one of the greatest medical discoveries. In various countries, pharmacists are authorised to administer vaccines directly in…”
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Preparation, characterization, cytotoxicity and pharmacokinetics of liposomes containing docetaxel
Published in Journal of controlled release (04-09-2003)“…The taxanes, paclitaxel and docetaxel, are anticancer agents used in clinical trials against ovarian carcinoma, breast, lung and head/neck cancer. Paclitaxel,…”
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Diffusion of counterfeit drugs in developing countries and stability of galenics stored for months under different conditions of temperature and relative humidity
Published in Croatian medical journal (01-04-2012)“…To investigate the diffusion of counterfeit medicines in developing countries and to verify the stability of galenic dosage forms to determine the stability of…”
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Preparation, characterization and properties of sterically stabilized paclitaxel-containing liposomes
Published in Journal of controlled release (03-01-2000)“…Paclitaxel (Taxol) is a diterpenoid isolated from Taxus brevifolia, approved by the FDA for the treatment of ovarian and breast cancers. Due to its low…”
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Antitumor Activity and Pharmacokinetics of Liposomes Containing Lipophilic Gemcitabine Prodrugs
Published in Anticancer research (01-01-2007)“…Background: Gemcitabine is a deoxycytidine analogue that exhibits antitumoral activity against adenocarcinomas of the colon, lung and pancreas. After…”
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Poly(ethylene glycol)–human serum albumin–paclitaxel conjugates: preparation, characterization and pharmacokinetics
Published in Journal of controlled release (11-09-2001)“…Paclitaxel has been found to be very effective against several human cancers, such as ovarian, breast and non-small cell lung cancer and has received marketing…”
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