Search Results - "BRUNNER, H. R"

Angiotensin II receptor antagonists by Burnier, M, Brunner, HR

“…Blockade of the renin-angiotensin system began as a way of studying the pathogenesis of cardiovascular disease with specific pharmacological probes. Oral…”
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The new oral angiotensin II antagonist olmesartan medoxomil: a concise overview by BRUNNER, H. R

“…The new orally active angiotensin II (A II) type-1 receptor antagonist olmesartan medoxomil is a prodrug, which is rapidly converted in vivo to the active…”
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Renal effects of selective cyclooxygenase-2 inhibition in normotensive salt-depleted subjects by Rossat, Julien, Maillard, Marc, Nussberger, Jürg, Brunner, Hans R., Burnier, Michel

“…Purpose To compare the renal hemodynamic and tubular effects of celecoxib, a selective inhibitor of cyclooxygenase‐2 (COX‐2) to those of naproxen, a…”
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Cardiovascular response, feeding behavior and locomotor activity in mice lacking the NPY Y1 receptor by Pedrazzini, Thierry, Seydoux, Josiane, Künstner, Pierre, Aubert, Jean-François, Grouzmann, Eric, Beermann, Friedrich, Brunner, Hans R

“…Neuropeptide Y (NPY) is a 36-amino-acid neurotransmitter which is widely distributed throughout the central and peripheral nervous system. NPY involvement has…”
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Influence of Oscillatory and Unidirectional Flow Environments on the Expression of Endothelin and Nitric Oxide Synthase in Cultured Endothelial Cells by Ziegler, Thierry, Bouzourene, Karima, Harrison, Vanessa J, Brunner, Hans R, Hayoz, Daniel

“…In vivo, endothelial cells (ECs) are subjected to a complex mechanical environment composed of shear stress, pressure, and circumferential stretch. The aim of…”
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Increased Cardiac Angiotensin II Levels Induce Right and Left Ventricular Hypertrophy in Normotensive Mice by Mazzolai, Lucia, Pedrazzini, Thierry, Nicoud, Françoise, Gabbiani, Giulio, Brunner, Hans-R, Nussberger, Jürg

“…Angiotensin II is a potent arterial vasoconstrictor and induces hypertension. Angiotensin II also exerts a trophic effect on cardiomyocytes in vitro. The goals…”
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Blood Pressure-Independent Cardiac Hypertrophy Induced by Locally Activated Renin-Angiotensin System by Mazzolai, Lucia, Nussberger, Jurg, Aubert, Jean-Francois, Brunner, Dorette B, Gabbiani, Giulio, Brunner, Hans R, Pedrazzini, Thierry

“…Cardiac hypertrophy is frequent in chronic hypertension. The renin-angiotensin system, via its effector angiotensin II (Ang II), regulates blood pressure and…”
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Oral administration of DuP 753, a specific angiotensin II receptor antagonist, to normal male volunteers : inhibition of pressor response to exogenous angiotensin I and II by CHRISTEN, Y, WAEBER, B, NUSSBERGER, J, PORCHET, M, BORLAND, R. M, LEE, R. J, MAGGON, K, SHUM, L, TIMMERMANS, P. B. M. W. M, BRUNNER, H. R

“…The purpose of the present study was to assess the inhibitory effect of DuP 753, an orally active angiotensin II receptor antagonist, on the pressor action of…”
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Pharmacokinetic and pharmacodynamic effects of YM087, a combined V1/V2 vasopressin receptor antagonist in normal subjects by BURNIER, M, FRICKER, A. F, HAYOZ, D, NUSSBERGER, J, BRUNNER, H. R

“…The pharmacokinetic and pharmacodynamic properties of YM087, (4'-[(2-methyl-1,4,5,6- tetrahydroimidazo[4,5-d][1]benzazepin-6-yl)-carbonyl]-2-p henylbenzanilide…”
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Comparative effects of losartan and irbesartan on serum uric acid in hypertensive patients with hyperuricaemia and gout by Würzner, Grégoire, Gerster, Jean-Charles, Chiolero, Arnaud, Maillard, Marc, Fallab-Stubi, Claire-Lise, Brunner, Hans R, Burnier, Michel

“…OBJECTIVE Losartan has been shown to increase urinary uric acid excretion and hence to lower serum uric acid levels. The purposes of the present study were(1)…”
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Endothelial function in chronic congestive heart failure by Drexler, Helmut, Hayoz, Daniel, Münzel, Thomas, Hornig, Burckhardt, Just, Hanjörg, Brunner, Hans R., Zelis, Robert

“…There is evidence that the endothelium plays an important role in the control of human vascular tone by releasing endothelium-derived nitric oxide. The…”
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Calcineurin Blockade Prevents Cardiac Mitogen-activated Protein Kinase Activation and Hypertrophy in Renovascular Hypertension by Murat, Anastasia, Pellieux, Corinne, Brunner, Hans-R., Pedrazzini, Thierry

“…Chronic stimulation of the renin-angiotensin system induces an elevation of blood pressure and the development of cardiac hypertrophy via the actions of its…”
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The multifactorial nature of hypertension: the greatest challenge for its treatment? by Waeber, B, Brunner, H R

“…Essential hypertension is a polygenic disease involving a major contribution of various environmental factors. It is therefore not surprising that…”
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Effects of chronic NO synthase inhibition in rats on renin-angiotensin system and sympathetic nervous system by Zanchi, A, Schaad, N C, Osterheld, M C, Grouzmann, E, Nussberger, J, Brunner, H R, Waeber, B

“…This study was designed to assess the role of renin and of the sympathoadrenal system in the maintenance of the hypertension induced by chronic nitric oxide…”
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Renal effects of angiotensin II receptor blockade in normotensive subjects by Burnier, Michel, Roch-Ramel, Françoise, Brunner, Hans R.

“…Renal effects of angiotensin II receptor blockade in normotensive subjects. Several new non-peptide, orally active, angiotensin II receptor antagonists have…”
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Determinants of Angiotensin II Generation During Converting Enzyme Inhibition by Juillerat, Lucienne, Nussberger, Jürg, Ménard, Joël, Mooser, Vincent, Christen, Yves, Waeber, Bernard, Graf, Peter, Brunner, Hans R

“…The reaction of the renin-angiotensin system to acute angiotensin converting enzyme inhibition was investigated in a single-blind, crossover study in nine…”
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Confocal microscopy to analyze cytosolic and nuclear calcium in cultured vascular cells by Burnier, M, Centeno, G, Burki, E, Brunner, H R

“…With the development of calcium-sensitive fluorescent dyes and videomicroscopic imaging, several investigators have located the changes in intracellular…”
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Compliance with Antihypertensive Therapy by Waeber, B., Burnier, M., Brunner, H. R.

“…Poor compliance with antihypertensive therapy is a major cause of unsatisfactory blood pressure control. The doctor has a key role in all steps that lead the…”
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Improved blood pressure control by monitoring compliance with antihypertensive therapy by Waeber, B, Vetter, W, Darioli, R, Keller, U, Brunner, H R

“…Compliance with antihypertensive therapy was monitored for three months using an electronic medication dispenser in 35 patients remaining hypertensive despite…”
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Isolated office hypertension: a prehypertensive state? by Bidlingmeyer, I, Burnier, M, Bidlingmeyer, M, Waeber, B, Brunner, H R

“…Isolated office hypertension, defined as hypertensive blood pressure values in a medical setting but normal self-measured or ambulatory-recorded blood…”
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