Search Results - "BRUNETTO, Maurizia R"

HBeAg-Negative/Anti-HBe-Positive Chronic Hepatitis B: A 40-Year-Old History by Bonino, Ferruccio, Colombatto, Piero, Brunetto, Maurizia R

“…Hepatitis B “e” antigen (HBeAg) negative chronic hepatitis B (CHB), 40 years since discovery in the Mediterranean area, has become the most prevalent form of…”
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Statements from the Taormina expert meeting on occult hepatitis B virus infection by Raimondo, Giovanni, Allain, Jean-Pierre, Brunetto, Maurizia R, Buendia, Marie-Annick, Chen, Ding-Shinn, Colombo, Massimo, Craxì, Antonio, Donato, Francesco, Ferrari, Carlo, Gaeta, Giovanni B, Gerlich, Wolfram H, Levrero, Massimo, Locarnini, Stephen, Michalak, Thomas, Mondelli, Mario U, Pawlotsky, Jean-Michel, Pollicino, Teresa, Prati, Daniele, Puoti, Massimo, Samuel, Didier, Shouval, Daniel, Smedile, Antonina, Squadrito, Giovanni, Trépo, Christian, Villa, Erica, Will, Hans, Zanetti, Alessandro R, Zoulim, Fabien

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Management and Treatment of Patients with Chronic Hepatitis B: Towards Personalized Medicine by Colombatto, Piero, Coco, Barbara, Bonino, Ferruccio, Brunetto, Maurizia R

“…The currently available antiviral treatments (Peg-Interferon-α and Nucleos(t)ide Analogues, NA) for chronic hepatitis B (CHB) achieve a functional cure (serum…”
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Hepatitis B Core-Related Antigen to Indicate High Viral Load: Systematic Review and Meta-Analysis of 10,397 Individual Participants by Yoshida, Kyoko, Desbiolles, Alice, Feldman, Sarah F., Ahn, Sang Hoon, Alidjinou, Enagnon K., Atsukawa, Masanori, Bocket, Laurence, Brunetto, Maurizia R., Buti, Maria, Carey, Ivana, Caviglia, Gian Paolo, Chen, En-Qiang, Cornberg, Markus, Enomoto, Masaru, Honda, Masao, Zu Siederdissen, Christoph Höner, Ishigami, Masatoshi, Janssen, Harry L.A., Maasoumy, Benjamin, Matsui, Takeshi, Matsumoto, Akihiro, Nishiguchi, Shuhei, Riveiro-Barciela, Mar, Takaki, Akinobu, Tangkijvanich, Pisit, Toyoda, Hidenori, van Campenhout, Margo J.H., Wang, Bo, Wei, Lai, Yang, Hwai-I, Yano, Yoshihiko, Yatsuhashi, Hiroshi, Yuen, Man-Fung, Tanaka, Eiji, Lemoine, Maud, Tanaka, Yasuhito, Shimakawa, Yusuke

“…To eliminate hepatitis B virus (HBV) infection, scale-up of testing and treatment in resource-limited countries is crucial. However, access to nucleic acid…”
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Hepatitis B Virus RNA Detection and a Mindful Use of Serum Hepatitis B Virus DNA and Hepatitis B Surface Antigen Measures in Clinical Practice by Brunetto, Maurizia R.

“…[...]the administration of siRNAs targeting integrated HBV DNA sequences resulted in significant HBsAg declines. [...]in samples obtained at baseline and…”
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Circulating hepatitis B surface antigen particles carry hepatocellular microRNAs by Novellino, Luisa, Rossi, Riccardo L, Bonino, Ferruccio, Cavallone, Daniela, Abrignani, Sergio, Pagani, Massimiliano, Brunetto, Maurizia R

“…Hepatitis B virus (HBV) produces high quantities of subviral surface antigen particles (HBsAg) which circulate in the blood outnumbering virions of about…”
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The natural history of chronic HBV infection and geographical differences by Liaw, Yun-Fan, Brunetto, Maurizia R, Hadziyannis, Stephanos

“…Although chronic HBV infection is a global health issue, there are geographical differences in the mode of transmission, prevalence and HBV genotype…”
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Trends in chronic hepatitis B virus infection in Italy over a 10-year period: Clues from the nationwide PITER and MASTER cohorts toward elimination by Brancaccio, Giuseppina, Coco, Barbara, Nardi, Alessandra, Quaranta, Maria Giovanna, Tosti, Maria Elena, Ferrigno, Luigina, Cacciola, Irene, Messina, Vincenzo, Chessa, Luchino, Morisco, Filomena, Milella, Michele, Barbaro, Francesco, Ciancio, Alessia, Russo, Francesco Paolo, Coppola, Nicola, Blanc, Pierluigi, Claar, Ernesto, Verucchi, Gabriella, Puoti, Massimo, Zignego, Anna Linda, Chemello, Liliana, Madonia, Salvatore, Fagiuoli, Stefano, Marzano, Alfredo, Ferrari, Carlo, Lampertico, Pietro, Di Marco, Vito, Craxì, Antonio, Santantonio, Teresa Antonia, Raimondo, Giovanni, Brunetto, Maurizia R., Gaeta, Giovanni Battista, Kondili, Loreta A., Pasulo, Luisa, Coppola, Carmine, Pisano, Federica, Romano, Mariarosaria, Porcu, Carmen, Bottalico, Irene Francesca, Cossiga, Valentina, Tata, Xhimi, Sagnelli, Caterina, Pierotti, Piera, Degasperi, Elisabetta, Rosato, Valerio, Badia, Lorenzo, Ieluzzi, Dontella, Monti, Monica, Bavetta, Maria Grazia, Cavalletto, Luisa, Toniutto, Pierluigi, Fornasiere, Ezio, Colecchia, Antonio, Ferrarese, Alberto, Nardone, Gerardo, Rocco, Alba, Viganò, Mauro, Foschi, Francesco Giuseppe, Conti, Fabio, Morsica, Giulia, Salpietro, Stefania, Torti, Carlo, Costa, Chiara, Federico, Alessandro, Dallio, Marcello, Giorgini, Alessia, Anselmo, Marco, De Leo, Pasqualina, Zaltron, Serena, Cambianica, Anna, Piscaglia, Fabio, Serio, Ilaria, Schivazappa, Simona, Mastroianni, Antonio, Chidichimo, Luciana, Massari, Marco, Mazzaro, Cesare, Marrone, Aldo, D'Amore, Francesca Maria, D'Offizi, Gianpiero, Licata, Anna, Niro, Grazia Anna, Pollicino, Teresa, Aghemo, Alessio

“…•Patients with chronic hepatitis B virus are older than in the past.•About 22% of the patients are migrants; they are younger than Italians.•The widespread use…”
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Inhibition of natural killer cells through engagement of CD81 by the major hepatitis C virus envelope protein by Crotta, Stefania, Stilla, Annalisa, Wack, Andreas, D'Andrea, Annalisa, Nuti, Sandra, D'Oro, Ugo, Mosca, Marta, Filliponi, Franco, Brunetto, R Maurizia, Bonino, Ferruccio, Abrignani, Sergio, Valiante, Nicholas M

“…The immune response against hepatitis C virus (HCV) is rarely effective at clearing the virus, resulting in approximately 170 million chronic HCV infections…”
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Longitudinal evaluation reveals a complex spectrum of virological profiles in hepatitis B virus/hepatitis C virus-coinfected patients by RAIMONDO, Giovanni, BRUNETTO, Maurizia R, PONTISSO, Patrizia, SMEDILE, Antonina, MAINA, Anna Maria, SAITTA, Carlo, SQUADRITO, Giovanni, TONO, Natascia

“…Hepatitis B virus (HBV) and hepatitis C virus (HCV) coinfection is often associated with severe forms of liver disease. However, comprehensive studies are…”
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No association between IFNL3 (IL28B) genotype and response to peginterferon alfa-2a in HBeAg-positive or -negative chronic hepatitis B by Wei, Lai, Wedemeyer, Heiner, Liaw, Yun-Fan, Chan, Henry Lik-Yuen, Piratvisuth, Teerha, Marcellin, Patrick, Jia, Jidong, Tan, Deming, Chow, Wan-Cheng, Brunetto, Maurizia R, Diago, Moisés, Gurel, Selim, Morozov, Viacheslav, He, Hua, Zhu, Yonghong, Wat, Cynthia, Surujbally, Bernadette, Thompson, Alexander J

“…It has yet to be firmly established whether host IFNL3 (IL28B) genotype influences interferon responsiveness in patients with chronic hepatitis B. We…”
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Reply to: “Increase in HDV replication during steroid therapy – potential implications for testing and treatment strategies” by Ricco, Gabriele, Brunetto, Maurizia R.

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Case Report: MIS-C With Prominent Hepatic and Pancreatic Involvement in a Vaccinated Adolescent - A Critical Reasoning by Consolini, Rita, Costagliola, Giorgio, Spada, Erika, Colombatto, Piero, Orsini, Alessandro, Bonuccelli, Alice, Brunetto, Maurizia R, Peroni, Diego G

“…Multisystem inflammatory syndrome in children (MIS-C) is a pathologic condition that has emerged during the coronavirus disease 2019 (COVID-19) pandemic…”
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Role of sex in liver tumor occurrence and clinical outcomes: A comprehensive review by Toniutto, Pierluigi, Shalaby, Sarah, Mameli, Laura, Morisco, Filomena, Gambato, Martina, Cossiga, Valentina, Guarino, Maria, Marra, Fabio, Brunetto, Maurizia R, Burra, Patrizia, Villa, Erica

“…Clinical research on sex-based differences in the manifestations, pathophysiology, and prevalence of several diseases, including those affecting the liver, has…”
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Guidance for design and endpoints of clinical trials in chronic hepatitis B - Report from the 2019 EASL-AASLD HBV Treatment Endpoints Conference by Cornberg, Markus, Lok, Anna Suk-Fong, Terrault, Norah A., Zoulim, Fabien, Berg, Thomas, Brunetto, Maurizia R., Buchholz, Stephanie, Buti, Maria, Chan, Henry L.Y., Chang, Kyong-Mi, Dandri, Maura, Dusheiko, Geoffrey, Feld, Jordan J., Ferrari, Carlo, Ghany, Marc, Janssen, Harry L.A., Kennedy, Patrick, Lampertico, Pietro, Liang, Jake, Locarnini, Stephen, Maini, Mala K., Mishra, Poonam, Papatheodoridis, George, Petersen, Jörg, Schlottmann, Silke, Wang, Su, Wedemeyer, Heiner

“…Representatives from academia, industry, regulatory agencies, and patient groups convened in March 2019 with the primary goal of developing agreement on…”
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TLR7 Agonist Increases Responses of Hepatitis B Virus–Specific T Cells and Natural Killer Cells in Patients With Chronic Hepatitis B Treated With Nucleos(T)Ide Analogues by Boni, Carolina, Vecchi, Andrea, Rossi, Marzia, Laccabue, Diletta, Giuberti, Tiziana, Alfieri, Arianna, Lampertico, Pietro, Grossi, Glenda, Facchetti, Floriana, Brunetto, Maurizia R., Coco, Barbara, Cavallone, Daniela, Mangia, Alessandra, Santoro, Rosanna, Piazzolla, Valeria, Lau, Audrey, Gaggar, Anuj, Subramanian, G. Mani, Ferrari, Carlo

“…The oral Toll-like receptor (TLR) 7 agonist GS-9620 has antiviral effects in woodchuck and chimpanzee models of chronic hepatitis B virus (HBV) infection. We…”
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Safety, efficacy and pharmacodynamics of vesatolimod (GS-9620) in virally suppressed patients with chronic hepatitis B by Janssen, Harry L.A., Brunetto, Maurizia R., Kim, Yoon Jun, Ferrari, Carlo, Massetto, Benedetta, Nguyen, Anh-Hoa, Joshi, Adarsh, Woo, Jacky, Lau, Audrey H., Gaggar, Anuj, Subramanian, G. Mani, Yoshida, Eric M., Ahn, Sang Hoon, Tsai, Naoky C.S., Fung, Scott, Gane, Edward J.

“…[Display omitted] •Vesatolimod was safe and well-tolerated in patients with chronic HBV infection.•Dose-dependent pharmacodynamic induction of ISGs was…”
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Nutritional intervention in the management of non-alcoholic fatty liver disease by Brunetto, Maurizia R., Salvati, Antonio, Petralli, Giovanni, Bonino, Ferruccio

“…Lifestyle modification is the primary intervention to control NAFLD progression, but despite evidence-based effectiveness it is difficult to distinguish the…”
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Diagnostic markers of chronic hepatitis B infection and disease by Bonino, Ferruccio, Piratvisuth, Teerha, Brunetto, Maurizia R, Liaw, Yun-Fan

“…Recent advances in therapy for patients with chronic hepatitis B (CHB) infection offer the potential for a more successful treatment outcome, but also raise a…”
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Combined GS-4774 and Tenofovir Therapy Can Improve HBV-Specific T-Cell Responses in Patients With Chronic Hepatitis by Boni, Carolina, Janssen, Harry L.A., Rossi, Marzia, Yoon, Seung Kew, Vecchi, Andrea, Barili, Valeria, Yoshida, Eric M., Trinh, Huy, Rodell, Timothy C., Laccabue, Diletta, Alfieri, Arianna, Brillo, Federica, Fisicaro, Paola, Acerbi, Greta, Pedrazzi, Giuseppe, Andreone, Pietro, Cursaro, Carmela, Margotti, Marzia, Santoro, Rosanna, Piazzolla, Valeria, Brunetto, Maurizia R., Coco, Barbara, Cavallone, Daniela, Zhao, Yang, Joshi, Adarsh, Woo, Jacky, Lau, Audrey H., Gaggar, Anuj, Subramanian, G. Mani, Massetto, Benedetta, Fung, Scott, Ahn, Sang Hoon, Ma, Xiaoli, Mangia, Alessandra, Ferrari, Carlo

“…One strategy to treat chronic hepatitis B virus (HBV) infection could be to increase the functions of virus-specific T cells. We performed a multicenter phase…”
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