Search Results - "BRUM, ILMA SIMONI"
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Dental biofilm of symptomatic COVID‐19 patients harbours SARS‐CoV‐2
Published in Journal of clinical periodontology (01-07-2021)“…Aims SARS‐CoV‐2 RNA has been recovered from different sites in the human body, including the mouth. The present study aimed to investigate the presence of…”
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2
Detection of SARS-CoV-2 variants related mutations in wastewater using RT-qPCR and variant-specific probes in Porto Alegre, Southern Brazil
Published in Journal of water and health (01-10-2024)“…The COVID-19 pandemic has underscored the significance of monitoring genetic variations in pathogenic viruses to manage its transmission and identify emerging…”
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3
Androgen receptor isoforms expression in benign prostatic hyperplasia and primary prostate cancer
Published in PloS one (20-07-2018)“…The role of molecular changes in the androgen receptor (AR) as AR variants (AR-Vs) is not clear in the pathophysiology of benign prostatic hyperplasia (BPH)…”
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4
The impact of telomere length on prostate cancer aggressiveness, genomic instability and health disparities
Published in Scientific reports (02-04-2024)“…The telomere repetitive TTAGGG motif at the ends of chromosomes, serves to preserve genomic integrity and chromosomal stability. In turn, genomic instability…”
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5
Androgenic modulation of AR-Vs
Published in Endocrine (01-11-2018)“…Purpose The importance of androgen receptor variants (AR-Vs) is recognized in prostate cancer. AR-Vs have been the focus of many studies. Expression of AR-Vs…”
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6
Genome-wide interrogation of structural variation reveals novel African-specific prostate cancer oncogenic drivers
Published in Genome medicine (31-08-2022)“…African ancestry is a significant risk factor for advanced prostate cancer (PCa). Mortality rates in sub-Saharan Africa are 2.5-fold greater than global…”
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7
Exploring the frequency of a TP53 polyadenylation signal variant in tumor DNA from patients diagnosed with lung adenocarcinomas, sarcomas and uterine leiomyomas
Published in Genetics and molecular biology (01-01-2023)“…The TP53 3'UTR variant rs78378222 A>C has been detected in different tumor types as a somatic alteration that reduces p53 expression through modification of…”
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8
Selection of developmentally competent human oocytes aspirated during cesarean section
Published in The journal of maternal-fetal & neonatal medicine (19-03-2018)“…Purpose: To evaluate the efficiency/safety of Brilliant Cresyl Blue (BCB) staining as a selection method of developmentally competent immature human oocytes…”
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9
PSA secretion and cell proliferation are affected by NCoR1 silencing in prostate cancer cells
Published in Clinical and Biomedical Research (14-07-2020)“…The androgen receptor (AR) plays an important role in normal prostate gland development as well as in prostatic neoplasms. Transcriptional regulation by AR is…”
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10
Progesterone Upregulates Gene Expression in Normal Human Thyroid Follicular Cells
Published in International Journal of Endocrinology (01-01-2015)“…Thyroid cancer and thyroid nodules are more prevalent in women than men, so female sex hormones may have an etiological role in these conditions. There are no…”
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11
Protein expression of estrogen receptors α and β and aromatase in myometrium and uterine leiomyoma
Published in Gynecologic and obstetric investigation (01-01-2012)“…Leiomyomas are the most common tumors of the female reproductive tract and a major public health problem. The mechanism of tumorigenesis is unknown, but…”
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12
Gene and protein expression of progesterone receptor isoforms A and B, p53 and p21 in myometrium and uterine leiomyoma
Published in Archives of gynecology and obstetrics (01-07-2012)“…Purpose To assess gene and protein expression of progesterone receptor isoforms A and B, cell cycle regulators p53 and p21 in leiomyoma and myometrium. Methods…”
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13
Decreased Expression of GPER1 Gene and Protein in Goiter
Published in International Journal of Endocrinology (01-01-2015)“…Goiter is more common in women, suggesting that estrogen could be involved in its physiopathology. The presence of classical estrogen receptors (ERα and ERβ)…”
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14
Ovarian Tissue Culture to Preserve Fertility in Transgender Male Patients after Hormonal Treatment
Published in Revista Brasileira de ginecologia e obstetrícia (01-03-2022)“…To evaluate the reproductive and histological characteristics of fresh cultured ovarian tissue from transgender male patients. An in vitro pilot study in…”
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15
Are growth factor receptors modulated by metformin in human endometrial stromal cells after stimulation with androgen and insulin?
Published in Archives of gynecology and obstetrics (01-08-2014)“…Objective To assess the effect of metformin on gene and protein expression of insulin receptor (IR) and IGF-1 (IGF-1R) receptor in human endometrial stromal…”
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16
Androgen receptor CAG polymorphism and the risk of benign prostatic hyperplasia in a Brazilian population
Published in International Brazilian journal of urology (01-06-2012)“…Benign prostatic hyperplasia (BPH) is a very frequent age-related proliferative abnormality in men. Polymorphic CAG repeat in the androgen receptor (AR) can…”
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17
Gene expression and tyrosine kinase activity of insulin receptor in uterine leiomyoma and matched myometrium
Published in Archives of gynecology and obstetrics (01-11-2004)“…Our objective was to determine the insulin receptor (IR) mRNA levels and IR tyrosine kinase activity in normal myometrium and leiomyoma. Experimental study…”
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18
Progesterone receptors A and B and estrogen receptor alpha expression in normal breast tissue and fibroadenomas
Published in Endocrine (01-06-2009)Get full text
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19
Insulin stimulation of Akt/PKB phosphorylation in the placenta of preeclampsia patients
Published in São Paulo medical journal (01-12-2011)“…Preeclampsia is a multi-systemic disease and one of the most frequent severe health problems during pregnancy. Binding of insulin triggers phosphorylation and…”
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Signalization of Akt/PKB in the placenta, skeletal muscle and adipose tissue of preeclampsia patients
Published in Gynecologic and obstetric investigation (01-01-2008)“…Preeclampsia (PE) is a significant cause of fetal and maternal mortality around the world and there is evidence that insulin resistance has been implicated in…”
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