Search Results - "BRUM JUNIOR, Liberato"

Development and Validation of an HPLC/MS/MS Method for the Determination of Sufentanil and Morphine in Human Plasma by LARGER MANFIO, Josélia, SANTOS, Verônica Jorge, LANCHOTE, Vera Lúcia, SANTOS, Luciana M, CARMONA, Maria José C, AULER, José Otavio, BRUM JUNIOR, Liberato, DONADUZZI, Carmen Maria, SANTOS, Silvia R. C. J

“…A sensitive and fast HPLC/MS/MS method for measurement of sufentanil and morphine in plasma was developed and validated. A single liquid-liquid extraction in…”
Get full text

Biological bases for a possible effect of cannabidiol in Parkinson's disease by Ferreira-Junior, Nilson C, Campos, Alline C, Guimarães, Francisco S, Del-Bel, Elaine, Zimmermann, Patrícia M da R, Brum Junior, Liberato, Hallak, Jaime E, Crippa, José A, Zuardi, Antonio W

“…Current pharmacotherapy of Parkinson's disease (PD) is palliative and unable to modify the progression of neurodegeneration. Treatments that can improve…”
Get full text

Effect of two oral formulations of cannabidiol on responses to emotional stimuli in healthy human volunteers: pharmaceutical vehicle matters by Crippa, José A, Pereira Junior, Luiz C, Pereira, Lívia C, Zimmermann, Patrícia M, Brum Junior, Liberato, Rechia, Letícia M, Dias, Isabella, Hallak, Jaime E, Campos, Alline C, Guimarães, Francisco S, Queiroz, Regina H, Zuardi, Antonio W

“…To compare plasma concentrations of cannabidiol (CBD) following oral administration of two formulations of the drug (powder and dissolved in oil), and to…”
Get full text

Development and Validation of LC-MS/MS Method for the Simultaneous Determination of Quinine and Doxycycline in Pharmaceutical Formulations by Junior, Liberato Brum, de Toni Uchoa, Flávia, Guterres, Sílvia Stanisçuaski, Costa, Teresa Dalla

“…A fast, sensitive, and specific liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was developed and validated for the simultaneous determination…”
Get full text

LC and LC-MS Evaluation of Stress Degradation Behavior of Carvedilol by Lanzanova, Fibele Analine, Argenta, Débora, Arend, Marcela Zart, Junior, Liberato Brum, Cardoso, Simone Gonçalves

“…In the present study, forced and accelerated degradation studies of carvedilol (CAR) were carried out according to ICH guideline Q1A (R2). The drug was…”
Get full text

DEVELOPMENT AND VALIDATION OF AN LC-MS/MS METHOD FOR THE PRE-CLINICAL PHARMACOKINETIC INVESTIGATION OF THE ANTICANCER CANDIDATE AC04 IN RODENTS by De Toni Uchôa, Flávia, Haas, Sandra Elisa, Junior, Liberato Brum, Pigatto, Maiara Cássia, de Lima, Maria do Carmo Alves, Galdino, Suely Lins, da Rocha Pitta, Ivan, Costa, Teresa Dalla

“…A liquid chromatography-tandem mass spectrometry method was developed for accurate quantification of the acridinic anticancer candidate AC04…”
Get full text

Determination of etoricoxib in human plasma using automated on-line solid-phase extraction coupled with LC-APCI/MS/MS by Dalmora, Sérgio Luiz, Brum Junior, Liberato, Ferretto, Ricardo Machado, Oliveira, Paulo Renato de, Barth, Thiago, Sangoi, Maximiliano da Silva

“…A liquid chromatography-tandem mass spectrometry method with atmospheric pressure chemical ionization (LC-APCI/MS/MS) was validated for the determination of…”
Get full text

Validation of a Liquid Chromatographic Method for the Determination of Acyclovir in Human Plasma: Application to Bioequivalence Study by Junior, Liberato Brum, Pugens, Ana Maria, Dal'Maso, Alexandre, Gomes, Eduardo, dos Santos, Maurício Bedim, Manfio, Josélia Larger

“…An analytical method based on reversed phase liquid chromatography (RP-LC) was developed and validated for the determination of acyclovir in human plasma…”
Get full text

Validation of the anti-factor Xa assay for the potency assessment of enoxaparin in pharmaceutical formulations by LUIZ DALMORA, Sérgio, BRUM JUNIOR, Liberato, SCHMIDT, Cleber Alberto, FERREIRA VACCARI, Silvana, RENATO OLIVEIRA, Paulo, FRANCO CODEVILLA, Cristiane

“…Enoxaparin is a low-molecular weight heparin used clinically for the prevention and treatment of venous and arterial thrombosis. An anti-factor Xa assay was…”
Get full text

Effect of two oral formulations of cannabidiol on responses to emotional stimuli in healthy human volunteers: pharmaceutical vehicle matters by Crippa, José A., Pereira Junior, Luiz C., Pereira, Lívia C., Zimmermann, Patrícia M., Brum Junior, Liberato, Rechia, Letícia M., Dias, Isabella, Hallak, Jaime E., Campos, Alline C., Guimarães, Francisco S., Queiroz, Regina H., Zuardi, Antonio W.

“…Objective: To compare plasma concentrations of cannabidiol (CBD) following oral administration of two formulations of the drug (powder and dissolved in oil),…”
Get full text

Biological bases for a possible effect of cannabidiol in Parkinson’s disease by Ferreira-Junior, Nilson C., Campos, Alline C., Guimarães, Francisco S., Del-Bel, Elaine, Zimmermann, Patrícia M. da R., Brum Junior, Liberato, Hallak, Jaime E., Crippa, José A., Zuardi, Antonio W.

“…Current pharmacotherapy of Parkinson’s disease (PD) is palliative and unable to modify the progression of neurodegeneration. Treatments that can improve…”
Get full text

Determination of Quinine and Doxycycline in Rat Plasma by LC–MS–MS: Application to a Pharmacokinetic Study by Brum Junior, Liberato, Leal, Manoela Guerra, de Toni Uchoa, Flávia, Kaiser, Moacir, Guterres, Sílvia Staniçuaski, Dalla Costa, Teresa

“…A fast, sensitive, and specific LC–MS–MS method for determination of quinine (QN) and doxycycline (DOX) in rat plasma has been developed and validated. QN,…”
Get full text

ELABORATION OF GUIDELINE FOR MONITORING IN RELATIVE BIOAVAILABILITY / PHARMACEUTICAL BIOEQUIVALENCE STUDY BY THE SPONSOR by Gozzi, Paula Thais, Bueno, Fernanda Giacomini, Zimmermann, Patrícia Moura da Rosa, Junior, Liberato Brum

“…For registration of generic and similar drugs, it is necessary to carry out pharmaceutical equivalence (PE) tests and pharmaceutical bioequivalence (PB). To…”
Get full text

Validation of an RP-LC Method and Assessment of rhG-CSF in Pharmaceutical Formulations by Liquid Chromatography and Biological Assay by Luiz Dalmora, Sergio, Maria Krug Masiero, Silvia, Renato de Oliveira, Paulo, da Silva Sangoi, Maximiliano, Brum Junior, Liberato

“…Gradient reversed-phase liquid chromatography (RP-LC) was validated for the analysis of rhG-CSF in pharmaceutical formulations. The LC method was carried out…”
Get full text

Development and Validation of a Liquid Chromatographic/ Tandem Mass Spectrometric Method for Determination of Tetracycline in Human Plasma : Application to Bioequivalence Study by BRUM JUNIOR, Liberato, PUGENS, Ana Maria, CAMILA PRITSCH, Mariely, BERTUOL MANTOVANI, Patricia, BEDIM DOS SANTOS, Mauricio, LARGER MANFIO, Josélia

“…A fast, sensitive, and specific liquid chromatographic/tandem mass spectrometric method was developed and validated for determination of tetracycline in human…”
Get full text

Validation of an LC-Tandem MS/MS Method for the Determination of Etoricoxib in Human Plasma and Pharmaceutical Formulations by Brum Junior, Liberato, Cátia Ceni, Danieli, Fronza, Marcio, Renato de Oliveira, Paulo, Luiz Dalmora, Sérgio

“…An analytical method based on liquid chromatography-tandem mass spectrometry (LC-MS/MS) was developed and validated for the determination of etoricoxib in…”
Get full text

Validation of an RP-LCG method and assessment of rhG-CSF in pharmaceutical formulations by liquid chromatography and biological assay by DALMORA, Sergio Luiz, KRUG MASIERO, Silvia Maria, RENATO DE OLIVEIRA, Paulo, DA SILVA SANGOI, Maximiliano, BRUM JUNIOR, Liberato

Get full text

DESAFIOS DO DESENVOLVIMENTO DOS DOSSIÊS DE REGISTRO DE MEDICAMENTOS FITOTERÁPICOS by Manfio, Joselia Larger, Junior, Liberato Brum

“…Os benefícios da utilização de plantas medicinais são amplamente discutidos no âmbito acadêmico através de pesquisa básica e pela população em geral, baseado…”
Get full text

Validation of the anti-factor IIa assay and potency assessment of enoxaparin in pharmaceutical formulations by Dalmora, Sérgio Luiz, Junior, Liberato Brum, Vaccari, Silvana Ferreira, Fronza, Marcio, Renato de Oliveira, Paulo, Rolim, Clarice Madalena Bueno

“…The low molecular weight heparin enoxaparin sodium is used clinically for the prevention and treatment of venous and arterial thrombosis. An anti-factor IIa…”
Get full text

Determinação do prazo de validade do medicamento carbocisteína xarope através do método de Arrhenius by Manfio, Josélia Larger, Dal'Maso, Alexandre, Pugens, Ana Maria, Brum Junior, Liberato, Steppe, Martin

Get full text